Tracking of intertissue migration reveals the origins of tumor-infiltrating monocytes

Myeloid cells such as monocytes and monocyte-derived macrophages promote tumor progression. Recent reports suggest that extramedullary hematopoiesis sustains a sizable reservoir of tumor-infiltrating monocytes in the spleen. However, the influence of the spleen on tumor development and the extent to...

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Bibliographic Details
Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 111; no. 21; p. 7771
Main Authors:	Shand, Francis H W, Ueha, Satoshi, Otsuji, Mikiya, Koid, Suang Suang, Shichino, Shigeyuki, Tsukui, Tatsuya, Kosugi-Kanaya, Mizuha, Abe, Jun, Tomura, Michio, Ziogas, James, Matsushima, Kouji
Format:	Journal Article
Language:	English
Published:	United States 27.05.2014
Subjects:	Analysis of Variance Animals Bone Marrow Cells - immunology Carcinogenesis - immunology Cell Movement - immunology Fluorescence Hematopoiesis - physiology Male Mice Mice, Inbred C57BL Monocytes - immunology Spleen - cytology Spleen - immunology tumor-associated macrophage KikGR Fucci cancer immunity monocytopoiesis
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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