2D-electrophoresis and multiplex immunoassay proteomic analysis of different body fluids and cellular components reveal known and novel markers for extended fasting

Background Proteomic technologies applied for profiling human biofluids and blood cells are considered to reveal new biomarkers of exposure or provide insights into novel mechanisms of adaptation. Methods Both a non-targeted (classical 2D-electrophoresis combined with mass spectrometry) as well as a...

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Veröffentlicht in:	BMC medical genomics Jg. 4; H. 1; S. 24
Hauptverfasser:	Bouwman, Freek G, de Roos, Baukje, Rubio-Aliaga, Isabel, Crosley, L Katie, Duthie, Susan J, Mayer, Claus, Horgan, Graham, Polley, Abigael C, Heim, Carolin, Coort, Susan LM, Evelo, Chris T, Mulholland, Francis, Johnson, Ian T, Elliott, Ruan M, Daniel, Hannelore, Mariman, Edwin CM
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 25.03.2011 BioMed Central Ltd Springer Nature B.V BMC
Schlagworte:	Apolipoproteins A - blood Biological markers Biological variation Biomarkers Biomarkers - metabolism Biomedical and Life Sciences Biomedicine Blood Blood Cells - metabolism Blood platelets Body fluids Body Fluids - metabolism Cluster Analysis Design Electrophoresis Electrophoresis, Gel, Two-Dimensional Experiments Fasting Gene Expression Guanine Nucleotide Dissociation Inhibitors - metabolism Human Genetics Humans Immunoassay Leptin - metabolism Mass Spectrometry Matrix Metalloproteinase 3 - metabolism Medical research Microarrays Nutrition Nutrition research Physiological aspects Plasma Principal Component Analysis Prognostics and diagnostics/biomarkers Proteins Proteome - metabolism Proteomics Proteomics - methods Research Article Research parks rho Guanine Nucleotide Dissociation Inhibitor beta rho-Specific Guanine Nucleotide Dissociation Inhibitors Time Factors Tumor Suppressor Proteins - metabolism United Kingdom Netherlands Germany Random Forest Analysis Multiplex Immunoassay Peripheral Blood Mononuclear Cell Random Forest MALDI Target Plate
ISSN:	1755-8794, 1755-8794
Online-Zugang:	Volltext
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