Preeclampsia; short and long-term consequences for mother and neonate
Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with...
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| Vydané v: | Early human development Ročník 102; s. 47 - 50 |
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| Hlavní autori: | , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Ireland
Elsevier Ireland Ltd
01.11.2016
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| Predmet: | |
| ISSN: | 0378-3782, 1872-6232, 1872-6232 |
| On-line prístup: | Získať plný text |
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| Abstract | Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life.
In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia. |
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| AbstractList | Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life.
In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia. Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life. In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia. Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life. In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia.Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life. In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia. Abstract Preeclampsia is a common pregnancy specific disease, that presents with hypertension and a variety of organ failures, including malfunction of kidneys, liver and lungs. At present, the only definitive treatment of preeclampsia is end the pregnancy and deliver the neonate and placenta. For women with mild preeclampsia in the preterm phase of pregnancy, expectant management is generally indicated to improve fetal maturity, often requiring maternal medical treatment. Last decades, more evidence is available that the underlying mechanism of preeclampsia, endothelial disease, is not limited to pregnancy but increases cardiovascular risk in later life. In this review, we present the most recent insight in preeclampsia with focus on impact on the fetus, short and long-term outcome of offspring's, and long-term outcome of women with a history of preeclampsia. |
| Author | Mol, Ben Willem van Weissenbruch, Mirjam de Groot, Christianne J.M. Bokslag, Anouk |
| Author_xml | – sequence: 1 givenname: Anouk surname: Bokslag fullname: Bokslag, Anouk email: a.bokslag@vumc.nl organization: Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam, The Netherlands – sequence: 2 givenname: Mirjam surname: van Weissenbruch fullname: van Weissenbruch, Mirjam email: m.vanweissenbruch@vumc.nl organization: Department of Pediatrics, Division of Neonatology, VU University Medical Center, Amsterdam, The Netherlands – sequence: 3 givenname: Ben Willem surname: Mol fullname: Mol, Ben Willem email: ben.mol@adelaide.edu.au organization: The Robinson Research Institute, School of Medicine, University of Adelaide, Adelaide, Australia – sequence: 4 givenname: Christianne J.M. surname: de Groot fullname: de Groot, Christianne J.M. email: cj.degroot@vumc.nl organization: Department of Obstetrics and Gynaecology, VU University Medical Center, Amsterdam, The Netherlands |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27659865$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Advanced Basic Science Child Development Female Fetal outcome Humans Infant, Newborn Maternal Health Neonatal and Perinatal Medicine Pre-Eclampsia - diagnosis Pre-Eclampsia - epidemiology Pre-Eclampsia - therapy Preeclampsia Pregnancy Prenatal Exposure Delayed Effects - epidemiology |
| Title | Preeclampsia; short and long-term consequences for mother and neonate |
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