Multiplying the efficiency and impact of biofortification through metabolic engineering
Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencie...
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| Vydáno v: | Nature communications Ročník 11; číslo 1; s. 5203 - 10 |
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| Hlavní autoři: | , , , , , , , , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | angličtina |
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London
Nature Publishing Group UK
15.10.2020
Nature Publishing Group Nature Portfolio |
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| ISSN: | 2041-1723, 2041-1723 |
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| Abstract | Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.
Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches. |
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| AbstractList | Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches. Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches. Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches. |
| ArticleNumber | 5203 |
| Author | Qaim, Matin Bouis, Howarth Van Montagu, Marc Van Der Straeten, Dominique Pfeiffer, Wolfgang Gruissem, Wilhelm De Steur, Hans MacKenzie, Donald Zhang, Chunyi Slamet-Loedin, Inez Strobbe, Simon Vanderschuren, Hervé Tohme, Joe Trijatmiko, Kurniawan Rudi Bhullar, Navreet K. |
| Author_xml | – sequence: 1 givenname: Dominique orcidid: 0000-0002-7755-1420 surname: Van Der Straeten fullname: Van Der Straeten, Dominique email: Dominique.VanDerStraeten@UGent.be organization: Laboratory of Functional Plant Biology, Department of Biology, Ghent University – sequence: 2 givenname: Navreet K. orcidid: 0000-0003-1657-0422 surname: Bhullar fullname: Bhullar, Navreet K. organization: Department of Biology, Institute of Molecular Plant Biology, ETH Zurich – sequence: 3 givenname: Hans orcidid: 0000-0003-1340-0882 surname: De Steur fullname: De Steur, Hans organization: Department of Agricultural Economics, Ghent University – sequence: 4 givenname: Wilhelm surname: Gruissem fullname: Gruissem, Wilhelm organization: Department of Biology, Institute of Molecular Plant Biology, ETH Zurich, Advanced Plant Biotechnology Center, National Chung Hsing University – sequence: 5 givenname: Donald orcidid: 0000-0002-9979-8299 surname: MacKenzie fullname: MacKenzie, Donald organization: Donald Danforth Plant Science Center – sequence: 6 givenname: Wolfgang surname: Pfeiffer fullname: Pfeiffer, Wolfgang organization: HarvestPlus c/o IFPRI – sequence: 7 givenname: Matin orcidid: 0000-0003-4143-0763 surname: Qaim fullname: Qaim, Matin organization: Department of Agricultural Economics and Rural Development, University of Goettingen – sequence: 8 givenname: Inez surname: Slamet-Loedin fullname: Slamet-Loedin, Inez organization: International Rice Research Institute – sequence: 9 givenname: Simon orcidid: 0000-0003-0583-9406 surname: Strobbe fullname: Strobbe, Simon organization: Laboratory of Functional Plant Biology, Department of Biology, Ghent University – sequence: 10 givenname: Joe surname: Tohme fullname: Tohme, Joe organization: International Center for Tropical Agriculture, CIAT – sequence: 11 givenname: Kurniawan Rudi orcidid: 0000-0002-6440-9150 surname: Trijatmiko fullname: Trijatmiko, Kurniawan Rudi organization: International Rice Research Institute – sequence: 12 givenname: Hervé orcidid: 0000-0003-2102-9737 surname: Vanderschuren fullname: Vanderschuren, Hervé organization: Tropical Crop Improvement Lab, Department of Biosystems, KU Leuven, Plant Genetics, TERRA Teaching and Research Center, Gembloux Agro-Biotech, University of Liège – sequence: 13 givenname: Marc orcidid: 0000-0003-4711-5131 surname: Van Montagu fullname: Van Montagu, Marc organization: International Plant Biotechnology Outreach – sequence: 14 givenname: Chunyi orcidid: 0000-0001-5685-6412 surname: Zhang fullname: Zhang, Chunyi organization: Biotechnology Research Institute, Chinese Academy of Agricultural Sciences – sequence: 15 givenname: Howarth orcidid: 0000-0001-5432-9192 surname: Bouis fullname: Bouis, Howarth email: H.Bouis@CGIAR.org organization: International Food Policy Research Institute |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33060603$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1111/tpj.14379 10.1080/21645698.2017.1301331 10.1159/000371618 10.1016/j.nbt.2011.11.012 10.1016/j.molp.2017.12.008 10.1111/pbi.12373 10.1007/s00425-015-2314-4 10.2174/1874331501812010036 10.1111/j.1467-7652.2009.00430.x 10.1016/j.foodchem.2018.11.121 10.1093/mp/ssr099 10.1016/j.jik.2017.12.006 10.1016/j.copbio.2016.12.003 10.1105/tpc.111.093120 10.1007/s11103-019-00913-y 10.1021/acs.jafc.9b01524 10.1021/acs.jafc.5b04279 10.3945/jn.116.239202 10.1016/S0140-6736(13)60937-X 10.1002/aepp.13044 10.1016/j.gfs.2017.01.004 10.1016/S0140-6736(16)31678-6 10.1038/nbt1082 10.1038/s41477-019-0430-z 10.1146/annurev-nutr-071816-064627 10.1007/s11103-018-00819-1 10.1111/j.1469-8137.2008.02738.x 10.1038/nbt1351 10.1007/s12284-010-9042-y 10.1016/j.copbio.2017.01.012 10.1007/s12284-011-9061-3 10.1073/pnas.1605689113 10.3945/an.114.006627 10.1126/science.287.5451.303 10.1038/nbt.3358 10.1016/j.gfs.2017.01.009 10.1111/pbi.12862 10.1021/jf501233f 10.3389/fnut.2018.00012 10.1038/nrendo.2016.37 10.1111/pbi.12943 10.1104/pp.113.217661 10.1038/s41598-016-0028-x 10.1126/science.aav6316 10.1038/nbt.2405 10.1016/j.pcad.2020.07.002 10.1093/jxb/ery453 10.1038/srep19792 10.1080/16549716.2019.1588513 10.1371/journal.pone.0175554 10.1186/s12937-018-0391-5 10.1371/journal.pone.0143497 10.1093/nutrit/nuaa063 10.1002/14651858.CD008524.pub3 10.1038/s41467-019-13993-7 |
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| References | Garg (CR6) 2018; 5 Li (CR46) 2015; 33 Bollinedi (CR38) 2019; 278 Low, Mwanga, Andrade, Carey, Ball (CR10) 2017; 14 De Lepeleire (CR47) 2018; 11 CR39 Storozhenko (CR45) 2007; 25 Strobbe, Van Der Straeten (CR44) 2017; 44 Lee (CR70) 2019; 99 CR32 Dong (CR62) 2020; 11 Blancquaert (CR50) 2015; 33 Fitzpatrick (CR2) 2012; 24 CR4 CR3 CR5 Bashir, Ishimaru, Nishizawa (CR29) 2010; 3 CR8 CR9 Gernand, Schulze, Stewart, West, Christian (CR61) 2016; 12 CR48 Paine (CR36) 2005; 23 Wu, Gruissem, Bhullar (CR33) 2019; 17 CR43 Flores, Vellozzi, Valencia, Sniezek (CR20) 2014; 26 CR42 Vos (CR17) 2016; 388 CR41 CR40 Li (CR52) 2012; 5 Mugode (CR51) 2014; 62 Che (CR56) 2016; 113 Black (CR18) 2013; 382 Ye (CR35) 2000; 287 Bouis, Saltzman (CR7) 2017; 12 Zou (CR34) 2019; 32 Bai (CR53) 2016; 14 CR16 Ishimaru, Bashir, Nishizawa (CR30) 2011; 4 CR15 CR59 Vanderschuren (CR72) 2012; 30 CR14 CR13 Swamy (CR37) 2019; 67 CR12 Alderman, Fernald (CR19) 2017; 37 Lee (CR73) 2018; 12 Beyene (CR63) 2018; 16 Joshi, Nayak (CR57) 2010; 5 Matveeva, Otten (CR74) 2019; 101 White, Broadley (CR1) 2009; 182 Singh, Gruissem, Bhullar (CR60) 2017; 7 Napier, Haslam, Tsalavouta, Sayanova (CR66) 2019; 5 De Steur, Demont, Gellynck, Stein (CR64) 2017; 44 Andersson, Saltzman, Virk, Pfeiffer (CR27) 2017; 17 De Moura (CR24) 2014; 5 De Steur (CR65) 2012; 29 Palmer (CR25) 2016; 146 CR28 Zaidi (CR68) 2019; 363 Sarrion-Perdigones (CR69) 2013; 162 Mangel (CR49) 2019; 99 de Cerqueira, Schafer, Fast, Herman (CR58) 2017; 8 CR26 CR23 CR22 CR21 Gayen, Ali, Sarkar, Datta, Datta (CR54) 2015; 242 Wirth (CR31) 2009; 7 Roberts (CR71) 2018; 3 Qaim (CR67) 2020; 42 Bailey, West, Black (CR11) 2015; 66 Zeng (CR55) 2015; 63 C Bai (19020_CR53) 2016; 14 L Mugode (19020_CR51) 2014; 62 RE Black (19020_CR18) 2013; 382 AL Flores (19020_CR20) 2014; 26 KT Li (19020_CR46) 2015; 33 K Lee (19020_CR70) 2019; 99 C Zou (19020_CR34) 2019; 32 SP Singh (19020_CR60) 2017; 7 TB Fitzpatrick (19020_CR2) 2012; 24 M Garg (19020_CR6) 2018; 5 19020_CR15 19020_CR59 19020_CR16 P Che (19020_CR56) 2016; 113 JW Low (19020_CR10) 2017; 14 19020_CR13 K Bashir (19020_CR29) 2010; 3 19020_CR14 19020_CR12 DTR de Cerqueira (19020_CR58) 2017; 8 H Vanderschuren (19020_CR72) 2012; 30 19020_CR3 J Wirth (19020_CR31) 2009; 7 D Gayen (19020_CR54) 2015; 242 19020_CR4 19020_CR5 HE Bouis (19020_CR7) 2017; 12 MS Andersson (19020_CR27) 2017; 17 19020_CR48 JA Paine (19020_CR36) 2005; 23 AC Palmer (19020_CR25) 2016; 146 19020_CR42 19020_CR43 19020_CR8 19020_CR40 19020_CR9 19020_CR41 H Alderman (19020_CR19) 2017; 37 FF De Moura (19020_CR24) 2014; 5 RL Bailey (19020_CR11) 2015; 66 H De Steur (19020_CR64) 2017; 44 A Sarrion-Perdigones (19020_CR69) 2013; 162 OX Dong (19020_CR62) 2020; 11 SSEA Zaidi (19020_CR68) 2019; 363 19020_CR39 H Bollinedi (19020_CR38) 2019; 278 TY Wu (19020_CR33) 2019; 17 AD Gernand (19020_CR61) 2016; 12 BPM Swamy (19020_CR37) 2019; 67 19020_CR32 RJ Roberts (19020_CR71) 2018; 3 PJ White (19020_CR1) 2009; 182 T Vos (19020_CR17) 2016; 388 JA Napier (19020_CR66) 2019; 5 S Strobbe (19020_CR44) 2017; 44 N Mangel (19020_CR49) 2019; 99 TV Matveeva (19020_CR74) 2019; 101 XD Ye (19020_CR35) 2000; 287 D Blancquaert (19020_CR50) 2015; 33 H De Steur (19020_CR65) 2012; 29 RK Joshi (19020_CR57) 2010; 5 S Storozhenko (19020_CR45) 2007; 25 19020_CR28 Y Ishimaru (19020_CR30) 2011; 4 L Li (19020_CR52) 2012; 5 19020_CR26 J Zeng (19020_CR55) 2015; 63 J De Lepeleire (19020_CR47) 2018; 11 19020_CR22 H Lee (19020_CR73) 2018; 12 19020_CR23 19020_CR21 G Beyene (19020_CR63) 2018; 16 M Qaim (19020_CR67) 2020; 42 |
| References_xml | – ident: CR22 – volume: 33 start-page: 1029 year: 2015 end-page: 1032 ident: CR46 article-title: Increased bioavailable vitamin B-6 in field-grown transgenic cassava for dietary sufficiency publication-title: Nat. Biotechnol. – volume: 99 start-page: 1047 year: 2019 end-page: 1065 ident: CR49 article-title: Enhancement of vitamin B-6 levels in rice expressing vitamin B-6 biosynthesis de novo genes publication-title: Plant J. doi: 10.1111/tpj.14379 – volume: 8 start-page: 149 year: 2017 end-page: 155 ident: CR58 article-title: Agronomic performance of insect-protected and herbicide-tolerant MON 89034 x TC1507 x NK603 x DAS-40278-9 corn is equivalent to that of conventional corn publication-title: GM Crops Food doi: 10.1080/21645698.2017.1301331 – volume: 66 start-page: 22 year: 2015 end-page: 33 ident: CR11 article-title: The epidemiology of global micronutrient deficiencies publication-title: Ann. Nutr. Metab. doi: 10.1159/000371618 – volume: 29 start-page: 432 year: 2012 end-page: 442 ident: CR65 article-title: Potential impact and cost-effectiveness of multi-biofortified rice in China publication-title: New Biotechnol. doi: 10.1016/j.nbt.2011.11.012 – volume: 11 start-page: 175 year: 2018 end-page: 188 ident: CR47 article-title: Folate biofortification of potato by tuber-specific expression of four folate biosynthesis genes publication-title: Mol. Plant doi: 10.1016/j.molp.2017.12.008 – volume: 14 start-page: 195 year: 2016 end-page: 205 ident: CR53 article-title: Bottlenecks in carotenoid biosynthesis and accumulation in rice endosperm are influenced by the precursor-product balance publication-title: Plant Biotechnol. J. doi: 10.1111/pbi.12373 – volume: 242 start-page: 353 year: 2015 end-page: 363 ident: CR54 article-title: Down-regulation of lipoxygenase gene reduces degradation of carotenoids of golden rice during storage publication-title: Planta doi: 10.1007/s00425-015-2314-4 – volume: 12 start-page: 36 year: 2018 end-page: 45 ident: CR73 article-title: Capacity building for agricultural biotechnology in developing countries publication-title: Open Agric. J. doi: 10.2174/1874331501812010036 – ident: CR4 – volume: 7 start-page: 718 year: 2009 end-page: 718 ident: CR31 article-title: Rice endosperm iron biofortification by targeted and synergistic action of nicotianamine synthase and ferritin publication-title: Plant Biotechnol. J. doi: 10.1111/j.1467-7652.2009.00430.x – ident: CR39 – ident: CR16 – ident: CR12 – volume: 17 start-page: 11905 year: 2017 end-page: 11935 ident: CR27 article-title: Progress update: crop development of biofortified staple food crops under HarvestPlus publication-title: Afr. J. Food Agric. Nutr. Dev. – ident: CR8 – volume: 278 start-page: 773 year: 2019 end-page: 779 ident: CR38 article-title: Kinetics of beta-carotene degradation under different storage conditions in transgenic Golden Rice (R) lines publication-title: Food Chem. doi: 10.1016/j.foodchem.2018.11.121 – ident: CR42 – volume: 5 start-page: 339 year: 2012 end-page: 352 ident: CR52 article-title: The gene enhances carotenoid accumulation and stability during post-harvest storage of potato tubers publication-title: Mol. Plant doi: 10.1093/mp/ssr099 – volume: 3 start-page: 61 year: 2018 end-page: 65 ident: CR71 article-title: The Nobel laureates’ campaign supporting GMOs publication-title: J. Innov. Knowl. doi: 10.1016/j.jik.2017.12.006 – volume: 44 start-page: 202 year: 2017 end-page: 211 ident: CR44 article-title: Folate biofortification in food crops publication-title: Curr. Opin. Biotechnol. doi: 10.1016/j.copbio.2016.12.003 – volume: 11 start-page: 1 year: 2020 end-page: 10 ident: CR62 article-title: Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9 publication-title: Nat. Commun. – ident: CR21 – volume: 24 start-page: 395 year: 2012 end-page: 414 ident: CR2 article-title: Vitamin deficiencies in humans: can plant science help? publication-title: Plant Cell doi: 10.1105/tpc.111.093120 – volume: 101 start-page: 415 year: 2019 end-page: 437 ident: CR74 article-title: Widespread occurrence of natural genetic transformation of plants by publication-title: Plant Mol. Biol. doi: 10.1007/s11103-019-00913-y – volume: 67 start-page: 7986 year: 2019 end-page: 7994 ident: CR37 article-title: Compositional analysis of genetically engineered GR2E “Golden Rice” in comparison to that of conventional rice publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.9b01524 – volume: 63 start-page: 9083 year: 2015 end-page: 9092 ident: CR55 article-title: Metabolic engineering of wheat provitamin A by simultaneously overexpressing CrtB and silencing carotenoid hydroxylase (TaHYD) publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.5b04279 – volume: 146 start-page: 2551 year: 2016 end-page: 2558 ident: CR25 article-title: Provitamin A carotenoid-biofortified maize consumption increases pupillary responsiveness among Zambian children in a randomized controlled trial publication-title: J. Nutr. doi: 10.3945/jn.116.239202 – ident: CR15 – volume: 382 start-page: 427 year: 2013 end-page: 451 ident: CR18 article-title: Maternal and child undernutrition and overweight in low-income and middle-income countries publication-title: Lancet doi: 10.1016/S0140-6736(13)60937-X – volume: 42 start-page: 129 year: 2020 end-page: 150 ident: CR67 article-title: Role of new plant breeding technologies for food security and sustainable agricultural development publication-title: Appl. Econ. Perspect. Policy doi: 10.1002/aepp.13044 – volume: 26 start-page: 3 year: 2014 end-page: 5 ident: CR20 article-title: Global burden of neural tube defects, risk factors, and prevention publication-title: Indian J. Community Health – ident: CR9 – ident: CR32 – ident: CR5 – volume: 14 start-page: 23 year: 2017 end-page: 30 ident: CR10 article-title: Tackling vitamin A deficiency with biofortified sweetpotato in sub-Saharan Africa publication-title: Glob. Food Sec. doi: 10.1016/j.gfs.2017.01.004 – volume: 388 start-page: 1545 year: 2016 end-page: 1602 ident: CR17 article-title: Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the global burden of disease study 2015 publication-title: Lancet doi: 10.1016/S0140-6736(16)31678-6 – volume: 23 start-page: 482 year: 2005 end-page: 487 ident: CR36 article-title: Improving the nutritional value of Golden Rice through increased pro-vitamin A content publication-title: Nat. Biotechnol. doi: 10.1038/nbt1082 – volume: 5 start-page: 563 year: 2019 end-page: 567 ident: CR66 article-title: The challenges of delivering genetically modified crops with nutritional enhancement traits publication-title: Nat. Plants doi: 10.1038/s41477-019-0430-z – ident: CR26 – volume: 37 start-page: 447 year: 2017 end-page: 476 ident: CR19 article-title: The nexus between nutrition and early childhood development publication-title: Annu. Rev. Nutr. doi: 10.1146/annurev-nutr-071816-064627 – volume: 99 start-page: 317 year: 2019 end-page: 328 ident: CR70 article-title: CRISPR/Cas9-mediated targeted T-DNA integration in rice publication-title: Plant Mol. Biol. doi: 10.1007/s11103-018-00819-1 – volume: 32 start-page: 854 year: 2019 end-page: 859 ident: CR34 article-title: Effects of foliar spraying of selenium fertilizer on yield, selenium content and heavy metals content in waxy maize publication-title: Southwest China J. Agric. Sci. – ident: CR43 – volume: 182 start-page: 49 year: 2009 end-page: 84 ident: CR1 article-title: Biofortification of crops with seven mineral elements often lacking in human diets - iron, zinc, copper, calcium, magnesium, selenium and iodine publication-title: New Phytol. doi: 10.1111/j.1469-8137.2008.02738.x – ident: CR14 – volume: 25 start-page: 1277 year: 2007 end-page: 1279 ident: CR45 article-title: Folate fortification of rice by metabolic engineering publication-title: Nat. Biotechnol. doi: 10.1038/nbt1351 – volume: 3 start-page: 122 year: 2010 end-page: 130 ident: CR29 article-title: Iron uptake and loading into rice grains publication-title: Rice doi: 10.1007/s12284-010-9042-y – volume: 44 start-page: 161 year: 2017 end-page: 168 ident: CR64 article-title: The social and economic impact of biofortification through genetic modification publication-title: Curr. Opin. Biotechnol. doi: 10.1016/j.copbio.2017.01.012 – volume: 4 start-page: 21 year: 2011 end-page: 27 ident: CR30 article-title: Zn uptake and translocation in rice plants publication-title: Rice doi: 10.1007/s12284-011-9061-3 – ident: CR40 – volume: 113 start-page: 11040 year: 2016 end-page: 11045 ident: CR56 article-title: Elevated vitamin E content improves all-trans beta-carotene accumulation and stability in biofortified sorghum publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1605689113 – ident: CR23 – volume: 5 start-page: 568 year: 2014 end-page: 570 ident: CR24 article-title: Are biofortified staple food crops improving vitamin A and iron status in women and children? New evidence from efficacy trials publication-title: Adv. Nutr. doi: 10.3945/an.114.006627 – volume: 287 start-page: 303 year: 2000 end-page: 305 ident: CR35 article-title: Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm publication-title: Science doi: 10.1126/science.287.5451.303 – ident: CR48 – volume: 33 start-page: 1076 year: 2015 end-page: 1078 ident: CR50 article-title: Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering publication-title: Nat. Biotechnol. doi: 10.1038/nbt.3358 – volume: 12 start-page: 49 year: 2017 end-page: 58 ident: CR7 article-title: Improving nutrition through biofortification: a review of evidence from HarvestPlus, 2003 through 2016 publication-title: Glob. Food Sec. doi: 10.1016/j.gfs.2017.01.009 – ident: CR3 – volume: 16 start-page: 1186 year: 2018 end-page: 1200 ident: CR63 article-title: Provitamin A biofortification of cassava enhances shelf life but reduces dry matter content of storage roots due to altered carbon partitioning into starch publication-title: Plant Biotechnol. J. doi: 10.1111/pbi.12862 – volume: 62 start-page: 6317 year: 2014 end-page: 6325 ident: CR51 article-title: Carotenoid retention of biofortified provitamin A maize ( .) after Zambian traditional methods of milling, cooking and storage publication-title: J. Agric. Food Chem. doi: 10.1021/jf501233f – volume: 5 start-page: 12 year: 2018 ident: CR6 article-title: Biofortified crops generated by breeding, agronomy and transgenic approaches are improving lives of millions of people around the world publication-title: Front. Nutr. doi: 10.3389/fnut.2018.00012 – ident: CR13 – volume: 5 start-page: 51 year: 2010 end-page: 60 ident: CR57 article-title: Gene pyramiding-A broad spectrum technique for developing durable stress resistance in crops publication-title: Biotechnol. Mol. Biol. Rev. – volume: 12 start-page: 274 year: 2016 end-page: 289 ident: CR61 article-title: Micronutrient deficiencies in pregnancy worldwide: health effects and prevention publication-title: Nat. Rev. Endocrinol. doi: 10.1038/nrendo.2016.37 – volume: 17 start-page: 9 year: 2019 end-page: 20 ident: CR33 article-title: Targeting intracellular transport combined with efficient uptake and storage significantly increases grain iron and zinc levels in rice publication-title: Plant Biotechnol. J. doi: 10.1111/pbi.12943 – volume: 162 start-page: 1618 year: 2013 end-page: 1631 ident: CR69 article-title: GoldenBraid 2.0: a comprehensive DNA assembly framework for plant synthetic biology publication-title: Plant Physiol. doi: 10.1104/pp.113.217661 – ident: CR59 – ident: CR28 – ident: CR41 – volume: 7 start-page: 1 year: 2017 end-page: 11 ident: CR60 article-title: Single genetic locus improvement of iron, zinc and beta-carotene content in rice grains publication-title: Sci. Rep. doi: 10.1038/s41598-016-0028-x – volume: 363 start-page: 1390 year: 2019 end-page: 1391 ident: CR68 article-title: New plant breeding technologies for food security publication-title: Science doi: 10.1126/science.aav6316 – volume: 30 start-page: 1170 year: 2012 end-page: 1172 ident: CR72 article-title: Strengthening African R&D through effective transfer of tropical crop biotech to African institutions publication-title: Nat. Biotechnol. doi: 10.1038/nbt.2405 – volume: 67 start-page: 7986 year: 2019 ident: 19020_CR37 publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.9b01524 – ident: 19020_CR22 – volume: 5 start-page: 568 year: 2014 ident: 19020_CR24 publication-title: Adv. Nutr. doi: 10.3945/an.114.006627 – volume: 5 start-page: 51 year: 2010 ident: 19020_CR57 publication-title: Biotechnol. Mol. Biol. Rev. – volume: 33 start-page: 1029 year: 2015 ident: 19020_CR46 publication-title: Nat. Biotechnol. – volume: 12 start-page: 49 year: 2017 ident: 19020_CR7 publication-title: Glob. Food Sec. doi: 10.1016/j.gfs.2017.01.009 – ident: 19020_CR41 – ident: 19020_CR39 – ident: 19020_CR9 – ident: 19020_CR15 doi: 10.1016/j.pcad.2020.07.002 – volume: 33 start-page: 1076 year: 2015 ident: 19020_CR50 publication-title: Nat. Biotechnol. doi: 10.1038/nbt.3358 – volume: 7 start-page: 718 year: 2009 ident: 19020_CR31 publication-title: Plant Biotechnol. J. doi: 10.1111/j.1467-7652.2009.00430.x – volume: 17 start-page: 9 year: 2019 ident: 19020_CR33 publication-title: Plant Biotechnol. J. doi: 10.1111/pbi.12943 – ident: 19020_CR59 – volume: 287 start-page: 303 year: 2000 ident: 19020_CR35 publication-title: Science doi: 10.1126/science.287.5451.303 – volume: 37 start-page: 447 year: 2017 ident: 19020_CR19 publication-title: Annu. Rev. Nutr. doi: 10.1146/annurev-nutr-071816-064627 – volume: 3 start-page: 122 year: 2010 ident: 19020_CR29 publication-title: Rice doi: 10.1007/s12284-010-9042-y – volume: 278 start-page: 773 year: 2019 ident: 19020_CR38 publication-title: Food Chem. doi: 10.1016/j.foodchem.2018.11.121 – ident: 19020_CR48 doi: 10.1093/jxb/ery453 – ident: 19020_CR32 doi: 10.1038/srep19792 – volume: 182 start-page: 49 year: 2009 ident: 19020_CR1 publication-title: New Phytol. doi: 10.1111/j.1469-8137.2008.02738.x – ident: 19020_CR23 – volume: 25 start-page: 1277 year: 2007 ident: 19020_CR45 publication-title: Nat. Biotechnol. doi: 10.1038/nbt1351 – volume: 162 start-page: 1618 year: 2013 ident: 19020_CR69 publication-title: Plant Physiol. doi: 10.1104/pp.113.217661 – volume: 382 start-page: 427 year: 2013 ident: 19020_CR18 publication-title: Lancet doi: 10.1016/S0140-6736(13)60937-X – volume: 62 start-page: 6317 year: 2014 ident: 19020_CR51 publication-title: J. Agric. Food Chem. doi: 10.1021/jf501233f – volume: 99 start-page: 317 year: 2019 ident: 19020_CR70 publication-title: Plant Mol. Biol. doi: 10.1007/s11103-018-00819-1 – volume: 5 start-page: 12 year: 2018 ident: 19020_CR6 publication-title: Front. Nutr. doi: 10.3389/fnut.2018.00012 – volume: 17 start-page: 11905 year: 2017 ident: 19020_CR27 publication-title: Afr. J. Food Agric. Nutr. Dev. – volume: 5 start-page: 339 year: 2012 ident: 19020_CR52 publication-title: Mol. Plant doi: 10.1093/mp/ssr099 – volume: 101 start-page: 415 year: 2019 ident: 19020_CR74 publication-title: Plant Mol. Biol. doi: 10.1007/s11103-019-00913-y – volume: 12 start-page: 274 year: 2016 ident: 19020_CR61 publication-title: Nat. Rev. Endocrinol. doi: 10.1038/nrendo.2016.37 – volume: 44 start-page: 202 year: 2017 ident: 19020_CR44 publication-title: Curr. Opin. Biotechnol. doi: 10.1016/j.copbio.2016.12.003 – volume: 3 start-page: 61 year: 2018 ident: 19020_CR71 publication-title: J. Innov. Knowl. doi: 10.1016/j.jik.2017.12.006 – ident: 19020_CR12 – volume: 24 start-page: 395 year: 2012 ident: 19020_CR2 publication-title: Plant Cell doi: 10.1105/tpc.111.093120 – ident: 19020_CR13 doi: 10.1080/16549716.2019.1588513 – volume: 7 start-page: 1 year: 2017 ident: 19020_CR60 publication-title: Sci. Rep. doi: 10.1038/s41598-016-0028-x – volume: 66 start-page: 22 year: 2015 ident: 19020_CR11 publication-title: Ann. Nutr. Metab. doi: 10.1159/000371618 – volume: 12 start-page: 36 year: 2018 ident: 19020_CR73 publication-title: Open Agric. J. doi: 10.2174/1874331501812010036 – ident: 19020_CR3 – ident: 19020_CR5 doi: 10.1371/journal.pone.0175554 – ident: 19020_CR43 – volume: 242 start-page: 353 year: 2015 ident: 19020_CR54 publication-title: Planta doi: 10.1007/s00425-015-2314-4 – volume: 29 start-page: 432 year: 2012 ident: 19020_CR65 publication-title: New Biotechnol. doi: 10.1016/j.nbt.2011.11.012 – ident: 19020_CR26 doi: 10.1186/s12937-018-0391-5 – volume: 44 start-page: 161 year: 2017 ident: 19020_CR64 publication-title: Curr. Opin. Biotechnol. doi: 10.1016/j.copbio.2017.01.012 – volume: 11 start-page: 175 year: 2018 ident: 19020_CR47 publication-title: Mol. Plant doi: 10.1016/j.molp.2017.12.008 – volume: 113 start-page: 11040 year: 2016 ident: 19020_CR56 publication-title: Proc. Natl Acad. Sci. USA doi: 10.1073/pnas.1605689113 – volume: 30 start-page: 1170 year: 2012 ident: 19020_CR72 publication-title: Nat. Biotechnol. doi: 10.1038/nbt.2405 – ident: 19020_CR4 doi: 10.1371/journal.pone.0143497 – volume: 14 start-page: 23 year: 2017 ident: 19020_CR10 publication-title: Glob. Food Sec. doi: 10.1016/j.gfs.2017.01.004 – volume: 32 start-page: 854 year: 2019 ident: 19020_CR34 publication-title: Southwest China J. Agric. Sci. – ident: 19020_CR40 – volume: 5 start-page: 563 year: 2019 ident: 19020_CR66 publication-title: Nat. Plants doi: 10.1038/s41477-019-0430-z – ident: 19020_CR14 doi: 10.1093/nutrit/nuaa063 – volume: 16 start-page: 1186 year: 2018 ident: 19020_CR63 publication-title: Plant Biotechnol. J. doi: 10.1111/pbi.12862 – volume: 363 start-page: 1390 year: 2019 ident: 19020_CR68 publication-title: Science doi: 10.1126/science.aav6316 – volume: 146 start-page: 2551 year: 2016 ident: 19020_CR25 publication-title: J. Nutr. doi: 10.3945/jn.116.239202 – ident: 19020_CR21 – volume: 23 start-page: 482 year: 2005 ident: 19020_CR36 publication-title: Nat. Biotechnol. doi: 10.1038/nbt1082 – volume: 63 start-page: 9083 year: 2015 ident: 19020_CR55 publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.5b04279 – ident: 19020_CR42 – ident: 19020_CR8 – volume: 8 start-page: 149 year: 2017 ident: 19020_CR58 publication-title: GM Crops Food doi: 10.1080/21645698.2017.1301331 – ident: 19020_CR16 doi: 10.1002/14651858.CD008524.pub3 – volume: 4 start-page: 21 year: 2011 ident: 19020_CR30 publication-title: Rice doi: 10.1007/s12284-011-9061-3 – volume: 11 start-page: 1 year: 2020 ident: 19020_CR62 publication-title: Nat. Commun. doi: 10.1038/s41467-019-13993-7 – volume: 388 start-page: 1545 year: 2016 ident: 19020_CR17 publication-title: Lancet doi: 10.1016/S0140-6736(16)31678-6 – ident: 19020_CR28 – volume: 14 start-page: 195 year: 2016 ident: 19020_CR53 publication-title: Plant Biotechnol. J. doi: 10.1111/pbi.12373 – volume: 99 start-page: 1047 year: 2019 ident: 19020_CR49 publication-title: Plant J. doi: 10.1111/tpj.14379 – volume: 42 start-page: 129 year: 2020 ident: 19020_CR67 publication-title: Appl. Econ. Perspect. Policy doi: 10.1002/aepp.13044 – volume: 26 start-page: 3 year: 2014 ident: 19020_CR20 publication-title: Indian J. Community Health |
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| Snippet | Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited... Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking... |
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| SubjectTerms | 42/41 42/44 631/449/447/2311 631/61/318 631/61/447/8 706/1143 Biofortification - methods Biotechnologie Biotechnology Breeding Crops, Agricultural - genetics Developing Countries Food Supply Food, Fortified Global Health Humanities and Social Sciences Humans Life sciences Malnutrition - prevention & control Metabolic Engineering - methods Micronutrients Minerals multidisciplinary Oryza Perspective Plants - genetics Plants, Genetically Modified Policy Making Provitamins Science Science (multidisciplinary) Sciences du vivant Sustainable Development - economics Sustainable Development - trends Sustainable Development/economics/trends United Nations Vitamins |
| Title | Multiplying the efficiency and impact of biofortification through metabolic engineering |
| URI | https://link.springer.com/article/10.1038/s41467-020-19020-4 https://www.ncbi.nlm.nih.gov/pubmed/33060603 https://www.proquest.com/docview/2451847354 https://orbi.uliege.be/handle/2268/253682 https://pubmed.ncbi.nlm.nih.gov/PMC7567076 https://doaj.org/article/896c3ea692774bf1b95ee465d3cd0928 |
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