Multiplying the efficiency and impact of biofortification through metabolic engineering

Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencie...

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Vydáno v:Nature communications Ročník 11; číslo 1; s. 5203 - 10
Hlavní autoři: Van Der Straeten, Dominique, Bhullar, Navreet K., De Steur, Hans, Gruissem, Wilhelm, MacKenzie, Donald, Pfeiffer, Wolfgang, Qaim, Matin, Slamet-Loedin, Inez, Strobbe, Simon, Tohme, Joe, Trijatmiko, Kurniawan Rudi, Vanderschuren, Hervé, Van Montagu, Marc, Zhang, Chunyi, Bouis, Howarth
Médium: Journal Article
Jazyk:angličtina
Vydáno: London Nature Publishing Group UK 15.10.2020
Nature Publishing Group
Nature Portfolio
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ISSN:2041-1723, 2041-1723
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Abstract Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches.
AbstractList Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches.
Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.
Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal. Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches.
Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.
Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking multiple micronutrient traits into high-yielding varieties through the combination of conventional breeding and genetic engineering approaches.
ArticleNumber 5203
Author Qaim, Matin
Bouis, Howarth
Van Montagu, Marc
Van Der Straeten, Dominique
Pfeiffer, Wolfgang
Gruissem, Wilhelm
De Steur, Hans
MacKenzie, Donald
Zhang, Chunyi
Slamet-Loedin, Inez
Strobbe, Simon
Vanderschuren, Hervé
Tohme, Joe
Trijatmiko, Kurniawan Rudi
Bhullar, Navreet K.
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  orcidid: 0000-0003-1340-0882
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  organization: Department of Agricultural Economics and Rural Development, University of Goettingen
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  organization: International Rice Research Institute
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  surname: Trijatmiko
  fullname: Trijatmiko, Kurniawan Rudi
  organization: International Rice Research Institute
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  orcidid: 0000-0003-2102-9737
  surname: Vanderschuren
  fullname: Vanderschuren, Hervé
  organization: Tropical Crop Improvement Lab, Department of Biosystems, KU Leuven, Plant Genetics, TERRA Teaching and Research Center, Gembloux Agro-Biotech, University of Liège
– sequence: 13
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  orcidid: 0000-0003-4711-5131
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  givenname: Chunyi
  orcidid: 0000-0001-5685-6412
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  organization: International Food Policy Research Institute
BackLink https://www.ncbi.nlm.nih.gov/pubmed/33060603$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1111/tpj.14379
10.1080/21645698.2017.1301331
10.1159/000371618
10.1016/j.nbt.2011.11.012
10.1016/j.molp.2017.12.008
10.1111/pbi.12373
10.1007/s00425-015-2314-4
10.2174/1874331501812010036
10.1111/j.1467-7652.2009.00430.x
10.1016/j.foodchem.2018.11.121
10.1093/mp/ssr099
10.1016/j.jik.2017.12.006
10.1016/j.copbio.2016.12.003
10.1105/tpc.111.093120
10.1007/s11103-019-00913-y
10.1021/acs.jafc.9b01524
10.1021/acs.jafc.5b04279
10.3945/jn.116.239202
10.1016/S0140-6736(13)60937-X
10.1002/aepp.13044
10.1016/j.gfs.2017.01.004
10.1016/S0140-6736(16)31678-6
10.1038/nbt1082
10.1038/s41477-019-0430-z
10.1146/annurev-nutr-071816-064627
10.1007/s11103-018-00819-1
10.1111/j.1469-8137.2008.02738.x
10.1038/nbt1351
10.1007/s12284-010-9042-y
10.1016/j.copbio.2017.01.012
10.1007/s12284-011-9061-3
10.1073/pnas.1605689113
10.3945/an.114.006627
10.1126/science.287.5451.303
10.1038/nbt.3358
10.1016/j.gfs.2017.01.009
10.1111/pbi.12862
10.1021/jf501233f
10.3389/fnut.2018.00012
10.1038/nrendo.2016.37
10.1111/pbi.12943
10.1104/pp.113.217661
10.1038/s41598-016-0028-x
10.1126/science.aav6316
10.1038/nbt.2405
10.1016/j.pcad.2020.07.002
10.1093/jxb/ery453
10.1038/srep19792
10.1080/16549716.2019.1588513
10.1371/journal.pone.0175554
10.1186/s12937-018-0391-5
10.1371/journal.pone.0143497
10.1093/nutrit/nuaa063
10.1002/14651858.CD008524.pub3
10.1038/s41467-019-13993-7
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PublicationDate 2020-10-15
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  year: 2020
  text: 2020-10-15
  day: 15
PublicationDecade 2020
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PublicationTitle Nature communications
PublicationTitleAbbrev Nat Commun
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Nature Publishing Group
Nature Portfolio
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References Garg (CR6) 2018; 5
Li (CR46) 2015; 33
Bollinedi (CR38) 2019; 278
Low, Mwanga, Andrade, Carey, Ball (CR10) 2017; 14
De Lepeleire (CR47) 2018; 11
CR39
Storozhenko (CR45) 2007; 25
Strobbe, Van Der Straeten (CR44) 2017; 44
Lee (CR70) 2019; 99
CR32
Dong (CR62) 2020; 11
Blancquaert (CR50) 2015; 33
Fitzpatrick (CR2) 2012; 24
CR4
CR3
CR5
Bashir, Ishimaru, Nishizawa (CR29) 2010; 3
CR8
CR9
Gernand, Schulze, Stewart, West, Christian (CR61) 2016; 12
CR48
Paine (CR36) 2005; 23
Wu, Gruissem, Bhullar (CR33) 2019; 17
CR43
Flores, Vellozzi, Valencia, Sniezek (CR20) 2014; 26
CR42
Vos (CR17) 2016; 388
CR41
CR40
Li (CR52) 2012; 5
Mugode (CR51) 2014; 62
Che (CR56) 2016; 113
Black (CR18) 2013; 382
Ye (CR35) 2000; 287
Bouis, Saltzman (CR7) 2017; 12
Zou (CR34) 2019; 32
Bai (CR53) 2016; 14
CR16
Ishimaru, Bashir, Nishizawa (CR30) 2011; 4
CR15
CR59
Vanderschuren (CR72) 2012; 30
CR14
CR13
Swamy (CR37) 2019; 67
CR12
Alderman, Fernald (CR19) 2017; 37
Lee (CR73) 2018; 12
Beyene (CR63) 2018; 16
Joshi, Nayak (CR57) 2010; 5
Matveeva, Otten (CR74) 2019; 101
White, Broadley (CR1) 2009; 182
Singh, Gruissem, Bhullar (CR60) 2017; 7
Napier, Haslam, Tsalavouta, Sayanova (CR66) 2019; 5
De Steur, Demont, Gellynck, Stein (CR64) 2017; 44
Andersson, Saltzman, Virk, Pfeiffer (CR27) 2017; 17
De Moura (CR24) 2014; 5
De Steur (CR65) 2012; 29
Palmer (CR25) 2016; 146
CR28
Zaidi (CR68) 2019; 363
Sarrion-Perdigones (CR69) 2013; 162
Mangel (CR49) 2019; 99
de Cerqueira, Schafer, Fast, Herman (CR58) 2017; 8
CR26
CR23
CR22
CR21
Gayen, Ali, Sarkar, Datta, Datta (CR54) 2015; 242
Wirth (CR31) 2009; 7
Roberts (CR71) 2018; 3
Qaim (CR67) 2020; 42
Bailey, West, Black (CR11) 2015; 66
Zeng (CR55) 2015; 63
C Bai (19020_CR53) 2016; 14
L Mugode (19020_CR51) 2014; 62
RE Black (19020_CR18) 2013; 382
AL Flores (19020_CR20) 2014; 26
KT Li (19020_CR46) 2015; 33
K Lee (19020_CR70) 2019; 99
C Zou (19020_CR34) 2019; 32
SP Singh (19020_CR60) 2017; 7
TB Fitzpatrick (19020_CR2) 2012; 24
M Garg (19020_CR6) 2018; 5
19020_CR15
19020_CR59
19020_CR16
P Che (19020_CR56) 2016; 113
JW Low (19020_CR10) 2017; 14
19020_CR13
K Bashir (19020_CR29) 2010; 3
19020_CR14
19020_CR12
DTR de Cerqueira (19020_CR58) 2017; 8
H Vanderschuren (19020_CR72) 2012; 30
19020_CR3
J Wirth (19020_CR31) 2009; 7
D Gayen (19020_CR54) 2015; 242
19020_CR4
19020_CR5
HE Bouis (19020_CR7) 2017; 12
MS Andersson (19020_CR27) 2017; 17
19020_CR48
JA Paine (19020_CR36) 2005; 23
AC Palmer (19020_CR25) 2016; 146
19020_CR42
19020_CR43
19020_CR8
19020_CR40
19020_CR9
19020_CR41
H Alderman (19020_CR19) 2017; 37
FF De Moura (19020_CR24) 2014; 5
RL Bailey (19020_CR11) 2015; 66
H De Steur (19020_CR64) 2017; 44
A Sarrion-Perdigones (19020_CR69) 2013; 162
OX Dong (19020_CR62) 2020; 11
SSEA Zaidi (19020_CR68) 2019; 363
19020_CR39
H Bollinedi (19020_CR38) 2019; 278
TY Wu (19020_CR33) 2019; 17
AD Gernand (19020_CR61) 2016; 12
BPM Swamy (19020_CR37) 2019; 67
19020_CR32
RJ Roberts (19020_CR71) 2018; 3
PJ White (19020_CR1) 2009; 182
T Vos (19020_CR17) 2016; 388
JA Napier (19020_CR66) 2019; 5
S Strobbe (19020_CR44) 2017; 44
N Mangel (19020_CR49) 2019; 99
TV Matveeva (19020_CR74) 2019; 101
XD Ye (19020_CR35) 2000; 287
D Blancquaert (19020_CR50) 2015; 33
H De Steur (19020_CR65) 2012; 29
RK Joshi (19020_CR57) 2010; 5
S Storozhenko (19020_CR45) 2007; 25
19020_CR28
Y Ishimaru (19020_CR30) 2011; 4
L Li (19020_CR52) 2012; 5
19020_CR26
J Zeng (19020_CR55) 2015; 63
J De Lepeleire (19020_CR47) 2018; 11
19020_CR22
H Lee (19020_CR73) 2018; 12
19020_CR23
19020_CR21
G Beyene (19020_CR63) 2018; 16
M Qaim (19020_CR67) 2020; 42
References_xml – ident: CR22
– volume: 33
  start-page: 1029
  year: 2015
  end-page: 1032
  ident: CR46
  article-title: Increased bioavailable vitamin B-6 in field-grown transgenic cassava for dietary sufficiency
  publication-title: Nat. Biotechnol.
– volume: 99
  start-page: 1047
  year: 2019
  end-page: 1065
  ident: CR49
  article-title: Enhancement of vitamin B-6 levels in rice expressing vitamin B-6 biosynthesis de novo genes
  publication-title: Plant J.
  doi: 10.1111/tpj.14379
– volume: 8
  start-page: 149
  year: 2017
  end-page: 155
  ident: CR58
  article-title: Agronomic performance of insect-protected and herbicide-tolerant MON 89034 x TC1507 x NK603 x DAS-40278-9 corn is equivalent to that of conventional corn
  publication-title: GM Crops Food
  doi: 10.1080/21645698.2017.1301331
– volume: 66
  start-page: 22
  year: 2015
  end-page: 33
  ident: CR11
  article-title: The epidemiology of global micronutrient deficiencies
  publication-title: Ann. Nutr. Metab.
  doi: 10.1159/000371618
– volume: 29
  start-page: 432
  year: 2012
  end-page: 442
  ident: CR65
  article-title: Potential impact and cost-effectiveness of multi-biofortified rice in China
  publication-title: New Biotechnol.
  doi: 10.1016/j.nbt.2011.11.012
– volume: 11
  start-page: 175
  year: 2018
  end-page: 188
  ident: CR47
  article-title: Folate biofortification of potato by tuber-specific expression of four folate biosynthesis genes
  publication-title: Mol. Plant
  doi: 10.1016/j.molp.2017.12.008
– volume: 14
  start-page: 195
  year: 2016
  end-page: 205
  ident: CR53
  article-title: Bottlenecks in carotenoid biosynthesis and accumulation in rice endosperm are influenced by the precursor-product balance
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/pbi.12373
– volume: 242
  start-page: 353
  year: 2015
  end-page: 363
  ident: CR54
  article-title: Down-regulation of lipoxygenase gene reduces degradation of carotenoids of golden rice during storage
  publication-title: Planta
  doi: 10.1007/s00425-015-2314-4
– volume: 12
  start-page: 36
  year: 2018
  end-page: 45
  ident: CR73
  article-title: Capacity building for agricultural biotechnology in developing countries
  publication-title: Open Agric. J.
  doi: 10.2174/1874331501812010036
– ident: CR4
– volume: 7
  start-page: 718
  year: 2009
  end-page: 718
  ident: CR31
  article-title: Rice endosperm iron biofortification by targeted and synergistic action of nicotianamine synthase and ferritin
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/j.1467-7652.2009.00430.x
– ident: CR39
– ident: CR16
– ident: CR12
– volume: 17
  start-page: 11905
  year: 2017
  end-page: 11935
  ident: CR27
  article-title: Progress update: crop development of biofortified staple food crops under HarvestPlus
  publication-title: Afr. J. Food Agric. Nutr. Dev.
– ident: CR8
– volume: 278
  start-page: 773
  year: 2019
  end-page: 779
  ident: CR38
  article-title: Kinetics of beta-carotene degradation under different storage conditions in transgenic Golden Rice (R) lines
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2018.11.121
– ident: CR42
– volume: 5
  start-page: 339
  year: 2012
  end-page: 352
  ident: CR52
  article-title: The gene enhances carotenoid accumulation and stability during post-harvest storage of potato tubers
  publication-title: Mol. Plant
  doi: 10.1093/mp/ssr099
– volume: 3
  start-page: 61
  year: 2018
  end-page: 65
  ident: CR71
  article-title: The Nobel laureates’ campaign supporting GMOs
  publication-title: J. Innov. Knowl.
  doi: 10.1016/j.jik.2017.12.006
– volume: 44
  start-page: 202
  year: 2017
  end-page: 211
  ident: CR44
  article-title: Folate biofortification in food crops
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2016.12.003
– volume: 11
  start-page: 1
  year: 2020
  end-page: 10
  ident: CR62
  article-title: Marker-free carotenoid-enriched rice generated through targeted gene insertion using CRISPR-Cas9
  publication-title: Nat. Commun.
– ident: CR21
– volume: 24
  start-page: 395
  year: 2012
  end-page: 414
  ident: CR2
  article-title: Vitamin deficiencies in humans: can plant science help?
  publication-title: Plant Cell
  doi: 10.1105/tpc.111.093120
– volume: 101
  start-page: 415
  year: 2019
  end-page: 437
  ident: CR74
  article-title: Widespread occurrence of natural genetic transformation of plants by
  publication-title: Plant Mol. Biol.
  doi: 10.1007/s11103-019-00913-y
– volume: 67
  start-page: 7986
  year: 2019
  end-page: 7994
  ident: CR37
  article-title: Compositional analysis of genetically engineered GR2E “Golden Rice” in comparison to that of conventional rice
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.9b01524
– volume: 63
  start-page: 9083
  year: 2015
  end-page: 9092
  ident: CR55
  article-title: Metabolic engineering of wheat provitamin A by simultaneously overexpressing CrtB and silencing carotenoid hydroxylase (TaHYD)
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.5b04279
– volume: 146
  start-page: 2551
  year: 2016
  end-page: 2558
  ident: CR25
  article-title: Provitamin A carotenoid-biofortified maize consumption increases pupillary responsiveness among Zambian children in a randomized controlled trial
  publication-title: J. Nutr.
  doi: 10.3945/jn.116.239202
– ident: CR15
– volume: 382
  start-page: 427
  year: 2013
  end-page: 451
  ident: CR18
  article-title: Maternal and child undernutrition and overweight in low-income and middle-income countries
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)60937-X
– volume: 42
  start-page: 129
  year: 2020
  end-page: 150
  ident: CR67
  article-title: Role of new plant breeding technologies for food security and sustainable agricultural development
  publication-title: Appl. Econ. Perspect. Policy
  doi: 10.1002/aepp.13044
– volume: 26
  start-page: 3
  year: 2014
  end-page: 5
  ident: CR20
  article-title: Global burden of neural tube defects, risk factors, and prevention
  publication-title: Indian J. Community Health
– ident: CR9
– ident: CR32
– ident: CR5
– volume: 14
  start-page: 23
  year: 2017
  end-page: 30
  ident: CR10
  article-title: Tackling vitamin A deficiency with biofortified sweetpotato in sub-Saharan Africa
  publication-title: Glob. Food Sec.
  doi: 10.1016/j.gfs.2017.01.004
– volume: 388
  start-page: 1545
  year: 2016
  end-page: 1602
  ident: CR17
  article-title: Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990-2015: a systematic analysis for the global burden of disease study 2015
  publication-title: Lancet
  doi: 10.1016/S0140-6736(16)31678-6
– volume: 23
  start-page: 482
  year: 2005
  end-page: 487
  ident: CR36
  article-title: Improving the nutritional value of Golden Rice through increased pro-vitamin A content
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt1082
– volume: 5
  start-page: 563
  year: 2019
  end-page: 567
  ident: CR66
  article-title: The challenges of delivering genetically modified crops with nutritional enhancement traits
  publication-title: Nat. Plants
  doi: 10.1038/s41477-019-0430-z
– ident: CR26
– volume: 37
  start-page: 447
  year: 2017
  end-page: 476
  ident: CR19
  article-title: The nexus between nutrition and early childhood development
  publication-title: Annu. Rev. Nutr.
  doi: 10.1146/annurev-nutr-071816-064627
– volume: 99
  start-page: 317
  year: 2019
  end-page: 328
  ident: CR70
  article-title: CRISPR/Cas9-mediated targeted T-DNA integration in rice
  publication-title: Plant Mol. Biol.
  doi: 10.1007/s11103-018-00819-1
– volume: 32
  start-page: 854
  year: 2019
  end-page: 859
  ident: CR34
  article-title: Effects of foliar spraying of selenium fertilizer on yield, selenium content and heavy metals content in waxy maize
  publication-title: Southwest China J. Agric. Sci.
– ident: CR43
– volume: 182
  start-page: 49
  year: 2009
  end-page: 84
  ident: CR1
  article-title: Biofortification of crops with seven mineral elements often lacking in human diets - iron, zinc, copper, calcium, magnesium, selenium and iodine
  publication-title: New Phytol.
  doi: 10.1111/j.1469-8137.2008.02738.x
– ident: CR14
– volume: 25
  start-page: 1277
  year: 2007
  end-page: 1279
  ident: CR45
  article-title: Folate fortification of rice by metabolic engineering
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt1351
– volume: 3
  start-page: 122
  year: 2010
  end-page: 130
  ident: CR29
  article-title: Iron uptake and loading into rice grains
  publication-title: Rice
  doi: 10.1007/s12284-010-9042-y
– volume: 44
  start-page: 161
  year: 2017
  end-page: 168
  ident: CR64
  article-title: The social and economic impact of biofortification through genetic modification
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2017.01.012
– volume: 4
  start-page: 21
  year: 2011
  end-page: 27
  ident: CR30
  article-title: Zn uptake and translocation in rice plants
  publication-title: Rice
  doi: 10.1007/s12284-011-9061-3
– ident: CR40
– volume: 113
  start-page: 11040
  year: 2016
  end-page: 11045
  ident: CR56
  article-title: Elevated vitamin E content improves all-trans beta-carotene accumulation and stability in biofortified sorghum
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.1605689113
– ident: CR23
– volume: 5
  start-page: 568
  year: 2014
  end-page: 570
  ident: CR24
  article-title: Are biofortified staple food crops improving vitamin A and iron status in women and children? New evidence from efficacy trials
  publication-title: Adv. Nutr.
  doi: 10.3945/an.114.006627
– volume: 287
  start-page: 303
  year: 2000
  end-page: 305
  ident: CR35
  article-title: Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm
  publication-title: Science
  doi: 10.1126/science.287.5451.303
– ident: CR48
– volume: 33
  start-page: 1076
  year: 2015
  end-page: 1078
  ident: CR50
  article-title: Improving folate (vitamin B-9) stability in biofortified rice through metabolic engineering
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.3358
– volume: 12
  start-page: 49
  year: 2017
  end-page: 58
  ident: CR7
  article-title: Improving nutrition through biofortification: a review of evidence from HarvestPlus, 2003 through 2016
  publication-title: Glob. Food Sec.
  doi: 10.1016/j.gfs.2017.01.009
– ident: CR3
– volume: 16
  start-page: 1186
  year: 2018
  end-page: 1200
  ident: CR63
  article-title: Provitamin A biofortification of cassava enhances shelf life but reduces dry matter content of storage roots due to altered carbon partitioning into starch
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/pbi.12862
– volume: 62
  start-page: 6317
  year: 2014
  end-page: 6325
  ident: CR51
  article-title: Carotenoid retention of biofortified provitamin A maize ( .) after Zambian traditional methods of milling, cooking and storage
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf501233f
– volume: 5
  start-page: 12
  year: 2018
  ident: CR6
  article-title: Biofortified crops generated by breeding, agronomy and transgenic approaches are improving lives of millions of people around the world
  publication-title: Front. Nutr.
  doi: 10.3389/fnut.2018.00012
– ident: CR13
– volume: 5
  start-page: 51
  year: 2010
  end-page: 60
  ident: CR57
  article-title: Gene pyramiding-A broad spectrum technique for developing durable stress resistance in crops
  publication-title: Biotechnol. Mol. Biol. Rev.
– volume: 12
  start-page: 274
  year: 2016
  end-page: 289
  ident: CR61
  article-title: Micronutrient deficiencies in pregnancy worldwide: health effects and prevention
  publication-title: Nat. Rev. Endocrinol.
  doi: 10.1038/nrendo.2016.37
– volume: 17
  start-page: 9
  year: 2019
  end-page: 20
  ident: CR33
  article-title: Targeting intracellular transport combined with efficient uptake and storage significantly increases grain iron and zinc levels in rice
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/pbi.12943
– volume: 162
  start-page: 1618
  year: 2013
  end-page: 1631
  ident: CR69
  article-title: GoldenBraid 2.0: a comprehensive DNA assembly framework for plant synthetic biology
  publication-title: Plant Physiol.
  doi: 10.1104/pp.113.217661
– ident: CR59
– ident: CR28
– ident: CR41
– volume: 7
  start-page: 1
  year: 2017
  end-page: 11
  ident: CR60
  article-title: Single genetic locus improvement of iron, zinc and beta-carotene content in rice grains
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-016-0028-x
– volume: 363
  start-page: 1390
  year: 2019
  end-page: 1391
  ident: CR68
  article-title: New plant breeding technologies for food security
  publication-title: Science
  doi: 10.1126/science.aav6316
– volume: 30
  start-page: 1170
  year: 2012
  end-page: 1172
  ident: CR72
  article-title: Strengthening African R&D through effective transfer of tropical crop biotech to African institutions
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.2405
– volume: 67
  start-page: 7986
  year: 2019
  ident: 19020_CR37
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.9b01524
– ident: 19020_CR22
– volume: 5
  start-page: 568
  year: 2014
  ident: 19020_CR24
  publication-title: Adv. Nutr.
  doi: 10.3945/an.114.006627
– volume: 5
  start-page: 51
  year: 2010
  ident: 19020_CR57
  publication-title: Biotechnol. Mol. Biol. Rev.
– volume: 33
  start-page: 1029
  year: 2015
  ident: 19020_CR46
  publication-title: Nat. Biotechnol.
– volume: 12
  start-page: 49
  year: 2017
  ident: 19020_CR7
  publication-title: Glob. Food Sec.
  doi: 10.1016/j.gfs.2017.01.009
– ident: 19020_CR41
– ident: 19020_CR39
– ident: 19020_CR9
– ident: 19020_CR15
  doi: 10.1016/j.pcad.2020.07.002
– volume: 33
  start-page: 1076
  year: 2015
  ident: 19020_CR50
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.3358
– volume: 7
  start-page: 718
  year: 2009
  ident: 19020_CR31
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/j.1467-7652.2009.00430.x
– volume: 17
  start-page: 9
  year: 2019
  ident: 19020_CR33
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/pbi.12943
– ident: 19020_CR59
– volume: 287
  start-page: 303
  year: 2000
  ident: 19020_CR35
  publication-title: Science
  doi: 10.1126/science.287.5451.303
– volume: 37
  start-page: 447
  year: 2017
  ident: 19020_CR19
  publication-title: Annu. Rev. Nutr.
  doi: 10.1146/annurev-nutr-071816-064627
– volume: 3
  start-page: 122
  year: 2010
  ident: 19020_CR29
  publication-title: Rice
  doi: 10.1007/s12284-010-9042-y
– volume: 278
  start-page: 773
  year: 2019
  ident: 19020_CR38
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2018.11.121
– ident: 19020_CR48
  doi: 10.1093/jxb/ery453
– ident: 19020_CR32
  doi: 10.1038/srep19792
– volume: 182
  start-page: 49
  year: 2009
  ident: 19020_CR1
  publication-title: New Phytol.
  doi: 10.1111/j.1469-8137.2008.02738.x
– ident: 19020_CR23
– volume: 25
  start-page: 1277
  year: 2007
  ident: 19020_CR45
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt1351
– volume: 162
  start-page: 1618
  year: 2013
  ident: 19020_CR69
  publication-title: Plant Physiol.
  doi: 10.1104/pp.113.217661
– volume: 382
  start-page: 427
  year: 2013
  ident: 19020_CR18
  publication-title: Lancet
  doi: 10.1016/S0140-6736(13)60937-X
– volume: 62
  start-page: 6317
  year: 2014
  ident: 19020_CR51
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/jf501233f
– volume: 99
  start-page: 317
  year: 2019
  ident: 19020_CR70
  publication-title: Plant Mol. Biol.
  doi: 10.1007/s11103-018-00819-1
– volume: 5
  start-page: 12
  year: 2018
  ident: 19020_CR6
  publication-title: Front. Nutr.
  doi: 10.3389/fnut.2018.00012
– volume: 17
  start-page: 11905
  year: 2017
  ident: 19020_CR27
  publication-title: Afr. J. Food Agric. Nutr. Dev.
– volume: 5
  start-page: 339
  year: 2012
  ident: 19020_CR52
  publication-title: Mol. Plant
  doi: 10.1093/mp/ssr099
– volume: 101
  start-page: 415
  year: 2019
  ident: 19020_CR74
  publication-title: Plant Mol. Biol.
  doi: 10.1007/s11103-019-00913-y
– volume: 12
  start-page: 274
  year: 2016
  ident: 19020_CR61
  publication-title: Nat. Rev. Endocrinol.
  doi: 10.1038/nrendo.2016.37
– volume: 44
  start-page: 202
  year: 2017
  ident: 19020_CR44
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2016.12.003
– volume: 3
  start-page: 61
  year: 2018
  ident: 19020_CR71
  publication-title: J. Innov. Knowl.
  doi: 10.1016/j.jik.2017.12.006
– ident: 19020_CR12
– volume: 24
  start-page: 395
  year: 2012
  ident: 19020_CR2
  publication-title: Plant Cell
  doi: 10.1105/tpc.111.093120
– ident: 19020_CR13
  doi: 10.1080/16549716.2019.1588513
– volume: 7
  start-page: 1
  year: 2017
  ident: 19020_CR60
  publication-title: Sci. Rep.
  doi: 10.1038/s41598-016-0028-x
– volume: 66
  start-page: 22
  year: 2015
  ident: 19020_CR11
  publication-title: Ann. Nutr. Metab.
  doi: 10.1159/000371618
– volume: 12
  start-page: 36
  year: 2018
  ident: 19020_CR73
  publication-title: Open Agric. J.
  doi: 10.2174/1874331501812010036
– ident: 19020_CR3
– ident: 19020_CR5
  doi: 10.1371/journal.pone.0175554
– ident: 19020_CR43
– volume: 242
  start-page: 353
  year: 2015
  ident: 19020_CR54
  publication-title: Planta
  doi: 10.1007/s00425-015-2314-4
– volume: 29
  start-page: 432
  year: 2012
  ident: 19020_CR65
  publication-title: New Biotechnol.
  doi: 10.1016/j.nbt.2011.11.012
– ident: 19020_CR26
  doi: 10.1186/s12937-018-0391-5
– volume: 44
  start-page: 161
  year: 2017
  ident: 19020_CR64
  publication-title: Curr. Opin. Biotechnol.
  doi: 10.1016/j.copbio.2017.01.012
– volume: 11
  start-page: 175
  year: 2018
  ident: 19020_CR47
  publication-title: Mol. Plant
  doi: 10.1016/j.molp.2017.12.008
– volume: 113
  start-page: 11040
  year: 2016
  ident: 19020_CR56
  publication-title: Proc. Natl Acad. Sci. USA
  doi: 10.1073/pnas.1605689113
– volume: 30
  start-page: 1170
  year: 2012
  ident: 19020_CR72
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt.2405
– ident: 19020_CR4
  doi: 10.1371/journal.pone.0143497
– volume: 14
  start-page: 23
  year: 2017
  ident: 19020_CR10
  publication-title: Glob. Food Sec.
  doi: 10.1016/j.gfs.2017.01.004
– volume: 32
  start-page: 854
  year: 2019
  ident: 19020_CR34
  publication-title: Southwest China J. Agric. Sci.
– ident: 19020_CR40
– volume: 5
  start-page: 563
  year: 2019
  ident: 19020_CR66
  publication-title: Nat. Plants
  doi: 10.1038/s41477-019-0430-z
– ident: 19020_CR14
  doi: 10.1093/nutrit/nuaa063
– volume: 16
  start-page: 1186
  year: 2018
  ident: 19020_CR63
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/pbi.12862
– volume: 363
  start-page: 1390
  year: 2019
  ident: 19020_CR68
  publication-title: Science
  doi: 10.1126/science.aav6316
– volume: 146
  start-page: 2551
  year: 2016
  ident: 19020_CR25
  publication-title: J. Nutr.
  doi: 10.3945/jn.116.239202
– ident: 19020_CR21
– volume: 23
  start-page: 482
  year: 2005
  ident: 19020_CR36
  publication-title: Nat. Biotechnol.
  doi: 10.1038/nbt1082
– volume: 63
  start-page: 9083
  year: 2015
  ident: 19020_CR55
  publication-title: J. Agric. Food Chem.
  doi: 10.1021/acs.jafc.5b04279
– ident: 19020_CR42
– ident: 19020_CR8
– volume: 8
  start-page: 149
  year: 2017
  ident: 19020_CR58
  publication-title: GM Crops Food
  doi: 10.1080/21645698.2017.1301331
– ident: 19020_CR16
  doi: 10.1002/14651858.CD008524.pub3
– volume: 4
  start-page: 21
  year: 2011
  ident: 19020_CR30
  publication-title: Rice
  doi: 10.1007/s12284-011-9061-3
– volume: 11
  start-page: 1
  year: 2020
  ident: 19020_CR62
  publication-title: Nat. Commun.
  doi: 10.1038/s41467-019-13993-7
– volume: 388
  start-page: 1545
  year: 2016
  ident: 19020_CR17
  publication-title: Lancet
  doi: 10.1016/S0140-6736(16)31678-6
– ident: 19020_CR28
– volume: 14
  start-page: 195
  year: 2016
  ident: 19020_CR53
  publication-title: Plant Biotechnol. J.
  doi: 10.1111/pbi.12373
– volume: 99
  start-page: 1047
  year: 2019
  ident: 19020_CR49
  publication-title: Plant J.
  doi: 10.1111/tpj.14379
– volume: 42
  start-page: 129
  year: 2020
  ident: 19020_CR67
  publication-title: Appl. Econ. Perspect. Policy
  doi: 10.1002/aepp.13044
– volume: 26
  start-page: 3
  year: 2014
  ident: 19020_CR20
  publication-title: Indian J. Community Health
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Snippet Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited...
Biofortification is an effective means to reduce micronutrient malnutrition. Here, the authors review recent advances in biofortification and propose stacking...
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42/44
631/449/447/2311
631/61/318
631/61/447/8
706/1143
Biofortification - methods
Biotechnologie
Biotechnology
Breeding
Crops, Agricultural - genetics
Developing Countries
Food Supply
Food, Fortified
Global Health
Humanities and Social Sciences
Humans
Life sciences
Malnutrition - prevention & control
Metabolic Engineering - methods
Micronutrients
Minerals
multidisciplinary
Oryza
Perspective
Plants - genetics
Plants, Genetically Modified
Policy Making
Provitamins
Science
Science (multidisciplinary)
Sciences du vivant
Sustainable Development - economics
Sustainable Development - trends
Sustainable Development/economics/trends
United Nations
Vitamins
Title Multiplying the efficiency and impact of biofortification through metabolic engineering
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