Efficacy of a vaccine based on protective antigen and killed spores against experimental inhalational anthrax

Protective antigen (PA)-based anthrax vaccines acting on toxins are less effective than live attenuated vaccines, suggesting that additional antigens may contribute to protective immunity. Several reports indicate that capsule or spore-associated antigens may enhance the protection afforded by PA. A...

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Vydané v:	Infection and immunity Ročník 77; číslo 3; s. 1197
Hlavní autori:	Gauthier, Yves P, Tournier, Jean-Nicolas, Paucod, Jean-Charles, Corre, Jean-Philippe, Mock, Michèle, Goossens, Pierre L, Vidal, Dominique R
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 01.03.2009
Predmet:	Administration, Inhalation Administration, Intranasal Animals Anthrax - immunology Anthrax - prevention & control Anthrax Vaccines - administration & dosage Anthrax Vaccines - immunology Antibodies, Bacterial - blood Antibodies, Bacterial - immunology Antigens, Bacterial - administration & dosage Antigens, Bacterial - immunology Bacillus anthracis - immunology Disease Models, Animal Enzyme-Linked Immunosorbent Assay Guinea Pigs Injections, Subcutaneous Lung Diseases - immunology Lung Diseases - microbiology Lung Diseases - prevention & control Mice Spores, Bacterial - immunology
ISSN:	1098-5522, 1098-5522
On-line prístup:	Zistit podrobnosti o prístupe
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