Prevalence of Various Respiratory Viruses in the Middle Ear during Acute Otitis Media

Acute otitis media is the most common bacterial infection among children and the most frequent reason for outpatient antibiotic therapy. 1 Despite proper antibiotic treatment, middle-ear effusion may persist for weeks or months, 2 , 3 often resulting in repeated courses of antibiotics and, eventuall...

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Bibliographic Details
Published in:The New England journal of medicine Vol. 340; no. 4; pp. 260 - 264
Main Authors: Heikkinen, Terho, Thint, Monica, Chonmaitree, Tasnee
Format: Journal Article
Language:English
Published: Boston, MA Massachusetts Medical Society 28.01.1999
Subjects:
Acute Disease
Bacterial infections
Biological and medical sciences
Child
Child, Preschool
Ear diseases
Ear, auditive nerve, cochleovestibular tract, facial nerve: diseases, semeiology
Ear, Middle - microbiology
Ear, Middle - virology
Female
Humans
Infant
Male
Medical sciences
Nasal Lavage Fluid - microbiology
Nasal Lavage Fluid - virology
Non tumoral diseases
Orthomyxoviridae - isolation & purification
Otitis Media - drug therapy
Otitis Media - etiology
Otitis Media - microbiology
Otitis Media - virology
Otorhinolaryngology. Stomatology
parainfluenza virus
Prevalence
respiratory syncytial virus
Respiratory Syncytial Virus Infections - complications
Respiratory Syncytial Virus Infections - prevention & control
Respiratory Syncytial Viruses - isolation & purification
Respiratory Tract Infections - complications
Respiratory Tract Infections - virology
Respirovirus - isolation & purification
Studies
Vaccines
Viral infections
Viral Vaccines
Virus Diseases - epidemiology
Virus Diseases - virology
Viruses
Human
Prevalence
Respiratory disease
Pathogenesis
Middle ear disease
Acute
Vaccination
Respiratory system
Epidemiology
Infection
Viral disease
ENT disease
Otitis media
ISSN:0028-4793, 1533-4406
Online Access:Get full text
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Summary:Acute otitis media is the most common bacterial infection among children and the most frequent reason for outpatient antibiotic therapy. 1 Despite proper antibiotic treatment, middle-ear effusion may persist for weeks or months, 2 , 3 often resulting in repeated courses of antibiotics and, eventually, surgical intervention. 4 In the United States, the annual costs of otitis media have been estimated to exceed $3.5 billion. 5 Although acute otitis media is generally considered a bacterial infection, there is ample evidence that respiratory viruses have a crucial role in the etiology and pathogenesis of this disease. 6 , 7 Moreover, viruses may also profoundly affect the outcome of . . .
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199901283400402