Prevalence of Various Respiratory Viruses in the Middle Ear during Acute Otitis Media

Acute otitis media is the most common bacterial infection among children and the most frequent reason for outpatient antibiotic therapy. 1 Despite proper antibiotic treatment, middle-ear effusion may persist for weeks or months, 2 , 3 often resulting in repeated courses of antibiotics and, eventuall...

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Vydané v:The New England journal of medicine Ročník 340; číslo 4; s. 260 - 264
Hlavní autori: Heikkinen, Terho, Thint, Monica, Chonmaitree, Tasnee
Médium: Journal Article
Jazyk:English
Vydavateľské údaje: Boston, MA Massachusetts Medical Society 28.01.1999
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ISSN:0028-4793, 1533-4406
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Shrnutí:Acute otitis media is the most common bacterial infection among children and the most frequent reason for outpatient antibiotic therapy. 1 Despite proper antibiotic treatment, middle-ear effusion may persist for weeks or months, 2 , 3 often resulting in repeated courses of antibiotics and, eventually, surgical intervention. 4 In the United States, the annual costs of otitis media have been estimated to exceed $3.5 billion. 5 Although acute otitis media is generally considered a bacterial infection, there is ample evidence that respiratory viruses have a crucial role in the etiology and pathogenesis of this disease. 6 , 7 Moreover, viruses may also profoundly affect the outcome of . . .
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM199901283400402