A method for estimating vaccine-preventable pediatric influenza pneumonia hospitalizations in developing countries: Thailand as a case study

The burden of influenza in children is increasingly appreciated; some middle-income countries are considering support for influenza vaccine programs. To support decision-making, methods to estimate the potential impact of proposed programs are needed. Using Thailand as a case-study, we present a mod...

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Podrobná bibliografie
Vydáno v:	Vaccine Ročník 29; číslo 26; s. 4416 - 4421
Hlavní autoři:	Dawood, Fatimah S., Fry, Alicia M., Muangchana, Charung, Sanasuttipun, Wiwan, Baggett, Henry C., Chunsuttiwat, Supamit, Maloney, Susan A., Simmerman, James Mark
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Kidlington Elsevier Ltd 10.06.2011 Elsevier Elsevier Limited
Témata:	Allergy and Immunology Applied microbiology Biological and medical sciences case studies Child Child, Preschool children decision making Developing Countries Female Fundamental and applied biological sciences. Psychology Hospitalization - statistics & numerical data Humans Immunization Infant Influenza Influenza Vaccines - administration & dosage Influenza, Human - epidemiology Influenza, Human - prevention & control LDCs Microbiology Models, Biological monitoring pneumonia Pneumonia - epidemiology Pneumonia - prevention & control Pregnancy Thai people Thailand Thailand - epidemiology vaccination Vaccination - statistics & numerical data Vaccine Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Womens health Thailand Asia South east Asia Infant Vaccine Child Influenza Human Lung disease Pneumonia Respiratory disease Tropical zone Developing countries Method Infection Case study Viral disease
ISSN:	0264-410X, 1873-2518, 1873-2518
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Shrnutí:	The burden of influenza in children is increasingly appreciated; some middle-income countries are considering support for influenza vaccine programs. To support decision-making, methods to estimate the potential impact of proposed programs are needed. Using Thailand as a case-study, we present a model that uses surveillance data, published vaccine effectiveness estimates, and vaccination coverage assumptions to estimate the impact of influenza vaccination on pediatric influenza pneumonia hospitalizations. Approximately 56,000 influenza pneumonia hospitalizations occur annually among children aged <18 years in Thailand; 23,700 (41%) may be vaccine-preventable. Vaccination of 85% of Thai children aged 7 months–4 years might prevent 30% of all pediatric influenza pneumonia hospitalizations in Thailand.
Bibliografie:	http://dx.doi.org/10.1016/j.vaccine.2011.03.099 ObjectType-Case Study-2 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Feature-4 ObjectType-Report-1 ObjectType-Article-3 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
ISSN:	0264-410X 1873-2518 1873-2518
DOI:	10.1016/j.vaccine.2011.03.099