A method for estimating vaccine-preventable pediatric influenza pneumonia hospitalizations in developing countries: Thailand as a case study

The burden of influenza in children is increasingly appreciated; some middle-income countries are considering support for influenza vaccine programs. To support decision-making, methods to estimate the potential impact of proposed programs are needed. Using Thailand as a case-study, we present a mod...

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Bibliographic Details
Published in:Vaccine Vol. 29; no. 26; pp. 4416 - 4421
Main Authors: Dawood, Fatimah S., Fry, Alicia M., Muangchana, Charung, Sanasuttipun, Wiwan, Baggett, Henry C., Chunsuttiwat, Supamit, Maloney, Susan A., Simmerman, James Mark
Format: Journal Article
Language:English
Published: Kidlington Elsevier Ltd 10.06.2011
Elsevier
Elsevier Limited
Subjects:
Allergy and Immunology
Applied microbiology
Biological and medical sciences
case studies
Child
Child, Preschool
children
decision making
Developing Countries
Female
Fundamental and applied biological sciences. Psychology
Hospitalization - statistics & numerical data
Humans
Immunization
Infant
Influenza
Influenza Vaccines - administration & dosage
Influenza, Human - epidemiology
Influenza, Human - prevention & control
LDCs
Microbiology
Models, Biological
monitoring
pneumonia
Pneumonia - epidemiology
Pneumonia - prevention & control
Pregnancy
Thai people
Thailand
Thailand - epidemiology
vaccination
Vaccination - statistics & numerical data
Vaccine
Vaccines
Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
Womens health
Thailand
Asia
South east Asia
Infant
Vaccine
Child
Influenza
Human
Lung disease
Pneumonia
Respiratory disease
Tropical zone
Developing countries
Method
Infection
Case study
Viral disease
ISSN:0264-410X, 1873-2518, 1873-2518
Online Access:Get full text
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Description
Summary:The burden of influenza in children is increasingly appreciated; some middle-income countries are considering support for influenza vaccine programs. To support decision-making, methods to estimate the potential impact of proposed programs are needed. Using Thailand as a case-study, we present a model that uses surveillance data, published vaccine effectiveness estimates, and vaccination coverage assumptions to estimate the impact of influenza vaccination on pediatric influenza pneumonia hospitalizations. Approximately 56,000 influenza pneumonia hospitalizations occur annually among children aged <18 years in Thailand; 23,700 (41%) may be vaccine-preventable. Vaccination of 85% of Thai children aged 7 months–4 years might prevent 30% of all pediatric influenza pneumonia hospitalizations in Thailand.
Bibliography:http://dx.doi.org/10.1016/j.vaccine.2011.03.099
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ISSN:0264-410X
1873-2518
1873-2518
DOI:10.1016/j.vaccine.2011.03.099