Evidence for existence of an apoptosis‐inducing BH3‐only protein, sayonara, in Drosophila

Cells need to sense stresses to initiate the execution of the dormant cell death program. Since the discovery of the first BH3‐only protein Bad, BH3‐only proteins have been recognized as indispensable stress sensors that induce apoptosis. BH3‐only proteins have so far not been identified in Drosophi...

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Bibliographic Details
Published in:	The EMBO journal Vol. 42; no. 8; pp. e110454 - n/a
Main Authors:	Ikegawa, Yuko, Combet, Christophe, Groussin, Mathieu, Navratil, Vincent, Safar‐Remali, Sabrina, Shiota, Takuya, Aouacheria, Abdel, Yoo, Sa Kan
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 17.04.2023 Springer Nature B.V EMBO Press John Wiley and Sons Inc
Subjects:	Animals Apoptosis Apoptosis - physiology Autophagy BH3‐only protein Caspase Cell death Drosophila Drosophila - genetics Drosophila Proteins - metabolism EMBO07 Feedback Feedback loops Fruit flies Gene duplication Homology Insects Life Sciences Phylogeny Positive feedback Proteins Proto-Oncogene Proteins c-bcl-2 - metabolism Sensors BH3‐only protein apoptosis cell death caspase BH3-only protein Drosophila apoptosis BH3-only protein caspase cell death Drosophila Subject Categories Autophagy & Cell Death Drosophila Subject Categories Autophagy & Cell Death
ISSN:	0261-4189, 1460-2075, 1460-2075
Online Access:	Get full text
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