Genome-wide Analysis of Body Proportion Classifies Height-Associated Variants by Mechanism of Action and Implicates Genes Important for Skeletal Development

Human height is a composite measurement, reflecting the sum of leg, spine, and head lengths. Many common variants influence total height, but the effects of these or other variants on the components of height (body proportion) remain largely unknown. We studied sitting height ratio (SHR), the ratio...

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Vydáno v:	American journal of human genetics Ročník 96; číslo 5; s. 695
Hlavní autoři:	Chan, Yingleong, Salem, Rany M, Hsu, Yu-Han H, McMahon, George, Pers, Tune H, Vedantam, Sailaja, Esko, Tonu, Guo, Michael H, Lim, Elaine T, Franke, Lude, Smith, George Davey, Strachan, David P, Hirschhorn, Joel N
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 07.05.2015
Témata:	Adult Black or African American - genetics Body Height - genetics Chromosome Mapping Female Genome-Wide Association Study Humans Leg Bones - growth & development Male Middle Aged Multifactorial Inheritance - genetics Phenotype Polymorphism, Single Nucleotide White People - genetics
ISSN:	1537-6605, 1537-6605
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