Cancer stem cells and their niche in cancer progression and therapy

High recurrence and metastasis rates and poor prognoses are the major challenges of current cancer therapy. Mounting evidence suggests that cancer stem cells (CSCs) play an important role in cancer development, chemoradiotherapy resistance, recurrence, and metastasis. Therefore, targeted CSC therapy...

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Bibliographic Details
Published in:	Cancer cell international Vol. 23; no. 1; pp. 1 - 12
Main Authors:	Liu, Qiuping, Guo, Zongliang, Li, Guoyin, Zhang, Yunxia, Liu, Xiaomeng, Li, Bing, Wang, Jinping, Li, Xiaoyan
Format:	Journal Article
Language:	English
Published:	London BioMed Central 01.12.2023 Springer Nature B.V BMC
Subjects:	Angiogenesis Biomedical and Life Sciences Biomedicine Brain cancer Cancer Research cancer stem cells Cancer therapies Cell Biology Cellular components Chemoradiotherapy Chemotherapy Collagen CSC niche Cytokines Extracellular matrix Growth factors Hyaluronic acid Hypoxia Liver cancer Macrophages Mesenchymal stem cells Metastases Metastasis Prostate Radiation therapy Review Roles Stem cells Stromal cells Therapeutic strategies Tumor microenvironment Tumors Cellular components Extracellular matrix cancer stem cells CSC niche Therapeutic strategies
ISSN:	1475-2867, 1475-2867
Online Access:	Get full text
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