Endoplasmic reticulum dysfunction in neurological disease

Endoplasmic reticulum (ER) dysfunction might have an important part to play in a range of neurological disorders, including cerebral ischaemia, sleep apnoea, Alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, the prion diseases, and familial encephalopathy with neuroserpin...

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Bibliographic Details
Published in:	Lancet neurology Vol. 12; no. 1; pp. 105 - 118
Main Authors:	Roussel, Benoit D, Kruppa, Antonina J, Miranda, Elena, Crowther, Damian C, Lomas, David A, Marciniak, Stefan J
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.01.2013 Elsevier Limited Elsevier
Subjects:	Alzheimer's disease Amyloid beta-Peptides Amyloid beta-Peptides - genetics Amyotrophic lateral sclerosis Animals Ataxia beta -Amyloid Cellular Biology Cognitive ability Disease Endoplasmic Reticulum Endoplasmic Reticulum - pathology Endoplasmic Reticulum - physiology Enzymes Epilepsy Humans Inclusion bodies Ischemia Life Sciences Movement disorders Multiple sclerosis Mutation Nervous System Diseases Nervous System Diseases - genetics Nervous System Diseases - pathology Nervous System Diseases - physiopathology Neurodegenerative diseases Neurological diseases Neurology neuroserpin Prion protein Protein Folding Reperfusion Signal Transduction Signal Transduction - physiology Sleep Sleep disorders Stress Stroke Unfolded Protein Response Unfolded Protein Response - genetics
ISSN:	1474-4422, 1474-4465, 1474-4465
Online Access:	Get full text
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