Rationale and validation of a novel mobile application probing motor inhibition: Proof of concept of CALM-IT
Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies on rigorous, time-intensive, clinic-based laboratory research, making it difficult to translate research paradigms into tools that can be used...
Gespeichert in:
| Veröffentlicht in: | PloS one Jg. 16; H. 6; S. e0252245 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
San Francisco, CA USA
Public Library of Science
04.06.2021
Public Library of Science (PLoS) |
| Schlagworte: | |
| ISSN: | 1932-6203, 1932-6203 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies on rigorous, time-intensive, clinic-based laboratory research, making it difficult to translate research paradigms into tools that can be used by clinicians in the community. The broad adoption of smartphone technology provides a promising opportunity to bridge the gap between the mechanisms identified in the laboratory and the clinical interventions targeting them in the community. The goal of the current study is to develop a developmentally appropriate, engaging, novel mobile application called CALM-IT that probes a narrow biologically informed process, inhibitory control. We aim to leverage the rigorous and robust methods traditionally used in laboratory settings to validate this novel mechanism-driven but easily disseminatable tool that can be used by clinicians to probe inhibitory control in the community. The development of CALM-IT has significant implications for the ability to screen for inhibitory control deficits in the community by both clinicians and researchers. By facilitating assessment of inhibitory control outside of the laboratory setting, researchers could have access to larger and more diverse samples. Additionally, in the clinical setting, CALM-IT represents a novel clinical screening measure that could be used to determine personalized courses of treatment based on the presence of inhibitory control deficits. |
|---|---|
| AbstractList | Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies on rigorous, time-intensive, clinic-based laboratory research, making it difficult to translate research paradigms into tools that can be used by clinicians in the community. The broad adoption of smartphone technology provides a promising opportunity to bridge the gap between the mechanisms identified in the laboratory and the clinical interventions targeting them in the community. The goal of the current study is to develop a developmentally appropriate, engaging, novel mobile application called CALM-IT that probes a narrow biologically informed process, inhibitory control. We aim to leverage the rigorous and robust methods traditionally used in laboratory settings to validate this novel mechanism-driven but easily disseminatable tool that can be used by clinicians to probe inhibitory control in the community. The development of CALM-IT has significant implications for the ability to screen for inhibitory control deficits in the community by both clinicians and researchers. By facilitating assessment of inhibitory control outside of the laboratory setting, researchers could have access to larger and more diverse samples. Additionally, in the clinical setting, CALM-IT represents a novel clinical screening measure that could be used to determine personalized courses of treatment based on the presence of inhibitory control deficits. Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies on rigorous, time-intensive, clinic-based laboratory research, making it difficult to translate research paradigms into tools that can be used by clinicians in the community. The broad adoption of smartphone technology provides a promising opportunity to bridge the gap between the mechanisms identified in the laboratory and the clinical interventions targeting them in the community. The goal of the current study is to develop a developmentally appropriate, engaging, novel mobile application called CALM-IT that probes a narrow biologically informed process, inhibitory control. We aim to leverage the rigorous and robust methods traditionally used in laboratory settings to validate this novel mechanism-driven but easily disseminatable tool that can be used by clinicians to probe inhibitory control in the community. The development of CALM-IT has significant implications for the ability to screen for inhibitory control deficits in the community by both clinicians and researchers. By facilitating assessment of inhibitory control outside of the laboratory setting, researchers could have access to larger and more diverse samples. Additionally, in the clinical setting, CALM-IT represents a novel clinical screening measure that could be used to determine personalized courses of treatment based on the presence of inhibitory control deficits.Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies on rigorous, time-intensive, clinic-based laboratory research, making it difficult to translate research paradigms into tools that can be used by clinicians in the community. The broad adoption of smartphone technology provides a promising opportunity to bridge the gap between the mechanisms identified in the laboratory and the clinical interventions targeting them in the community. The goal of the current study is to develop a developmentally appropriate, engaging, novel mobile application called CALM-IT that probes a narrow biologically informed process, inhibitory control. We aim to leverage the rigorous and robust methods traditionally used in laboratory settings to validate this novel mechanism-driven but easily disseminatable tool that can be used by clinicians to probe inhibitory control in the community. The development of CALM-IT has significant implications for the ability to screen for inhibitory control deficits in the community by both clinicians and researchers. By facilitating assessment of inhibitory control outside of the laboratory setting, researchers could have access to larger and more diverse samples. Additionally, in the clinical setting, CALM-IT represents a novel clinical screening measure that could be used to determine personalized courses of treatment based on the presence of inhibitory control deficits. |
| Audience | Academic |
| Author | Haller, Simone P. Bezek, Jessica German, Ramaris Botz-Zapp, Christian Jangraw, David C. Naim, Reut Brotman, Melissa A. Cardinale, Elise M. |
| AuthorAffiliation | 1 Emotion & Development Branch, National Institute of Mental Health, Bethesda, MD, United States of America 2 Department of Electrical and Biomedical Engineering, University of Vermont, Burlington, VT, United States of America Brunel University London, UNITED KINGDOM |
| AuthorAffiliation_xml | – name: 1 Emotion & Development Branch, National Institute of Mental Health, Bethesda, MD, United States of America – name: 2 Department of Electrical and Biomedical Engineering, University of Vermont, Burlington, VT, United States of America – name: Brunel University London, UNITED KINGDOM |
| Author_xml | – sequence: 1 givenname: Elise M. orcidid: 0000-0002-5117-6124 surname: Cardinale fullname: Cardinale, Elise M. – sequence: 2 givenname: Reut surname: Naim fullname: Naim, Reut – sequence: 3 givenname: Simone P. surname: Haller fullname: Haller, Simone P. – sequence: 4 givenname: Ramaris surname: German fullname: German, Ramaris – sequence: 5 givenname: Christian surname: Botz-Zapp fullname: Botz-Zapp, Christian – sequence: 6 givenname: Jessica surname: Bezek fullname: Bezek, Jessica – sequence: 7 givenname: David C. orcidid: 0000-0002-2470-7647 surname: Jangraw fullname: Jangraw, David C. – sequence: 8 givenname: Melissa A. surname: Brotman fullname: Brotman, Melissa A. |
| BookMark | eNqNkluLEzEYhgdZcQ_6D7wYEEQvWnOaZLoXwrJ4KKysrKu3IZNDm5ImY5Ip-u_NtEV2REQSSPi-530hX97z6sQHr6vqOQRziBl8swlD9MLN-1KeA9QgRJpH1RlcYDSjCOCTB_fT6jylDQANbil9Up1iAlrKUHtWuTuRbSg-uhZe1TvhrNpX6mBqUfuw067ehs6OQN87Kw_dPpaaX5VWDrG2fm07OzYu688xFGnZMnip-zxer69uPs2W90-rx0a4pJ8dz4vq6_t399cfZze3H5aFmUkKWZ4p1eEFxE0rBe0IBMhQaTDrAIbICN01tMUEKmmAEG2LVEsYBJBQYxDuGJP4oloefFUQG95HuxXxJw_C8n0hxBUXMVvpNO9axZQiAhvUEaGhUBpQs4Bo0VEDjS5ebw9e_dBttZLa5yjcxHTa8XbNV2HHW8gYxbAYvDoaxPB90CnzrU1SOye8DkPiqMGFwwyQgr44oKvyH9x6E4qjHHF-RSkpIyEUFGr-F6ospbe2DF2b8llTweuJoDBZ_8grMaTEl1_u_p-9_TZlXz5g11q4vE7BDWMO0hQkB1DGkFLU5vf4IOBjmPkxzHwMMz-Gucgu_5BJm_fxKw-27t_iXw6x_c8 |
| CitedBy_id | crossref_primary_10_1007_s11920_022_01390_9 crossref_primary_10_29121_granthaalayah_v13_i6_2025_6234 crossref_primary_10_2196_51125 crossref_primary_10_1371_journal_pone_0319004 |
| Cites_doi | 10.1016/j.tics.2013.12.003 10.1037/0012-1649.35.1.205 10.1093/cercor/10.3.252 10.1001/jamapsychiatry.2014.426 10.3758/BF03207704 10.1027/1618-3169.56.1.48 10.1176/appi.ajp.2017.16040400 10.1177/0963721410370293 10.1037/pas0000664 10.1016/j.paid.2006.01.011 10.1146/annurev-clinpsy-032816-044941 10.3389/fnhum.2013.00466 10.1176/appi.ajp.2014.13091213 10.1002/mpr.1411 10.1002/da.22937 10.1016/j.bandc.2004.09.016 10.1097/00004583-199704000-00018 10.1080/15374416.2015.1038827 10.17744/mehc.38.2.02 10.1001/archpsyc.55.1.56 10.1017/S0954579419000300 10.1016/j.jaac.2019.11.028 10.1016/S2215-0366(17)30513-8 10.1016/j.pbb.2013.08.007 10.1001/jamapsychiatry.2018.0468 10.1037/0033-2909.86.2.420 10.1016/j.biopsych.2005.02.006 10.1111/1467-7687.00235 10.17744/1040-2861-37.3.206 10.1111/j.1467-8624.2004.00745.x 10.1056/NEJMc1916446 10.1111/j.1469-7610.2012.02561.x 10.1016/j.biopsych.2006.08.042 10.1080/16506073.2016.1143201 10.21105/joss.00470 10.1016/j.tics.2017.02.002 10.1146/annurev-neuro-071714-034054 10.1111/j.1469-8986.2006.00403.x 10.1080/13506289508401726 10.1016/0042-6989(78)90218-3 10.1016/j.biopsych.2004.10.026 10.1016/j.cortex.2016.04.023 10.1111/j.1469-7610.2007.01751.x 10.1037/0096-3445.117.1.34 10.1007/978-0-387-79948-3_1536 10.1126/scitranslmed.3003142 10.1146/annurev.clinpsy.3.022806.091415 10.1111/j.1749-6632.2012.06751.x 10.2196/13834 10.1037/0033-2909.126.2.220 10.1016/0001-6918(69)90065-1 10.1002/wps.20227 10.1001/jamapsychiatry.2016.3282 10.1016/j.pneurobio.2013.06.005 10.1016/j.jcm.2016.02.012 10.1097/00004583-199707000-00021 10.1001/archpsyc.1977.01770170081007 10.1037/1528-3542.7.2.336 10.1016/j.neuroimage.2013.11.001 10.1016/j.jad.2016.09.016 10.1007/s00213-008-1127-6 10.1017/S0954579419000671 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2021 Public Library of Science |
| Copyright_xml | – notice: COPYRIGHT 2021 Public Library of Science |
| DBID | AAYXX CITATION IOV ISR 7X8 5PM DOA |
| DOI | 10.1371/journal.pone.0252245 |
| DatabaseName | CrossRef Gale In Context: Opposing Viewpoints Gale In Context: Science MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE - Academic |
| DatabaseTitleList | CrossRef MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Sciences (General) |
| DocumentTitleAlternate | Rationale and validation of novel inhibitory control mobile application |
| EISSN | 1932-6203 |
| ExternalDocumentID | oai_doaj_org_article_b8d7dd4a3f2b4ae1ade06f9129b6f1fe PMC8177631 A664135460 10_1371_journal_pone_0252245 |
| GeographicLocations | United States |
| GeographicLocations_xml | – name: United States |
| GrantInformation_xml | – fundername: ; grantid: Intramural Funding |
| GroupedDBID | --- 123 29O 2WC 53G 5VS 7RV 7X2 7X7 7XC 88E 8AO 8C1 8CJ 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ AAUCC AAWOE AAYXX ABDBF ABIVO ABJCF ABUWG ACCTH ACGFO ACIHN ACIWK ACPRK ACUHS ADBBV AEAQA AENEX AEUYN AFFHD AFKRA AFPKN AFRAH AHMBA ALMA_UNASSIGNED_HOLDINGS AOIJS APEBS ARAPS ATCPS BAIFH BAWUL BBNVY BBTPI BCNDV BENPR BGLVJ BHPHI BKEYQ BPHCQ BVXVI BWKFM CCPQU CITATION CS3 D1I D1J D1K DIK DU5 E3Z EAP EAS EBD EMOBN ESX EX3 F5P FPL FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IEA IGS IHR IHW INH INR IOV IPY ISE ISR ITC K6- KB. KQ8 L6V LK5 LK8 M0K M1P M48 M7P M7R M7S M~E NAPCQ O5R O5S OK1 OVT P2P P62 PATMY PDBOC PHGZM PHGZT PIMPY PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PTHSS PV9 PYCSY RNS RPM RZL SV3 TR2 UKHRP WOQ WOW ~02 ~KM ALIPV BBORY 7X8 ESTFP PUEGO 5PM |
| ID | FETCH-LOGICAL-c617t-ddb391358ca6b4102f6cf37b0312faeb568341dcf0aa882d84710146ff23b77c3 |
| IEDL.DBID | DOA |
| ISICitedReferencesCount | 3 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000664640100041&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1932-6203 |
| IngestDate | Fri Oct 03 12:44:17 EDT 2025 Tue Nov 04 01:43:34 EST 2025 Sun Sep 28 11:10:40 EDT 2025 Sat Nov 29 13:11:27 EST 2025 Sat Nov 29 09:56:04 EST 2025 Wed Nov 26 09:53:27 EST 2025 Wed Nov 26 10:14:21 EST 2025 Thu May 22 20:33:10 EDT 2025 Sat Nov 29 02:41:17 EST 2025 Tue Nov 18 20:57:44 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Language | English |
| License | This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c617t-ddb391358ca6b4102f6cf37b0312faeb568341dcf0aa882d84710146ff23b77c3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 Competing Interests: The authors have declared that no competing interests exist. |
| ORCID | 0000-0002-5117-6124 0000-0002-2470-7647 |
| OpenAccessLink | https://doaj.org/article/b8d7dd4a3f2b4ae1ade06f9129b6f1fe |
| PMID | 34086728 |
| PQID | 2537633704 |
| PQPubID | 23479 |
| PageCount | e0252245 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_b8d7dd4a3f2b4ae1ade06f9129b6f1fe pubmedcentral_primary_oai_pubmedcentral_nih_gov_8177631 proquest_miscellaneous_2537633704 gale_infotracmisc_A664135460 gale_infotracacademiconefile_A664135460 gale_incontextgauss_ISR_A664135460 gale_incontextgauss_IOV_A664135460 gale_healthsolutions_A664135460 crossref_primary_10_1371_journal_pone_0252245 crossref_citationtrail_10_1371_journal_pone_0252245 |
| PublicationCentury | 2000 |
| PublicationDate | 2021-06-04 |
| PublicationDateYYYYMMDD | 2021-06-04 |
| PublicationDate_xml | – month: 06 year: 2021 text: 2021-06-04 day: 04 |
| PublicationDecade | 2020 |
| PublicationPlace | San Francisco, CA USA |
| PublicationPlace_xml | – name: San Francisco, CA USA |
| PublicationTitle | PloS one |
| PublicationYear | 2021 |
| Publisher | Public Library of Science Public Library of Science (PLoS) |
| Publisher_xml | – name: Public Library of Science – name: Public Library of Science (PLoS) |
| References | B Luna (pone.0252245.ref020) 2015; 38 AR Aron (pone.0252245.ref026) 2005; 57 pone.0252245.ref064 M Peverill (pone.0252245.ref054) 2017 EM Cardinale (pone.0252245.ref059) 2019 B Luna (pone.0252245.ref013) 2004; 75 M Ferrari (pone.0252245.ref056) 2020; 9 CW Eriksen (pone.0252245.ref030) 1995; 2 EM Cardinale (pone.0252245.ref047) 2019; 31 NC Venables (pone.0252245.ref025) 2018 J Stoddard (pone.0252245.ref062) 2017; 74 JG Snodgrass (pone.0252245.ref071) 1988; 117 E Leibenluft (pone.0252245.ref041) 2017; 21 H Stanislaw (pone.0252245.ref072) 1999; 31 J Posner (pone.0252245.ref038) 2014 J Joormann (pone.0252245.ref009) 2010; 19 PMG Emmelkamp (pone.0252245.ref058) 2014; 23 J Kaufman (pone.0252245.ref063) 1997; 36 SP Haller (pone.0252245.ref066) 2020 EG Willcutt (pone.0252245.ref052) 2005; 57 AR Aron (pone.0252245.ref016) 2014; 18 N Derakshan (pone.0252245.ref007) 2009; 56 TP Beauchaine (pone.0252245.ref033) 2015; 44 KR Ridderinkhof (pone.0252245.ref027) 2004; 56 TK Koo (pone.0252245.ref074) 2016; 15 MB Powers (pone.0252245.ref057) 2016; 45 EA Holmes (pone.0252245.ref053) 2018; 5 PE Shrout (pone.0252245.ref075) 1979; 86 B Birmaher (pone.0252245.ref068) 1997; 36 TA Field (pone.0252245.ref005) 2015; 37 W-L Tseng (pone.0252245.ref051) 2018; 1 JT Nigg (pone.0252245.ref010) 2000; 126 MA Brotman (pone.0252245.ref043) 2006; 60 SL Karalunas (pone.0252245.ref040) 2019; 31 DM Eagle (pone.0252245.ref017) 2008; 199 LM McTeague (pone.0252245.ref014) 2017; 174 O Eyre (pone.0252245.ref045) 2019 K Kircanski (pone.0252245.ref060) 2017; 216 FC Donders (pone.0252245.ref029) 1969; 30 MW Eysenck (pone.0252245.ref048) 2007; 7 B Chaarani (pone.0252245.ref050) 2020; 59 MA Brotman (pone.0252245.ref037) 2017; 13 WE Copeland (pone.0252245.ref044) 2014; 171 C Conners (pone.0252245.ref069) 2011 J Gordon (pone.0252245.ref001) 2020; 382 PG Enticott (pone.0252245.ref022) 2006; 41 DS Pine (pone.0252245.ref046) 1998; 55 K Kircanski (pone.0252245.ref061) 2018; 75 TR Insel (pone.0252245.ref004) 2014; 71 SF Logue (pone.0252245.ref024) 2014; 123 NP Friedman (pone.0252245.ref015) 2017; 86 K Towbin (pone.0252245.ref039) 2019 BR Williams (pone.0252245.ref021) 1999; 35 A Stringaris (pone.0252245.ref067) 2012; 53 TR Insel (pone.0252245.ref003) 2015; 14 JS Moser (pone.0252245.ref049) 2013; 7 AR Smith (pone.0252245.ref011) 2019; 36 S Shiffman (pone.0252245.ref012) 2008; 4 P Cuijpers (pone.0252245.ref055) 2018 A Ancold (pone.0252245.ref070) 1995 SE Hyman (pone.0252245.ref002) 2012; 4 TP Beauchaine (pone.0252245.ref034) 2019; 31 CM Deveney (pone.0252245.ref008) 2018 A Bari (pone.0252245.ref065) 2013; 108 DS Pine (pone.0252245.ref042) 2007; 48 R Miller (pone.0252245.ref006) 2016; 38 S Durston (pone.0252245.ref019) 2002; 5 SB Hutton (pone.0252245.ref023) 2006; 43 PE Hallett (pone.0252245.ref028) 1978; 18 GD Logan (pone.0252245.ref031) 1984; 10 AC Roberts (pone.0252245.ref018) 2000; 10 J Rutschmann (pone.0252245.ref032) 1977; 34 KN Ochsner (pone.0252245.ref036) 2012; 1251 D Makowski (pone.0252245.ref073) 2018; 3 N Kohn (pone.0252245.ref035) 2014; 87 |
| References_xml | – volume: 18 start-page: 177 year: 2014 ident: pone.0252245.ref016 article-title: Inhibition and the right inferior frontal cortex: one decade on publication-title: Trends in Cognitive Sciences doi: 10.1016/j.tics.2013.12.003 – year: 2014 ident: pone.0252245.ref038 article-title: Using Stimulants to Treat ADHD-Related Emotional Lability publication-title: Current Psychiatry Reports – year: 2018 ident: pone.0252245.ref008 article-title: Temporally sensitive neural measures of inhibition in preschool children across a spectrum of irritability publication-title: Developmental Psychobiology – volume: 35 start-page: 205 year: 1999 ident: pone.0252245.ref021 article-title: Development of Inhibitory Control Across the Life Span publication-title: Developmental Psychology doi: 10.1037/0012-1649.35.1.205 – volume: 10 start-page: 252 year: 2000 ident: pone.0252245.ref018 article-title: Inhibitory Control and Affective Processing in the Prefrontal Cortex: Neuropsychological Studies in the Common Marmoset publication-title: Cerebral Cortex doi: 10.1093/cercor/10.3.252 – start-page: 237 year: 1995 ident: pone.0252245.ref070 article-title: Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents publication-title: International Journal of Methods in Psychiatric Research – volume: 71 start-page: 745 year: 2014 ident: pone.0252245.ref004 article-title: National Institute of Mental Health Clinical Trials: New Opportunities, New Expectations publication-title: JAMA Psychiatry doi: 10.1001/jamapsychiatry.2014.426 – volume: 31 start-page: 137 year: 1999 ident: pone.0252245.ref072 article-title: Calculation of signal detection theory measures publication-title: Behavior Research Methods, Instruments, & Computers doi: 10.3758/BF03207704 – volume: 56 start-page: 48 year: 2009 ident: pone.0252245.ref007 article-title: Anxiety, Inhibition, Efficiency, and Effectiveness: An Investigation Using the Antisaccade Task. publication-title: Experimental Psychology doi: 10.1027/1618-3169.56.1.48 – volume: 174 start-page: 676 year: 2017 ident: pone.0252245.ref014 article-title: Identification of Common Neural Circuit Disruptions in Cognitive Control Across Psychiatric Disorders publication-title: American Journal of Psychiatry doi: 10.1176/appi.ajp.2017.16040400 – volume: 19 start-page: 161 year: 2010 ident: pone.0252245.ref009 article-title: Cognitive Inhibition and Emotion Regulation in Depression publication-title: Current Directions in Psychological Science doi: 10.1177/0963721410370293 – ident: pone.0252245.ref064 – volume: 31 start-page: 236 year: 2019 ident: pone.0252245.ref040 article-title: Do we need an irritable subtype of ADHD? Replication and extension of a promising temperament profile approach to ADHD subtyping publication-title: Psychological Assessment doi: 10.1037/pas0000664 – volume: 41 start-page: 285 year: 2006 ident: pone.0252245.ref022 article-title: Associations between laboratory measures of executive inhibitory control and self-reported impulsivity publication-title: Personality and Individual Differences doi: 10.1016/j.paid.2006.01.011 – volume: 13 start-page: 317 year: 2017 ident: pone.0252245.ref037 article-title: Irritability in Children and Adolescents. publication-title: Annual Review of Clinical Psychology doi: 10.1146/annurev-clinpsy-032816-044941 – volume: 7 year: 2013 ident: pone.0252245.ref049 article-title: On the relationship between anxiety and error monitoring: a meta-analysis and conceptual framework publication-title: Frontiers in Human Neuroscience doi: 10.3389/fnhum.2013.00466 – volume: 171 start-page: 668 year: 2014 ident: pone.0252245.ref044 article-title: Adult Diagnostic and Functional Outcomes of DSM-5 Disruptive Mood Dysregulation Disorder publication-title: American Journal of Psychiatry doi: 10.1176/appi.ajp.2014.13091213 – volume: 23 start-page: 58 year: 2014 ident: pone.0252245.ref058 article-title: Advancing psychotherapy and evidence-based psychological interventions: Advancing psychotherapy publication-title: International Journal of Methods in Psychiatric Research doi: 10.1002/mpr.1411 – volume: 36 start-page: 701 year: 2019 ident: pone.0252245.ref011 article-title: Advancing clinical neuroscience through enhanced tools: Pediatric social anxiety as an example publication-title: Depression and Anxiety doi: 10.1002/da.22937 – volume: 56 start-page: 129 year: 2004 ident: pone.0252245.ref027 article-title: Neurocognitive mechanisms of cognitive control: The role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning publication-title: Brain and Cognition doi: 10.1016/j.bandc.2004.09.016 – volume: 36 start-page: 545 year: 1997 ident: pone.0252245.ref068 article-title: The Screen for Child Anxiety Related Emotional Disorders (SCARED): Scale Construction and Psychometric Characteristics publication-title: Journal of the American Academy of Child & Adolescent Psychiatry doi: 10.1097/00004583-199704000-00018 – start-page: 1 year: 2018 ident: pone.0252245.ref025 article-title: Quantifying Inhibitory Control as Externalizing Proneness: A Cross-Domain Model publication-title: Clinical Psychological Science – volume: 44 start-page: 875 year: 2015 ident: pone.0252245.ref033 article-title: Future Directions in Emotion Dysregulation and Youth Psychopathology publication-title: Journal of Clinical Child & Adolescent Psychology doi: 10.1080/15374416.2015.1038827 – volume: 38 start-page: 103 year: 2016 ident: pone.0252245.ref006 article-title: Neuroeducation: Integrating Brain-Based Psychoeducation into Clinical Practice publication-title: Journal of Mental Health Counseling doi: 10.17744/mehc.38.2.02 – volume: 55 start-page: 56 year: 1998 ident: pone.0252245.ref046 article-title: The Risk for Early-Adulthood Anxiety and Depressive Disorders in Adolescents With Anxiety and Depressive Disorders publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.55.1.56 – volume: 31 start-page: 859 year: 2019 ident: pone.0252245.ref047 article-title: Inhibitory control and emotion dysregulation: A framework for research on anxiety publication-title: Development and Psychopathology doi: 10.1017/S0954579419000300 – volume: 59 start-page: 1371 year: 2020 ident: pone.0252245.ref050 article-title: Neural Correlates of Adolescent Irritability and Its Comorbidity With Psychiatric Disorders publication-title: Journal of the American Academy of Child & Adolescent Psychiatry doi: 10.1016/j.jaac.2019.11.028 – volume: 5 start-page: 237 year: 2018 ident: pone.0252245.ref053 article-title: The Lancet Psychiatry Commission on psychological treatments research in tomorrow’s science publication-title: The Lancet Psychiatry doi: 10.1016/S2215-0366(17)30513-8 – start-page: 1 year: 2019 ident: pone.0252245.ref059 article-title: Parsing neurodevelopmental features of irritability and anxiety: Replication and validation of a latent variable approach publication-title: Development and Psychopathology – volume: 123 start-page: 45 year: 2014 ident: pone.0252245.ref024 article-title: The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition publication-title: Pharmacology Biochemistry and Behavior doi: 10.1016/j.pbb.2013.08.007 – volume: 75 start-page: 631 year: 2018 ident: pone.0252245.ref061 article-title: A Latent Variable Approach to Differentiating Neural Mechanisms of Irritability and Anxiety in Youth publication-title: JAMA Psychiatry doi: 10.1001/jamapsychiatry.2018.0468 – volume: 86 start-page: 420 year: 1979 ident: pone.0252245.ref075 article-title: Intraclass Correlations: Uses in Assessing Rater Reliability publication-title: Psychological bulletin doi: 10.1037/0033-2909.86.2.420 – year: 2019 ident: pone.0252245.ref045 article-title: Irritability in ADHD: association with later depression symptoms. publication-title: European Child & Adolescent Psychiatry – volume: 57 start-page: 1336 year: 2005 ident: pone.0252245.ref052 article-title: Validity of the Executive Function Theory of Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review publication-title: Biological Psychiatry doi: 10.1016/j.biopsych.2005.02.006 – volume: 5 start-page: F9 year: 2002 ident: pone.0252245.ref019 article-title: A neural basis for the development of inhibitory control publication-title: Developmental Science doi: 10.1111/1467-7687.00235 – start-page: 520 year: 2017 ident: pone.0252245.ref054 article-title: Harnessing the Neuroscience Revolution to Enhance Child and Adolescent Psychotherapy. In: Evidence Based Psychotherapies for Children and Adolescents publication-title: Guilford Press – volume: 10 start-page: 276 year: 1984 ident: pone.0252245.ref031 article-title: On the Ability to Inhibit Simple and Choice Reaction Time Responses: A Model and a Method publication-title: Journal of Experimental Psychology: Human Perception and Performance – volume: 37 start-page: 206 year: 2015 ident: pone.0252245.ref005 article-title: The New ABCs: A Practitioner’s Guide to Neuroscience-Informed Cognitive-Behavior Therapy publication-title: Journal of Mental Health Counseling doi: 10.17744/1040-2861-37.3.206 – volume: 75 start-page: 1357 year: 2004 ident: pone.0252245.ref013 article-title: Maturation of Cognitive Processes From Late Childhood to Adulthood publication-title: Child Development doi: 10.1111/j.1467-8624.2004.00745.x – volume: 1 year: 2018 ident: pone.0252245.ref051 article-title: Brain Mechanisms of Attention Orienting Following Frustration: Associations With Irritability and Age in Youths publication-title: American Journal of Psychiatry – volume: 382 start-page: 878 year: 2020 ident: pone.0252245.ref001 article-title: Medicine and the Mind publication-title: New England Journal of Medicine doi: 10.1056/NEJMc1916446 – volume: 53 start-page: 1109 year: 2012 ident: pone.0252245.ref067 article-title: The Affective Reactivity Index: a concise irritability scale for clinical and research settings: The Affective Reactivity Index publication-title: Journal of Child Psychology and Psychiatry doi: 10.1111/j.1469-7610.2012.02561.x – volume: 60 start-page: 991 year: 2006 ident: pone.0252245.ref043 article-title: Prevalence, Clinical Correlates, and Longitudinal Course of Severe Mood Dysregulation in Children publication-title: Biological Psychiatry doi: 10.1016/j.biopsych.2006.08.042 – volume: 45 start-page: 1 year: 2016 ident: pone.0252245.ref057 article-title: Technology: Bridging the Gap from Research to Practice publication-title: Cognitive Behaviour Therapy doi: 10.1080/16506073.2016.1143201 – volume: 3 start-page: 470 year: 2018 ident: pone.0252245.ref073 article-title: The psycho Package: an Efficient and Publishing-Oriented Workflow for Psychological Science publication-title: The Journal of Open Source Software doi: 10.21105/joss.00470 – volume: 21 start-page: 277 year: 2017 ident: pone.0252245.ref041 article-title: Pediatric Irritability: A Systems Neuroscience Approach publication-title: Trends in Cognitive Sciences doi: 10.1016/j.tics.2017.02.002 – volume: 38 start-page: 151 year: 2015 ident: pone.0252245.ref020 article-title: An Integrative Model of the Maturation of Cognitive Control publication-title: Annual Review of Neuroscience doi: 10.1146/annurev-neuro-071714-034054 – volume: 43 start-page: 302 year: 2006 ident: pone.0252245.ref023 article-title: The antisaccade task as a research tool in psychopathology: A critical review publication-title: Psychophysiology doi: 10.1111/j.1469-8986.2006.00403.x – volume: 2 start-page: 101 year: 1995 ident: pone.0252245.ref030 article-title: The flankers task and response competition: A useful tool for investigating a variety of cognitive problems publication-title: Visual Cognition doi: 10.1080/13506289508401726 – volume: 18 start-page: 1279 year: 1978 ident: pone.0252245.ref028 article-title: Primary and secondary saccades to goals defined by instructions publication-title: Vision Research doi: 10.1016/0042-6989(78)90218-3 – volume: 57 start-page: 1285 year: 2005 ident: pone.0252245.ref026 article-title: The Cognitive Neuroscience of Response Inhibition: Relevance for Genetic Research in Attention-Deficit/Hyperactivity Disorder publication-title: Biological Psychiatry doi: 10.1016/j.biopsych.2004.10.026 – volume: 86 start-page: 186 year: 2017 ident: pone.0252245.ref015 article-title: Unity and diversity of executive functions: Individual differences as a window on cognitive structure publication-title: Cortex doi: 10.1016/j.cortex.2016.04.023 – volume: 48 start-page: 631 year: 2007 ident: pone.0252245.ref042 article-title: Research Review: A neuroscience framework for pediatric anxiety disorders publication-title: Journal of Child Psychology and Psychiatry doi: 10.1111/j.1469-7610.2007.01751.x – volume: 117 start-page: 34 year: 1988 ident: pone.0252245.ref071 article-title: Pragmatics of Measuring Recognition Memory: Applications to Dementia and Amnesia publication-title: Journal of Experimental Psychology: General doi: 10.1037/0096-3445.117.1.34 – year: 2020 ident: pone.0252245.ref066 article-title: Computational Modeling of Attentional Impairments in Disruptive Mood Dysregulation and Attention Deficit/Hyperactivity Disorder publication-title: Journal of the American Academy of Child & Adolescent Psychiatry – start-page: 678 year: 2011 ident: pone.0252245.ref069 article-title: Conners comprehensive behavior rating scale. publication-title: Encyclopedia of clinical neuropsychology doi: 10.1007/978-0-387-79948-3_1536 – volume: 4 year: 2012 ident: pone.0252245.ref002 article-title: Revolution Stalled publication-title: Science Translational Medicine doi: 10.1126/scitranslmed.3003142 – volume: 4 start-page: 1 year: 2008 ident: pone.0252245.ref012 article-title: Ecological Momentary Assessment publication-title: Annual Review of Clinical Psychology doi: 10.1146/annurev.clinpsy.3.022806.091415 – volume: 1251 start-page: E1 year: 2012 ident: pone.0252245.ref036 article-title: Functional imaging studies of emotion regulation: a synthetic review and evolving model of the cognitive control of emotion: Functional imaging studies of emotion regulation publication-title: Annals of the New York Academy of Sciences doi: 10.1111/j.1749-6632.2012.06751.x – year: 2019 ident: pone.0252245.ref039 article-title: A Double-Blind Randomized Placebo-Controlled Trial of Citalopram Adjunctive to Stimulant Medication in Youth With Chronic Severe Irritability publication-title: Journal of the American Academy of Child & Adolescent Psychiatry – volume: 9 start-page: e13834 year: 2020 ident: pone.0252245.ref056 article-title: Digital Game Interventions for Youth Mental Health Services (Gaming My Way to Recovery): Protocol for a Scoping Review publication-title: JMIR Research Protocols doi: 10.2196/13834 – volume: 126 start-page: 220 year: 2000 ident: pone.0252245.ref010 article-title: On inhibition/disinhibition in developmental psychopathology: Views from cognitive and personality psychology and a working inhibition taxonomy publication-title: Psychological Bulletin doi: 10.1037/0033-2909.126.2.220 – volume: 30 start-page: 412 year: 1969 ident: pone.0252245.ref029 article-title: On the speed of mental processes publication-title: Acta Psychologica. doi: 10.1016/0001-6918(69)90065-1 – volume: 14 start-page: 151 year: 2015 ident: pone.0252245.ref003 article-title: The NIMH experimental medicine initiative publication-title: World Psychiatry doi: 10.1002/wps.20227 – start-page: 555 volume-title: Evidence-based psychotherapies for children and adolescents year: 2018 ident: pone.0252245.ref055 – volume: 74 start-page: 95 year: 2017 ident: pone.0252245.ref062 article-title: Association of Irritability and Anxiety With the Neural Mechanisms of Implicit Face Emotion Processing in Youths With Psychopathology publication-title: JAMA Psychiatry doi: 10.1001/jamapsychiatry.2016.3282 – volume: 108 start-page: 44 year: 2013 ident: pone.0252245.ref065 article-title: Inhibition and impulsivity: Behavioral and neural basis of response control publication-title: Progress in Neurobiology doi: 10.1016/j.pneurobio.2013.06.005 – volume: 15 start-page: 155 year: 2016 ident: pone.0252245.ref074 article-title: A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research publication-title: Journal of Chiropractic Medicine doi: 10.1016/j.jcm.2016.02.012 – volume: 36 start-page: 980 year: 1997 ident: pone.0252245.ref063 article-title: Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL): Initial Reliability and Validity Data publication-title: Journal of the American Academy of Child & Adolescent Psychiatry doi: 10.1097/00004583-199707000-00021 – volume: 34 start-page: 571 year: 1977 ident: pone.0252245.ref032 article-title: Sustained Attention in Children at Risk for Schizophrenia: Report on a Continuous Performance Test publication-title: Archives of General Psychiatry doi: 10.1001/archpsyc.1977.01770170081007 – volume: 7 start-page: 336 year: 2007 ident: pone.0252245.ref048 article-title: Anxiety and cognitive performance: Attentional control theory. publication-title: Emotion doi: 10.1037/1528-3542.7.2.336 – volume: 87 start-page: 345 year: 2014 ident: pone.0252245.ref035 article-title: Neural network of cognitive emotion regulation—An ALE meta-analysis and MACM analysis publication-title: NeuroImage doi: 10.1016/j.neuroimage.2013.11.001 – volume: 216 start-page: 109 year: 2017 ident: pone.0252245.ref060 article-title: Empirically derived patterns of psychiatric symptoms in youth: A latent profile analysis publication-title: Journal of Affective Disorders doi: 10.1016/j.jad.2016.09.016 – volume: 199 start-page: 439 year: 2008 ident: pone.0252245.ref017 article-title: The neuropsychopharmacology of action inhibition: cross-species translation of the stop-signal and go/no-go tasks publication-title: Psychopharmacology doi: 10.1007/s00213-008-1127-6 – volume: 31 start-page: 799 year: 2019 ident: pone.0252245.ref034 article-title: Emotion dysregulation and emerging psychopathology: A transdiagnostic, transdisciplinary perspective publication-title: Development and Psychopathology doi: 10.1017/S0954579419000671 |
| SSID | ssj0053866 |
| Score | 2.3773274 |
| Snippet | Identification of behavioral mechanisms underlying psychopathology is essential for the development of novel targeted therapeutics. However, this work relies... |
| SourceID | doaj pubmedcentral proquest gale crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Enrichment Source Index Database |
| StartPage | e0252245 |
| SubjectTerms | Behavioral assessment Biology and Life Sciences Equipment and supplies Health aspects Inhibition (Neurophysiology) Measurement Medicine and Health Sciences Methods Mobile applications Physical Sciences Psychological research Registered Report Protocol Social Sciences |
| Title | Rationale and validation of a novel mobile application probing motor inhibition: Proof of concept of CALM-IT |
| URI | https://www.proquest.com/docview/2537633704 https://pubmed.ncbi.nlm.nih.gov/PMC8177631 https://doaj.org/article/b8d7dd4a3f2b4ae1ade06f9129b6f1fe |
| Volume | 16 |
| WOSCitedRecordID | wos000664640100041&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: DOA dateStart: 20060101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M~E dateStart: 20060101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Advanced Technologies & Aerospace Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: P5Z dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/hightechjournals providerName: ProQuest – providerCode: PRVPQU databaseName: Agriculture Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M0K dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/agriculturejournals providerName: ProQuest – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M7P dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Engineering Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: M7S dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com providerName: ProQuest – providerCode: PRVPQU databaseName: Environmental Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: PATMY dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/environmentalscience providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 7X7 dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: Materials Science Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: KB. dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/materialsscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Nursing & Allied Health Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 7RV dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: BENPR dateStart: 20061201 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Publicly Available Content Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: PIMPY dateStart: 20061201 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVPQU databaseName: Public Health Database customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: 8C1 dateStart: 20061201 isFulltext: true titleUrlDefault: https://search.proquest.com/publichealth providerName: ProQuest – providerCode: PRVATS databaseName: Public Library of Science (PLoS) Journals Open Access customDbUrl: eissn: 1932-6203 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0053866 issn: 1932-6203 databaseCode: FPL dateStart: 20060101 isFulltext: true titleUrlDefault: http://www.plos.org/publications/ providerName: Public Library of Science |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3db9MwELdg8MALYnyIwigGIQEP6fJpJ7y11SqqtSXqRlV4iWzHZpFKMq3t_n7uErcs8DAeeDlF9Vlq7sN3js-_I-SdlDriiR85JhbaCZVkTuJ7ynFDGSQ6YNqrizEXEz6bxctlkt5o9YU1YQ08cCO4YxnnPM9DERhfhkJ7ItcuMwmEKcmMZzSuvpD17DZTzRoMXsyYvSgXcO_Y6qV3WZW6B1Ee4lbUCkQ1Xv_fq_KflZI3Qs_oEXloc0bab_7rIbmjy8fk0Hrlmn6w0NEfn5DV3H7b01SUOQUrKpqeSbQyVNCyutYr-rOSBTL8Prqm2FYGYhgMwRacFuVFIetSrk80hcza4GzV3G_Ex2F_MnXG50_J19HJ-fCzY_spOArylI2T5yB_L4hiJZgMIbMwTJmAS_Br3wgtIxZDTMuVcYWAxDvHwIXYMsb4geRcBc_IQQkSfE4ohL7clTr0XeRKoiTUrsFDbAYroDa8Q4KdcDNlwcax58Uqq0_QOGw6GtllqJLMqqRDnP2sywZs4xb-Aeptz4tQ2fUPYECZNaDsNgPqkNeo9ay5d7p3-KzPGLxlFDK3Q97WHAiXUWI9zg-xXa-z8ZfFPzCdzVtM7y2TqUAcStg7EPBOCMPV4jxqcYLTq9bwm52NZjiElXKlrrbrzEd8niDgbtghvGW8LTG1R8riokYWjz0Ok70X_0OuL8kDH-t_8ItVeEQONldb_YrcV9ebYn3VJXf5fIF0yWsaA42HXpfcG5zM0nm3dmego3QC9HTQAzp1T5HytKZnQNPoO8xIx9P02y_3M1Z6 |
| linkProvider | Directory of Open Access Journals |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Rationale+and+validation+of+a+novel+mobile+application+probing+motor+inhibition%3A+Proof+of+concept+of+CALM-IT&rft.jtitle=PloS+one&rft.au=Cardinale%2C+Elise+M.&rft.au=Naim%2C+Reut&rft.au=Haller%2C+Simone+P.&rft.au=German%2C+Ramaris&rft.date=2021-06-04&rft.pub=Public+Library+of+Science&rft.eissn=1932-6203&rft.volume=16&rft.issue=6&rft_id=info:doi/10.1371%2Fjournal.pone.0252245&rft_id=info%3Apmid%2F34086728&rft.externalDocID=PMC8177631 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1932-6203&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1932-6203&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1932-6203&client=summon |