Ferroptosis in Parkinson’s disease: glia–neuron crosstalk

Parkinson’s disease (PD) is characterized by dopaminergic (DA) neuron loss and the formation of cytoplasmic protein inclusions. Although the exact pathogenesis of PD is unknown, iron dyshomeostasis has been proposed as a potential contributing factor. Emerging evidence suggests that glial cell activ...

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Bibliographic Details
Published in:	Trends in molecular medicine Vol. 28; no. 4; pp. 258 - 269
Main Authors:	Wang, Zhang-Li, Yuan, Lin, Li, Wen, Li, Jia-Yi
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.04.2022
Subjects:	alpha-Synuclein - metabolism Basic Medicine Cell Death - physiology Dopaminergic Neurons - metabolism Ferroptosis glia Humans iron Medical and Health Sciences Medicin och hälsovetenskap Medicinska och farmaceutiska grundvetenskaper Neuroglia - metabolism neuron Neurosciences Neurovetenskaper Parkinson Disease - metabolism Parkinson's disease neuron iron Parkinson's disease ferroptosis glia
ISSN:	1471-4914, 1471-499X, 1471-499X
Online Access:	Get full text
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