Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report

Background Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell lung cancer. Case presentation This case repor...

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Vydáno v:Journal of medical case reports Ročník 17; číslo 1; s. 1 - 4
Hlavní autoři: Pușcașu, Alexandra-Ioana, Moinard-Butot, Fabien, Antoni, Delphine, Schott, Roland, Somme, Laura
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BioMed Central 18.09.2023
BioMed Central Ltd
Springer Nature B.V
BMC
Témata:
Acrometastasis
Adenocarcinoma
Bone marrow
Cancer
Case Report
Case reports
Chemotherapy
Family Medicine
General Practice
Genetic aspects
Immunotherapy
Internal Medicine
Literature reviews
Lung cancer
Lung cancer, Non-small cell
Magnetic resonance imaging
Medical prognosis
Medicine
Medicine & Public Health
Metabolism
Metastasis
Oligometastatic lung adenocarcinoma
Pemetrexed
Phalanx metastasis
Primary Care Medicine
Public Health
Rheumatism
Rheumatoid arthritis
Sarcoma
Surgical Oncology
Tomography
Tumors
Oligometastatic lung adenocarcinoma
Acrometastasis
Phalanx metastasis
ISSN:1752-1947, 1752-1947
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Shrnutí:Background Acrometastasis is an uncommon finding in non-small cell lung cancer and is usually a sign of multimetastatic disease. Few case reports have suggested solitary digital metastasis as the single secondary lesion of oligometastatic non-small cell lung cancer. Case presentation This case report describes an unusual presentation of a Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma with a solitary bone metastasis in the fourth finger medial phalanx, which was also the first sign of the disease, in a 63-year-old Caucasian female patient. Digital surgical amputation was performed. After histopathological confirmation and radiological exclusion of other secondary lesions, chemoimmunotherapy in a first-line setting was initiated. A partial metabolic response in the primary lung lesion was observed after four cycles. Maintenance therapy is currently being continued. Conclusion Solitary digital metastasis is a rare finding in non-small cell lung cancer. Further studies are needed to investigate the mechanisms behind this particular dissemination process.
Bibliografie:ObjectType-Case Study-2
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ISSN:1752-1947
1752-1947
DOI:10.1186/s13256-023-04127-1