Interpretation of the evidence for the efficacy and safety of statin therapy

This Review is intended to help clinicians, patients, and the public make informed decisions about statin therapy for the prevention of heart attacks and strokes. It explains how the evidence that is available from randomised controlled trials yields reliable information about both the efficacy and...

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Bibliographic Details
Published in:	The Lancet (British edition) Vol. 388; no. 10059; pp. 2532 - 2561
Main Authors:	Collins, Rory, Reith, Christina, Emberson, Jonathan, Armitage, Jane, Baigent, Colin, Blackwell, Lisa, Blumenthal, Roger, Danesh, John, Smith, George Davey, DeMets, David, Evans, Stephen, Law, Malcolm, MacMahon, Stephen, Martin, Seth, Neal, Bruce, Poulter, Neil, Preiss, David, Ridker, Paul, Roberts, Ian, Rodgers, Anthony, Sandercock, Peter, Schulz, Kenneth, Sever, Peter, Simes, John, Smeeth, Liam, Wald, Nicholas, Yusuf, Salim, Peto, Richard
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 19.11.2016 Elsevier Limited
Subjects:	Anticholesteremic Agents - therapeutic use Cardiovascular disease Cholesterol Cholesterol, LDL - blood Clinical outcomes Clinical Trials as Topic Coronary Disease - drug therapy Coronary Disease - prevention & control Drug therapy Drug-Related Side Effects and Adverse Reactions Health risks Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Internal Medicine Myocardial Infarction - drug therapy Myocardial Infarction - prevention & control Pain Patient safety Patients Prevention Risk Assessment Safety Side effects Simvastatin - therapeutic use Statins Stroke - drug therapy Stroke - prevention & control Studies Vascular diseases
ISSN:	0140-6736, 1474-547X
Online Access:	Get full text
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