A single chemotherapy administration induces muscle atrophy, mitochondrial alterations and apoptosis in breast cancer patients

Background Breast cancer patients are commonly treated with sequential administrations of epirubicin–cyclophosphamide (EC) and paclitaxel (TAX). The chronic effect of this treatment induces skeletal muscle alterations, but the specific effect of each chemotherapy agent is unknown. This study aimed t...

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Veröffentlicht in:	Journal of cachexia, sarcopenia and muscle Jg. 15; H. 1; S. 292 - 305
Hauptverfasser:	Mallard, Joris, Hucteau, Elyse, Bender, Laura, Moinard‐Butot, Fabien, Rochelle, Emma, Boutonnet, Lauréline, Grandperrin, Antoine, Schott, Roland, Pflumio, Carole, Trensz, Philippe, Kalish‐Weindling, Michal, Charles, Anne‐Laure, Gény, Bernard, Favret, Fabrice, Pivot, Xavier, Hureau, Thomas J., Pagano, Allan F.
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Germany John Wiley & Sons, Inc 01.02.2024 Wiley Open Access/Springer Verlag Wiley
Schlagworte:	Anthracycline‐cyclophosphamide Apoptosis Biopsy Breast cancer Cancer Cancer therapies Cell cycle Chemotherapy Homeostasis Life Sciences Mitochondria Mitochondrial respiration Muscle biopsies Musculoskeletal system Reactive oxygen species Respiration Skeletal muscle deconditioning Taxanes Mitochondrial respiration Mitochondria Muscle biopsies Anthracycline-cyclophosphamide Skeletal muscle deconditioning Taxanes metabolism pathology
ISSN:	2190-5991, 2190-6009, 2190-6009
Online-Zugang:	Volltext
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