Nanozymes-recent development and biomedical applications

Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes. In the field of biomedicine, nanozymes are capturing tremendous attention due to their high stability and low cost. Enzyme-mimetic activities of nanozymes can be reg...

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Vydáno v:Journal of nanobiotechnology Ročník 20; číslo 1; s. 92 - 18
Hlavní autoři: Ren, Xiangyi, Chen, Dongxu, Wang, Yan, Li, Huifang, Zhang, Yabing, Chen, Hongying, Li, Xi, Huo, Minfeng
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BioMed Central 22.02.2022
BioMed Central Ltd
BMC
Témata:
Biomedical engineering
Biotechnology
Catalysis
Chemistry
Chemistry and Materials Science
Disease therapy
Health aspects
Hydrogen Peroxide
Methods
Molecular Medicine
Nanostructures - chemistry
Nanotechnology
Nanozyme
Oxidative stress
Peroxides
Properties
Reactive oxygen species
Review
China
Oxidative stress
Nanozyme
Disease therapy
Reactive oxygen species
ISSN:1477-3155, 1477-3155
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Popis
Shrnutí:Nanozyme is a series of nanomaterials with enzyme-mimetic activities that can proceed with the catalytic reactions of natural enzymes. In the field of biomedicine, nanozymes are capturing tremendous attention due to their high stability and low cost. Enzyme-mimetic activities of nanozymes can be regulated by multiple factors, such as the chemical state of metal ion, pH, hydrogen peroxide (H 2 O 2 ), and glutathione (GSH) level, presenting great promise for biomedical applications. Over the past decade, multi-functional nanozymes have been developed for various biomedical applications. To promote the understandings of nanozymes and the development of novel and multifunctional nanozymes, we herein provide a comprehensive review of the nanozymes and their applications in the biomedical field. Nanozymes with versatile enzyme-like properties are briefly overviewed, and their mechanism and application are discussed to provide understandings for future research. Finally, underlying challenges and prospects of nanozymes in the biomedical frontier are discussed in this review. Graphical Abstract
Bibliografie:ObjectType-Article-1
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ISSN:1477-3155
1477-3155
DOI:10.1186/s12951-022-01295-y