Insect-specific virus evolution and potential effects on vector competence

The advancement in high-throughput sequencing technology and bioinformatics tools has spurred a new age of viral discovery. Arthropods is the largest group of animals and has shown to be a major reservoir of different viruses, including a group known as insect-specific viruses (ISVs). The majority o...

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Veröffentlicht in:	Virus genes Jg. 55; H. 2; S. 127 - 137
Hauptverfasser:	Öhlund, Pontus, Lundén, Hanna, Blomström, Anne-Lie
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Springer US 01.04.2019 Springer Nature B.V
Schlagworte:	Animals arboviruses Arboviruses - genetics Arboviruses - pathogenicity arthropods Bioinformatics Biological control biological control agents Biomedical and Life Sciences Biomedicine Culicidae Culicidae - genetics Culicidae - virology evolution Flaviviridae Flaviviridae - genetics Flaviviridae - pathogenicity High-Throughput Nucleotide Sequencing Insect Vectors - virology Insect Viruses - genetics Insect Viruses - pathogenicity Medical Microbiology Microbiology Microbiology in the medical area Mikrobiologi Mikrobiologi inom det medicinska området Next-generation sequencing Pathobiology pathogens Patobiologi Pest Control, Biological Phenuiviridae Plant Sciences Public health Species Specificity Togaviridae Togaviridae - genetics Togaviridae - pathogenicity Tropism vector competence vectorial capacity vertebrates Virology Virus Diseases - genetics Virus Diseases - virology Virus Replication - genetics Viruses Wolbachia Evolution Arbovirus Vector competence Insect-specific virus
ISSN:	0920-8569, 1572-994X, 1572-994X
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The advancement in high-throughput sequencing technology and bioinformatics tools has spurred a new age of viral discovery. Arthropods is the largest group of animals and has shown to be a major reservoir of different viruses, including a group known as insect-specific viruses (ISVs). The majority of known ISVs have been isolated from mosquitoes and shown to belong to viral families associated with animal arbovirus pathogens, such as Flaviviridae, Togaviridae and Phenuiviridae . These insect-specific viruses have a strict tropism and are unable to replicate in vertebrate cells, these properties are interesting for many reasons. One is that these viruses could potentially be utilised as biocontrol agents using a similar strategy as for Wolbachia . Mosquitoes infected with the viral agent could have inferior vectorial capacity of arboviruses resulting in a decrease of circulating arboviruses of public health importance. Moreover, insect-specific viruses are thought to be ancestral to arboviruses and could be used to study the evolution of the switch from single-host to dual-host. In this review, we discuss new discoveries and hypothesis in the field of arboviruses and insect-specific viruses.
Bibliographie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Literature Review-3 ObjectType-Review-3 content type line 23 Edited by A. Lorena Passarelli.
ISSN:	0920-8569 1572-994X 1572-994X
DOI:	10.1007/s11262-018-01629-9