A 3D convolutional neural network to classify subjects as Alzheimer's disease, frontotemporal dementia or healthy controls using brain 18F-FDG PET

•Visual interpretation of [18F]-FDG-PET scans remains challenging and with the advent of new treatments, accurate diagnosis is more important than ever.•A tailor-made 3D VGG16-like network outperforms clinical interpretation by specialist physicians, achieving an overall accuracy of 89.8 % in predic...

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