JS-MS: a cross-platform, modular javascript viewer for mass spectrometry signals

Background Despite the ubiquity of mass spectrometry (MS), data processing tools can be surprisingly limited. To date, there is no stand-alone, cross-platform 3-D visualizer for MS data. Available visualization toolkits require large libraries with multiple dependencies and are not well suited for c...

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Vydáno v:BMC bioinformatics Ročník 18; číslo 1; s. 469 - 7
Hlavní autoři: Rosen, Jebediah, Handy, Kyle, Gillan, André, Smith, Rob
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BioMed Central 06.11.2017
BioMed Central Ltd
BMC
Témata:
3-D visualization
Algorithms
Analysis
Bioinformatics
Biomedical and Life Sciences
Computational Biology/Bioinformatics
Computer Appl. in Life Sciences
Electronic Data Processing
Internet
JavaScript (Programming language)
JavaScript mass spectrometry parsing
Life Sciences
Mass Spectrometry
Mass spectrometry data processing
Mass spectrometry JavaScript
Mass spectrometry visualization
Microarrays
Proteomics
Software
User-Computer Interface
JavaScript mass spectrometry parsing
Mass spectrometry visualization
3-D visualization
Mass spectrometry JavaScript
Mass spectrometry data processing
ISSN:1471-2105, 1471-2105
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Shrnutí:Background Despite the ubiquity of mass spectrometry (MS), data processing tools can be surprisingly limited. To date, there is no stand-alone, cross-platform 3-D visualizer for MS data. Available visualization toolkits require large libraries with multiple dependencies and are not well suited for custom MS data processing modules, such as MS storage systems or data processing algorithms. Results We present JS-MS, a 3-D, modular JavaScript client application for viewing MS data. JS-MS provides several advantages over existing MS viewers, such as a dependency-free, browser-based, one click, cross-platform install and better navigation interfaces. The client includes a modular Java backend with a novel streaming.mzML parser to demonstrate the API-based serving of MS data to the viewer. Conclusions JS-MS enables custom MS data processing and evaluation by providing fast, 3-D visualization using improved navigation without dependencies. JS-MS is publicly available with a GPLv2 license at github.com/optimusmoose/jsms.
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ISSN:1471-2105
1471-2105
DOI:10.1186/s12859-017-1883-6