Novel ssRNA phage VLP platform for displaying foreign epitopes by genetic fusion

Virus-like particles (VLPs) can be used as efficient carriers of various antigens and therefore serve as attractive tools in vaccine development. Although VLPs of different viruses can be used, VLPs of ssRNA phages have convincing advantages due to their unique properties, including efficient protei...

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Bibliographic Details
Published in:	Vaccine Vol. 38; no. 38; pp. 6019 - 6026
Main Authors:	Liekniņa, Ilva, Černova, Darja, Rūmnieks, Jānis, Tārs, Kaspars
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 27.08.2020 Elsevier Limited Elsevier
Subjects:	Allergy and Immunology Antibodies Antigens Bacteriophages Coat protein coat proteins Coating Disease Epitopes Epitopes - genetics Genetic engineering Genomes Humans Influenza Influenza Vaccines Influenza, Human Leviviridae Mutation peptides Phages Plasmids Production costs protein synthesis Proteins ssRNA bacteriophages Vaccine development Vaccines Vaccines, Virus-Like Particle - genetics Virus-like particles Viruses VLP vaccines Yeast yeasts ssRNA bacteriophages Virus-like particles VLP vaccines
ISSN:	0264-410X, 1873-2518, 1873-2518
Online Access:	Get full text
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