Physical activity, cardiovascular health, quality of life and blood pressure control in hypertensive subjects: randomized clinical trial

Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardio...

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Vydáno v:	Health and quality of life outcomes Ročník 16; číslo 1; s. 184 - 11
Hlavní autoři:	Arija, Victoria, Villalobos, Felipe, Pedret, Roser, Vinuesa, Angels, Jovani, Dolors, Pascual, Gabriel, Basora, Josep
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 14.09.2018 BioMed Central Ltd BMC
Témata:	Adult Aged Analysis Blood Pressure Care and treatment Clinical trials Exercise Therapy Female Health aspects Health Status Health Status Indicators Humans Hypertension - physiopathology Hypertension - psychology Hypertension - therapy Male Medicine Medicine & Public Health Middle Aged Physical fitness Primary Health Care Quality of Life Quality of Life Research Risk factors Treatment Outcome Type 2 diabetes Walking Socio-cultural Activities Physical Component Summary Walking Group Hypertensive Subjects Health-related Quality Of Life (HRQoL)
ISSN:	1477-7525, 1477-7525
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Abstract	Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects. Methods A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied. Results In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (− 1.19 points) and the systolic BP (− 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline. Conclusions This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension. Trial registration Clinicaltrials.gov ID NCT02767739 ; Trial registered on May 5th, 2016. Retrospectively registered.
AbstractList	Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects. Methods A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied. Results In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (- 1.19 points) and the systolic BP (- 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline. Conclusions This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension. Trial registration Clinicaltrials.gov ID NCT02767739; Trial registered on May 5th, 2016. Retrospectively registered. Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects. A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied. In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (- 1.19 points) and the systolic BP (- 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline. This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension. Abstract Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects. Methods A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied. Results In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (− 1.19 points) and the systolic BP (− 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline. Conclusions This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension. Trial registration Clinicaltrials.gov ID NCT02767739; Trial registered on May 5th, 2016. Retrospectively registered. Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects.BACKGROUNDPhysical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects.A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied.METHODSA randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied.In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (- 1.19 points) and the systolic BP (- 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline.RESULTSIn multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (- 1.19 points) and the systolic BP (- 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline.This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension.CONCLUSIONSThis PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension.Clinicaltrials.gov ID NCT02767739 ; Trial registered on May 5th, 2016. Retrospectively registered.TRIAL REGISTRATIONClinicaltrials.gov ID NCT02767739 ; Trial registered on May 5th, 2016. Retrospectively registered. Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects. A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied. In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (- 1.19 points) and the systolic BP (- 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline. This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension. Clinicaltrials.gov ID NCT02767739 ; Trial registered on May 5th, 2016. Retrospectively registered. Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control has rarely been studied in hypertensive subjects. Our aim was to evaluate the effectiveness of a PA intervention programme on cardiovascular disease (CVD) risk, HRQoL and BP control in hypertensive subjects. Methods A randomized clinical trial, with a PA intervention programme of 9 months duration, comprising a walking group of 120 min/week, supervised, and with socio-cultural activities. Participants were 207 hypertensive subjects (68.2 years, 76.8% women). PA (IPAQ-s), diet, CVD risk, BP, BMI, smoking, and HRQoL (SF-36) were assessed at baseline and at the end of the intervention. Changes in CVD risk and in HRQoL during the intervention was calculated (end-baseline score). Multivariate models were applied. Results In multivariate models, the PA intervention programme, with no modification of the diet, decreased CVD risk (− 1.19 points) and the systolic BP (− 8.68 mmHg), and increased some areas of HRQoL (4.45 to 14.62 points). An increase in the percentage of subjects with controlled BP was observed by the PA programme itself (OR 5.395 to 5.785 according to multivariate models), and by the changes during the intervention in the decrease in CVD risk (OR 0.609) and in the increase in the HRQoL in physical component summary (OR 1.041), role physical (OR 1.010), and bodily pain (OR 1.014), independently of controlled BP at baseline. Conclusions This PA intervention programme improved cardiovascular health and HRQoL, and favoured BP control in primary care users with hypertension. Trial registration Clinicaltrials.gov ID NCT02767739 ; Trial registered on May 5th, 2016. Retrospectively registered.
ArticleNumber	184
Audience	Academic
Author	Basora, Josep Pedret, Roser Arija, Victoria Jovani, Dolors Vinuesa, Angels Villalobos, Felipe Pascual, Gabriel
Author_xml	– sequence: 1 givenname: Victoria surname: Arija fullname: Arija, Victoria email: victoria.arija@urv.cat organization: Unitat Suport a la Recerca Reus-Tarragona, Institut d’Investigació en Atenció Primária, IDIAP Jordi Gol (Barcelona), Institut d’Investigació Sanitària Pere Virgili, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili – sequence: 2 givenname: Felipe surname: Villalobos fullname: Villalobos, Felipe organization: Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili – sequence: 3 givenname: Roser surname: Pedret fullname: Pedret, Roser organization: Primary Health Care Area, Institut Català de la Salut, Generalitat de Catalunya – sequence: 4 givenname: Angels surname: Vinuesa fullname: Vinuesa, Angels organization: Primary Health Care Area, Institut Català de la Salut, Generalitat de Catalunya – sequence: 5 givenname: Dolors surname: Jovani fullname: Jovani, Dolors organization: Primary Health Care Area, Institut Català de la Salut, Generalitat de Catalunya – sequence: 6 givenname: Gabriel surname: Pascual fullname: Pascual, Gabriel organization: Primary Health Care Area, Institut Català de la Salut, Generalitat de Catalunya – sequence: 7 givenname: Josep surname: Basora fullname: Basora, Josep organization: Unitat Suport a la Recerca Reus-Tarragona, Institut d’Investigació en Atenció Primária, IDIAP Jordi Gol (Barcelona), Institut d’Investigació Sanitària Pere Virgili, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Primary Health Care Area, Institut Català de la Salut, Generalitat de Catalunya
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/30217193$$D View this record in MEDLINE/PubMed
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Keywords	Socio-cultural Activities Physical Component Summary Walking Group Hypertensive Subjects Health-related Quality Of Life (HRQoL)
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PublicationTitle	Health and quality of life outcomes
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PublicationYear	2018
Publisher	BioMed Central BioMed Central Ltd BMC
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Snippet	Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP)... Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP) control... Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood pressure (BP)... Abstract Background Physical activity (PA) promotes cardiovascular health and health related quality of life (HRQoL), although the effect of that on blood...
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SubjectTerms	Adult Aged Analysis Blood Pressure Care and treatment Clinical trials Exercise Therapy Female Health aspects Health Status Health Status Indicators Humans Hypertension - physiopathology Hypertension - psychology Hypertension - therapy Male Medicine Medicine & Public Health Middle Aged Physical fitness Primary Health Care Quality of Life Quality of Life Research Risk factors Treatment Outcome Type 2 diabetes Walking
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Title	Physical activity, cardiovascular health, quality of life and blood pressure control in hypertensive subjects: randomized clinical trial
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