Gold nanoparticles affect the antioxidant status in selected normal human cells

This study evaluates the cytotoxicity of AuNPs coated with polyallylamine (AuNPs-PAA) and conjugated or not to the epidermal growth factor receptor (EGFR)-targeting antibody Cetuximab (AuNPs-PAA-Ctxb) in normal human kidney (HK-2), liver (THLE-2) and microvascular endothelial (TIME) cells, and compa...

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Veröffentlicht in:	International journal of nanomedicine Jg. 14; S. 4991 - 5015
Hauptverfasser:	Daems, Noami, Penninckx, Sébastien, Nelissen, Inge, Van Hoecke, Karen, Cardinaels, Thomas, Baatout, Sarah, Michiels, Carine, Lucas, Stéphane, Aerts, An
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New Zealand Dove Medical Press Limited 01.07.2019 Taylor & Francis Ltd Dove Dove Medical Press
Schlagworte:	Antibodies Antioxidants (Nutrients) Apoptosis Cancer Cell growth Cells (Biology) Cetuximab Cysteine Cystine Cytotoxicity EDTA EGFR Endothelium Epidermal growth factors Gold Immunotherapy Kidneys Kinases Liver Monoclonal antibodies Nanomaterials Nanoparticles Nuclear physics Nuclear research Original Research Oxidative stress Proteins Targeted cancer therapy Thioredoxins United Kingdom Netherlands Belgium France Germany United Kingdom > UK Cetuximab EGFR cytotoxicity oxidative stress
ISSN:	1178-2013, 1176-9114, 1178-2013
Online-Zugang:	Volltext
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