Choroid plexus volume in multiple sclerosis can be estimated on structural MRI avoiding contrast injection
We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery...
Uložené v:
| Vydané v: | European radiology experimental Ročník 8; číslo 1; s. 33 - 10 |
|---|---|
| Hlavní autori: | , , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
| Vydavateľské údaje: |
Vienna
Springer Vienna
27.02.2024
Springer Nature B.V SpringerOpen |
| Predmet: | |
| ISSN: | 2509-9280, 2509-9280 |
| On-line prístup: | Získať plný text |
| Tagy: |
Pridať tag
Žiadne tagy, Buďte prvý, kto otaguje tento záznam!
|
| Abstract | We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23.77 and 18.49, T1w 13.73 and 7.44, FLAIR 13.09 and 10.77, respectively). Manual segmentation of ChP resulted 3.073 ± 0.563 mL (mean ± standard deviation) on T1w, 3.787 ± 0.679 mL on FLAIR, and 2.984 ± 0.506 mL on CE-T1w images, with an error of 28.02 ± 19.02% for FLAIR and 3.52 ± 12.61% for T1w. FLAIR overestimated ChP volume compared to CE-T1w (
p
< 0.001). The Dice similarity coefficient of CE-T1w
versus
T1w and FLAIR was 0.67 ± 0.05 and 0.68 ± 0.05, respectively. Spatial error distribution per slice was calculated after nonlinear coregistration to the standard MNI152 space and showed a heterogeneous profile along the ChP especially near the fornix and the hippocampus. Quantitative analyses suggest T1w as a surrogate of CE-T1w to estimate ChP volume.
Relevance statement
To estimate the ChP volume, CE-T1w can be replaced by non-CE T1w sequences because the error is acceptable, while FLAIR overestimates the ChP volume. This encourages the development of automatic tools for ChP segmentation, also improving the understanding of the role of the ChP volume in multiple sclerosis, promoting longitudinal studies.
Key points
• CE-T1w sequences are considered the reference standard for ChP manual segmentation.
• FLAIR sequences showed a higher CNR than T1w sequences but overestimated the ChP volume.
• Non-CE T1w sequences can be a surrogate of CE-T1w sequences for manual segmentation of ChP.
Graphical Abstract |
|---|---|
| AbstractList | Abstract We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23.77 and 18.49, T1w 13.73 and 7.44, FLAIR 13.09 and 10.77, respectively). Manual segmentation of ChP resulted 3.073 ± 0.563 mL (mean ± standard deviation) on T1w, 3.787 ± 0.679 mL on FLAIR, and 2.984 ± 0.506 mL on CE-T1w images, with an error of 28.02 ± 19.02% for FLAIR and 3.52 ± 12.61% for T1w. FLAIR overestimated ChP volume compared to CE-T1w (p < 0.001). The Dice similarity coefficient of CE-T1w versus T1w and FLAIR was 0.67 ± 0.05 and 0.68 ± 0.05, respectively. Spatial error distribution per slice was calculated after nonlinear coregistration to the standard MNI152 space and showed a heterogeneous profile along the ChP especially near the fornix and the hippocampus. Quantitative analyses suggest T1w as a surrogate of CE-T1w to estimate ChP volume. Relevance statement To estimate the ChP volume, CE-T1w can be replaced by non-CE T1w sequences because the error is acceptable, while FLAIR overestimates the ChP volume. This encourages the development of automatic tools for ChP segmentation, also improving the understanding of the role of the ChP volume in multiple sclerosis, promoting longitudinal studies. Key points • CE-T1w sequences are considered the reference standard for ChP manual segmentation. • FLAIR sequences showed a higher CNR than T1w sequences but overestimated the ChP volume. • Non-CE T1w sequences can be a surrogate of CE-T1w sequences for manual segmentation of ChP. Graphical Abstract We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23.77 and 18.49, T1w 13.73 and 7.44, FLAIR 13.09 and 10.77, respectively). Manual segmentation of ChP resulted 3.073 ± 0.563 mL (mean ± standard deviation) on T1w, 3.787 ± 0.679 mL on FLAIR, and 2.984 ± 0.506 mL on CE-T1w images, with an error of 28.02 ± 19.02% for FLAIR and 3.52 ± 12.61% for T1w. FLAIR overestimated ChP volume compared to CE-T1w (p < 0.001). The Dice similarity coefficient of CE-T1w versus T1w and FLAIR was 0.67 ± 0.05 and 0.68 ± 0.05, respectively. Spatial error distribution per slice was calculated after nonlinear coregistration to the standard MNI152 space and showed a heterogeneous profile along the ChP especially near the fornix and the hippocampus. Quantitative analyses suggest T1w as a surrogate of CE-T1w to estimate ChP volume. Relevance statement To estimate the ChP volume, CE-T1w can be replaced by non-CE T1w sequences because the error is acceptable, while FLAIR overestimates the ChP volume. This encourages the development of automatic tools for ChP segmentation, also improving the understanding of the role of the ChP volume in multiple sclerosis, promoting longitudinal studies. Key points • CE-T1w sequences are considered the reference standard for ChP manual segmentation. • FLAIR sequences showed a higher CNR than T1w sequences but overestimated the ChP volume. • Non-CE T1w sequences can be a surrogate of CE-T1w sequences for manual segmentation of ChP. We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23.77 and 18.49, T1w 13.73 and 7.44, FLAIR 13.09 and 10.77, respectively). Manual segmentation of ChP resulted 3.073 ± 0.563 mL (mean ± standard deviation) on T1w, 3.787 ± 0.679 mL on FLAIR, and 2.984 ± 0.506 mL on CE-T1w images, with an error of 28.02 ± 19.02% for FLAIR and 3.52 ± 12.61% for T1w. FLAIR overestimated ChP volume compared to CE-T1w ( p < 0.001). The Dice similarity coefficient of CE-T1w versus T1w and FLAIR was 0.67 ± 0.05 and 0.68 ± 0.05, respectively. Spatial error distribution per slice was calculated after nonlinear coregistration to the standard MNI152 space and showed a heterogeneous profile along the ChP especially near the fornix and the hippocampus. Quantitative analyses suggest T1w as a surrogate of CE-T1w to estimate ChP volume. Relevance statement To estimate the ChP volume, CE-T1w can be replaced by non-CE T1w sequences because the error is acceptable, while FLAIR overestimates the ChP volume. This encourages the development of automatic tools for ChP segmentation, also improving the understanding of the role of the ChP volume in multiple sclerosis, promoting longitudinal studies. Key points • CE-T1w sequences are considered the reference standard for ChP manual segmentation. • FLAIR sequences showed a higher CNR than T1w sequences but overestimated the ChP volume. • Non-CE T1w sequences can be a surrogate of CE-T1w sequences for manual segmentation of ChP. Graphical Abstract We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23.77 and 18.49, T1w 13.73 and 7.44, FLAIR 13.09 and 10.77, respectively). Manual segmentation of ChP resulted 3.073 ± 0.563 mL (mean ± standard deviation) on T1w, 3.787 ± 0.679 mL on FLAIR, and 2.984 ± 0.506 mL on CE-T1w images, with an error of 28.02 ± 19.02% for FLAIR and 3.52 ± 12.61% for T1w. FLAIR overestimated ChP volume compared to CE-T1w (p < 0.001). The Dice similarity coefficient of CE-T1w versus T1w and FLAIR was 0.67 ± 0.05 and 0.68 ± 0.05, respectively. Spatial error distribution per slice was calculated after nonlinear coregistration to the standard MNI152 space and showed a heterogeneous profile along the ChP especially near the fornix and the hippocampus. Quantitative analyses suggest T1w as a surrogate of CE-T1w to estimate ChP volume.Relevance statement To estimate the ChP volume, CE-T1w can be replaced by non-CE T1w sequences because the error is acceptable, while FLAIR overestimates the ChP volume. This encourages the development of automatic tools for ChP segmentation, also improving the understanding of the role of the ChP volume in multiple sclerosis, promoting longitudinal studies.Key points • CE-T1w sequences are considered the reference standard for ChP manual segmentation.• FLAIR sequences showed a higher CNR than T1w sequences but overestimated the ChP volume.• Non-CE T1w sequences can be a surrogate of CE-T1w sequences for manual segmentation of ChP.We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61 multiple sclerosis patients prospectively included. ChP was separately segmented on T1w, T2-weighted (T2w) fluid-attenuated inversion-recovery (FLAIR), and CE-T1w sequences. Inter-rater variability assessed on 10 subjects showed high reproducibility between sequences measured by intraclass correlation coefficient (T1w 0.93, FLAIR 0.93, CE-T1w 0.99). CE-T1w showed higher signal-to-noise ratio and contrast-to-noise ratio (CE-T1w 23.77 and 18.49, T1w 13.73 and 7.44, FLAIR 13.09 and 10.77, respectively). Manual segmentation of ChP resulted 3.073 ± 0.563 mL (mean ± standard deviation) on T1w, 3.787 ± 0.679 mL on FLAIR, and 2.984 ± 0.506 mL on CE-T1w images, with an error of 28.02 ± 19.02% for FLAIR and 3.52 ± 12.61% for T1w. FLAIR overestimated ChP volume compared to CE-T1w (p < 0.001). The Dice similarity coefficient of CE-T1w versus T1w and FLAIR was 0.67 ± 0.05 and 0.68 ± 0.05, respectively. Spatial error distribution per slice was calculated after nonlinear coregistration to the standard MNI152 space and showed a heterogeneous profile along the ChP especially near the fornix and the hippocampus. Quantitative analyses suggest T1w as a surrogate of CE-T1w to estimate ChP volume.Relevance statement To estimate the ChP volume, CE-T1w can be replaced by non-CE T1w sequences because the error is acceptable, while FLAIR overestimates the ChP volume. This encourages the development of automatic tools for ChP segmentation, also improving the understanding of the role of the ChP volume in multiple sclerosis, promoting longitudinal studies.Key points • CE-T1w sequences are considered the reference standard for ChP manual segmentation.• FLAIR sequences showed a higher CNR than T1w sequences but overestimated the ChP volume.• Non-CE T1w sequences can be a surrogate of CE-T1w sequences for manual segmentation of ChP. |
| ArticleNumber | 33 |
| Author | Visani, Valentina Tamanti, Agnese Natale, Valerio Calabrese, Massimiliano Anglani, Mariagiulia Castellaro, Marco Pizzini, Francesca B. Bertoldo, Alessandra |
| Author_xml | – sequence: 1 givenname: Valentina orcidid: 0000-0002-3467-7920 surname: Visani fullname: Visani, Valentina organization: Department of Information Engineering, University of Padova – sequence: 2 givenname: Francesca B. orcidid: 0000-0002-6285-0989 surname: Pizzini fullname: Pizzini, Francesca B. organization: Department of Engineering for Innovation Medicine, University of Verona – sequence: 3 givenname: Valerio surname: Natale fullname: Natale, Valerio organization: Department of Diagnostic and Public Health, University of Verona – sequence: 4 givenname: Agnese orcidid: 0000-0001-9972-4348 surname: Tamanti fullname: Tamanti, Agnese organization: Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona – sequence: 5 givenname: Mariagiulia orcidid: 0000-0002-3989-4553 surname: Anglani fullname: Anglani, Mariagiulia organization: Neuroradiology Unit, University Hospital of Padova – sequence: 6 givenname: Alessandra orcidid: 0000-0002-6262-6354 surname: Bertoldo fullname: Bertoldo, Alessandra organization: Department of Information Engineering, University of Padova, Padova Neuroscience Center, University of Padova – sequence: 7 givenname: Massimiliano orcidid: 0000-0002-3362-7403 surname: Calabrese fullname: Calabrese, Massimiliano organization: Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona – sequence: 8 givenname: Marco orcidid: 0000-0002-1203-2670 surname: Castellaro fullname: Castellaro, Marco email: marco.castellaro@unipd.it organization: Department of Information Engineering, University of Padova |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38409562$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9kktvEzEUhUeoiJbSP8ACWWLDZsCv8dgrhCIekYqQEKwtv5I6mtjB9kTw77lpWmi76MpX9jmfzvW9z7uTlFPoupcEvyVEineVk5GPPaa8x5hT0qsn3RkdsOoVlfjkTn3aXdS6wRgTpdQg5LPulEmOoaRn3WZxlUuOHu2m8HuuaJ-neRtQTGg7Ty3CLapuCiXXWJEzCdmAQm1xa1rwKCdUW5ldm4uZ0NfvS2T2AItpjVxOrZjaALUJrsWcXnRPV2aq4eLmPO9-fvr4Y_Glv_z2ebn4cNk7gWXryWpkgo1kUHKwAloNkpEBC2YVFnakfLABc8_saO0YsAiOWOtXjgnjOaGUnXfLI9dns9G7AlnLH51N1NcXuay1KS1CV9oxZYgbvaLBca-8IdQHIdVohXGKC2C9P7J2s90G78Khqeke9P5Lild6nfeaYKAQyoDw5oZQ8q8Zvk5vY3VhmkwKea6aKkY5o4pgkL5-IN3kuST4q4OKSKkUG0D16m6kf1luZwoCeRQ4mFotYaVdbOYwAUgYJ4imDxukjxukYYP09QZpBVb6wHpLf9TEjqYK4rQO5X_sR1x_Afv-2SI |
| CitedBy_id | crossref_primary_10_1016_j_msard_2024_105668 crossref_primary_10_1177_13524585241292965 crossref_primary_10_1212_NXI_0000000000200319 crossref_primary_10_1016_j_jns_2025_123393 |
| Cites_doi | 10.1016/S1053-8119(09)70884-5 10.1016/j.neuroimage.2006.01.015 10.1073/pnas.2115221118 10.3390/ijms21218217 10.1016/j.mri.2018.12.010 10.1186/s12987-020-00218-z 10.1148/radiol.2021204426 10.3389/fnmol.2019.00034 10.1016/j.nicl.2023.103368 10.1016/S1474-4422(17)30158-8 10.1007/s11064-015-1581-6 10.2967/jnumed.118.223834 10.1016/j.jacr.2019.04.005 10.3233/JAD-190706 10.1093/schbul/sbz100 10.1148/radiol.2020200073 10.1016/j.neurobiolaging.2020.01.005 10.1002/hbm.26224 10.1016/j.jneuroim.2008.04.035 10.1016/S1474-4422(21)00095-8 10.1016/j.expneurol.2015.02.032 10.3389/fimmu.2018.03116 10.1016/j.nicl.2021.102926 10.1002/1097-0029(20010101)52:1<112::AID-JEMT13>3.0.CO;2-5 10.1073/pnas.2025000118 10.1016/j.neuroimage.2010.09.025 10.1152/physrev.00004.2013 10.4103/1673-5374.180372 10.1016/j.neuroimage.2012.01.021 10.1176/appi.ajp.2019.18070825 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2024 2024. The Author(s). The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: The Author(s) 2024 – notice: 2024. The Author(s). – notice: The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7RV 7XB 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU DWQXO FYUFA GHDGH KB0 NAPCQ PHGZM PHGZT PIMPY PKEHL PPXIY PQEST PQQKQ PQUKI 7X8 5PM DOA |
| DOI | 10.1186/s41747-024-00421-9 |
| DatabaseName | Springer Nature Open Access Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Nursing & Allied Health Database ProQuest Central (purchase pre-March 2016) ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) Nursing & Allied Health Database (Alumni Edition) Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest One Academic Eastern Edition ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Central Nursing & Allied Health Premium Health Research Premium Collection ProQuest One Academic UKI Edition ProQuest Central Korea ProQuest Nursing & Allied Health Source (Alumni) ProQuest Central (New) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | CrossRef MEDLINE - Academic Publicly Available Content Database MEDLINE |
| Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals (DOAJ) url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: 7RV name: Nursing & Allied Health Database url: https://search.proquest.com/nahs sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 2509-9280 |
| EndPage | 10 |
| ExternalDocumentID | oai_doaj_org_article_c39a1c7d92ec4d9da12de6897b6ac946 PMC10897123 38409562 10_1186_s41747_024_00421_9 |
| Genre | Journal Article |
| GroupedDBID | 0R~ 7RV 8FI 8FJ AAFWJ AAJSJ AAKKN ABEEZ ABUWG ACACY ACGFS ACULB ADBBV AFGXO AFKRA AFPKN ALIPV ALMA_UNASSIGNED_HOLDINGS AMKLP AOIJS BCNDV BENPR BKEYQ BPHCQ BVXVI C24 C6C CCPQU EBLON EBS EMOBN FYUFA GROUPED_DOAJ HYE IAO IHR ITC M~E NAPCQ OK1 PGMZT PIMPY PQQKQ PROAC RPM RSV SOJ UKHRP AASML AAYXX AFFHD CITATION PHGZM PHGZT PPXIY CGR CUY CVF ECM EIF NPM 3V. 7XB 8FK AZQEC DWQXO PKEHL PQEST PQUKI 7X8 5PM |
| ID | FETCH-LOGICAL-c608t-1f7363715985b6186e8315063b906b7245be04d3b7bb7e06ec1bbdfc36ad41223 |
| IEDL.DBID | DOA |
| ISICitedReferencesCount | 5 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=001171692600001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 2509-9280 |
| IngestDate | Thu Dec 04 16:44:55 EST 2025 Tue Nov 04 02:05:54 EST 2025 Sun Nov 09 13:42:10 EST 2025 Sat Oct 11 13:41:01 EDT 2025 Wed Feb 19 02:11:54 EST 2025 Tue Nov 18 21:41:37 EST 2025 Sat Nov 29 01:34:26 EST 2025 Fri Feb 21 02:40:25 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Choroid plexus Image segmentation Multiple sclerosis Magnetic resonance imaging Gadolinium-based contrast media |
| Language | English |
| License | 2024. The Author(s). Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c608t-1f7363715985b6186e8315063b906b7245be04d3b7bb7e06ec1bbdfc36ad41223 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| ORCID | 0000-0002-3467-7920 0000-0002-6262-6354 0000-0002-1203-2670 0000-0002-6285-0989 0000-0002-3989-4553 0000-0002-3362-7403 0000-0001-9972-4348 |
| OpenAccessLink | https://doaj.org/article/c39a1c7d92ec4d9da12de6897b6ac946 |
| PMID | 38409562 |
| PQID | 2931889935 |
| PQPubID | 4402887 |
| PageCount | 10 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_c39a1c7d92ec4d9da12de6897b6ac946 pubmedcentral_primary_oai_pubmedcentral_nih_gov_10897123 proquest_miscellaneous_2932432910 proquest_journals_2931889935 pubmed_primary_38409562 crossref_citationtrail_10_1186_s41747_024_00421_9 crossref_primary_10_1186_s41747_024_00421_9 springer_journals_10_1186_s41747_024_00421_9 |
| PublicationCentury | 2000 |
| PublicationDate | 2024-02-27 |
| PublicationDateYYYYMMDD | 2024-02-27 |
| PublicationDate_xml | – month: 02 year: 2024 text: 2024-02-27 day: 27 |
| PublicationDecade | 2020 |
| PublicationPlace | Vienna |
| PublicationPlace_xml | – name: Vienna – name: England – name: London |
| PublicationTitle | European radiology experimental |
| PublicationTitleAbbrev | Eur Radiol Exp |
| PublicationTitleAlternate | Eur Radiol Exp |
| PublicationYear | 2024 |
| Publisher | Springer Vienna Springer Nature B.V SpringerOpen |
| Publisher_xml | – name: Springer Vienna – name: Springer Nature B.V – name: SpringerOpen |
| References | Jessen, Munk, Lundgaard, Nedergaard (CR4) 2015; 40 Monaco, Nicholas, Reynolds, Magliozzi (CR5) 2020; 21 Tadayon, Moret, Sprugnoli (CR10) 2020; 74 Zhao, Taso, Dai, Press, Alsop (CR16) 2020; 17 Maekawa, Hori, Murata (CR15) 2019; 57 Balusu, Brkic, Libert, Vandenbroucke (CR2) 2016; 11 Lizano, Lutz, Ling (CR13) 2019; 176 Manouchehri, Stüve (CR19) 2021; 118 Avants, Tustison, Song, Cook, Klein, Gee (CR26) 2011; 54 Lassmann (CR9) 2018; 9 Fonov, Evans, McKinstry, Almli, Collins (CR27) 2009; 47 Rudie, Mattay, Schindler (CR30) 2019; 16 Senay, Seethaler, Makris (CR23) 2023; 44 Althubaity, Schubert, Martins (CR12) 2022; 33 Schubert, Veronese, Marchitelli (CR17) 2019; 60 Wattjes, Ciccarelli, Reich (CR22) 2021; 20 Hubert, Chauveau, Dumot (CR20) 2019; 12 Gulani, Calamante, Shellock, Kanal, Reeder (CR28) 2017; 16 Engelhardt, Wolburg-Buchholz, Wolburg (CR6) 2001; 52 Tadayon, Pascual-Leone, Press, Santarnecchi (CR11) 2020; 89 Damkier, Brown, Praetorius (CR1) 2013; 93 Schieda, van der Pol, Walker (CR29) 2020; 297 Spector, Keep, Robert Snodgrass, Smith, Johanson (CR3) 2015; 267 Yushkevich, Piven, Hazlett (CR24) 2006; 31 Ricigliano, Morena, Colombi (CR7) 2021; 301 Fleischer, Gonzalez-Escamilla, Ciolac (CR18) 2021; 118 Vercellino, Votta, Condello (CR8) 2008; 199 Zhou, Huang, Zhang (CR14) 2020; 46 Fischl (CR25) 2012; 62 Yazdan-Panah, Schmidt-Mengin, Ricigliano (CR21) 2023; 38 HH Damkier (421_CR1) 2013; 93 P Lizano (421_CR13) 2019; 176 PA Yushkevich (421_CR24) 2006; 31 S Balusu (421_CR2) 2016; 11 MP Wattjes (421_CR22) 2021; 20 VAG Ricigliano (421_CR7) 2021; 301 N Althubaity (421_CR12) 2022; 33 YF Zhou (421_CR14) 2020; 46 M Vercellino (421_CR8) 2008; 199 R Spector (421_CR3) 2015; 267 BB Avants (421_CR26) 2011; 54 NA Jessen (421_CR4) 2015; 40 N Schieda (421_CR29) 2020; 297 V Hubert (421_CR20) 2019; 12 N Manouchehri (421_CR19) 2021; 118 E Tadayon (421_CR11) 2020; 89 JD Rudie (421_CR30) 2019; 16 JJ Schubert (421_CR17) 2019; 60 A Yazdan-Panah (421_CR21) 2023; 38 E Tadayon (421_CR10) 2020; 74 B Fischl (421_CR25) 2012; 62 T Maekawa (421_CR15) 2019; 57 V Fleischer (421_CR18) 2021; 118 B Engelhardt (421_CR6) 2001; 52 O Senay (421_CR23) 2023; 44 H Lassmann (421_CR9) 2018; 9 S Monaco (421_CR5) 2020; 21 V Gulani (421_CR28) 2017; 16 V Fonov (421_CR27) 2009; 47 L Zhao (421_CR16) 2020; 17 |
| References_xml | – volume: 47 start-page: S102 year: 2009 ident: CR27 article-title: Unbiased nonlinear average age-appropriate brain templates from birth to adulthood publication-title: Neuroimage doi: 10.1016/S1053-8119(09)70884-5 – volume: 31 start-page: 1116 year: 2006 end-page: 1128 ident: CR24 article-title: User-guided 3D active contour segmentation of anatomical structures: significantly improved efficiency and reliability publication-title: Neuroimage doi: 10.1016/j.neuroimage.2006.01.015 – volume: 118 start-page: e2115221118 year: 2021 ident: CR19 article-title: Choroid plexus volumetrics and brain inflammation in multiple sclerosis publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.2115221118 – volume: 21 start-page: 8217 year: 2020 ident: CR5 article-title: Intrathecal inflammation in progressive multiple sclerosis publication-title: Int J Mol Sci doi: 10.3390/ijms21218217 – volume: 57 start-page: 323 year: 2019 end-page: 327 ident: CR15 article-title: Choroid plexus cysts analyzed using diffusion-weighted imaging with short diffusion-time publication-title: Magn Reson Imaging doi: 10.1016/j.mri.2018.12.010 – volume: 17 start-page: 58 year: 2020 ident: CR16 article-title: Non-invasive measurement of choroid plexus apparent blood flow with arterial spin labeling publication-title: Fluids Barriers CNS doi: 10.1186/s12987-020-00218-z – volume: 301 start-page: 166 year: 2021 end-page: 177 ident: CR7 article-title: Choroid plexus enlargement in inflammatory multiple sclerosis: 3.0-T MRI and translocator protein PET evaluation publication-title: Radiology doi: 10.1148/radiol.2021204426 – volume: 12 start-page: 34 year: 2019 ident: CR20 article-title: Clinical imaging of choroid plexus in health and in brain disorders: a mini-review publication-title: Front Mol Neurosci doi: 10.3389/fnmol.2019.00034 – volume: 38 start-page: 103368 year: 2023 ident: CR21 article-title: Automatic segmentation of the choroid plexuses: Method and validation in controls and patients with multiple sclerosis publication-title: Neuroimage Clin doi: 10.1016/j.nicl.2023.103368 – volume: 16 start-page: 564 year: 2017 end-page: 570 ident: CR28 article-title: Gadolinium deposition in the brain: summary of evidence and recommendations publication-title: Lancet Neurol doi: 10.1016/S1474-4422(17)30158-8 – volume: 40 start-page: 2583 year: 2015 end-page: 2599 ident: CR4 article-title: The glymphatic system: a beginner’s guide publication-title: Neurochem Res doi: 10.1007/s11064-015-1581-6 – volume: 60 start-page: 1452 year: 2019 end-page: 1460 ident: CR17 article-title: Dynamic 11C-PiB PET shows cerebrospinal fluid flow alterations in Alzheimer disease and multiple sclerosis publication-title: J Nucl Med doi: 10.2967/jnumed.118.223834 – volume: 16 start-page: 1158 year: 2019 end-page: 1164 ident: CR30 article-title: An initiative to reduce unnecessary gadolinium-based contrast in multiple sclerosis patients publication-title: J Am Coll Radiol doi: 10.1016/j.jacr.2019.04.005 – volume: 74 start-page: 1057 year: 2020 end-page: 1068 ident: CR10 article-title: Improving choroid plexus segmentation in the healthy and diseased brain: relevance for tau-PET imaging in dementia publication-title: J Alzheimers Dis doi: 10.3233/JAD-190706 – volume: 46 start-page: 722 year: 2020 end-page: 731 ident: CR14 article-title: Choroid plexus enlargement and allostatic load in schizophrenia publication-title: Schizophr Bull doi: 10.1093/schbul/sbz100 – volume: 297 start-page: 565 year: 2020 end-page: 572 ident: CR29 article-title: Adverse events to the gadolinium-based contrast agent gadoxetic acid: systematic review and meta-analysis publication-title: Radiology doi: 10.1148/radiol.2020200073 – volume: 89 start-page: 108 year: 2020 end-page: 117 ident: CR11 article-title: Choroid plexus volume is associated with levels of CSF proteins: relevance for Alzheimer’s and Parkinson’s disease publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2020.01.005 – volume: 44 start-page: 2465 year: 2023 end-page: 2478 ident: CR23 article-title: A preliminary choroid plexus volumetric study in individuals with psychosis publication-title: Hum Brain Mapp doi: 10.1002/hbm.26224 – volume: 199 start-page: 133 year: 2008 end-page: 141 ident: CR8 article-title: Involvement of the choroid plexus in multiple sclerosis autoimmune inflammation: a neuropathological study publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2008.04.035 – volume: 20 start-page: 653 year: 2021 end-page: 670 ident: CR22 article-title: 2021 MAGNIMS–CMSC–NAIMS consensus recommendations on the use of MRI in patients with multiple sclerosis publication-title: Lancet Neurol doi: 10.1016/S1474-4422(21)00095-8 – volume: 267 start-page: 78 year: 2015 end-page: 86 ident: CR3 article-title: A balanced view of choroid plexus structure and function: focus on adult humans publication-title: Exp Neurol doi: 10.1016/j.expneurol.2015.02.032 – volume: 9 start-page: 3116 year: 2018 ident: CR9 article-title: Pathogenic mechanisms associated with different clinical courses of multiple sclerosis publication-title: Front Immunol doi: 10.3389/fimmu.2018.03116 – volume: 33 start-page: 102926 year: 2022 ident: CR12 article-title: Choroid plexus enlargement is associated with neuroinflammation and reduction of blood brain barrier permeability in depression publication-title: NeuroImage Clin doi: 10.1016/j.nicl.2021.102926 – volume: 52 start-page: 112 year: 2001 end-page: 129 ident: CR6 article-title: Involvement of the choroid plexus in central nervous system inflammation publication-title: Microsc Res Tech doi: 10.1002/1097-0029(20010101)52:1<112::AID-JEMT13>3.0.CO;2-5 – volume: 118 start-page: e2025000118 year: 2021 ident: CR18 article-title: Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.2025000118 – volume: 54 start-page: 2033 year: 2011 end-page: 2044 ident: CR26 article-title: A reproducible evaluation of ANTs similarity metric performance in brain image registration publication-title: Neuroimage doi: 10.1016/j.neuroimage.2010.09.025 – volume: 93 start-page: 1847 year: 2013 end-page: 1892 ident: CR1 article-title: Cerebrospinal fluid secretion by the choroid plexus publication-title: Physiol Rev doi: 10.1152/physrev.00004.2013 – volume: 11 start-page: 534 year: 2016 end-page: 537 ident: CR2 article-title: The choroid plexus-cerebrospinal fluid interface in Alzheimer’s disease: more than just a barrier publication-title: Neural Regen Res doi: 10.4103/1673-5374.180372 – volume: 62 start-page: 774 year: 2012 end-page: 781 ident: CR25 publication-title: FreeSurfer. NeuroImage doi: 10.1016/j.neuroimage.2012.01.021 – volume: 176 start-page: 564 year: 2019 end-page: 572 ident: CR13 article-title: Association of choroid plexus enlargement with cognitive, inflammatory, and structural phenotypes across the psychosis spectrum publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.2019.18070825 – volume: 9 start-page: 3116 year: 2018 ident: 421_CR9 publication-title: Front Immunol doi: 10.3389/fimmu.2018.03116 – volume: 11 start-page: 534 year: 2016 ident: 421_CR2 publication-title: Neural Regen Res doi: 10.4103/1673-5374.180372 – volume: 16 start-page: 564 year: 2017 ident: 421_CR28 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(17)30158-8 – volume: 46 start-page: 722 year: 2020 ident: 421_CR14 publication-title: Schizophr Bull doi: 10.1093/schbul/sbz100 – volume: 118 start-page: e2115221118 year: 2021 ident: 421_CR19 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.2115221118 – volume: 20 start-page: 653 year: 2021 ident: 421_CR22 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(21)00095-8 – volume: 199 start-page: 133 year: 2008 ident: 421_CR8 publication-title: J Neuroimmunol doi: 10.1016/j.jneuroim.2008.04.035 – volume: 31 start-page: 1116 year: 2006 ident: 421_CR24 publication-title: Neuroimage doi: 10.1016/j.neuroimage.2006.01.015 – volume: 60 start-page: 1452 year: 2019 ident: 421_CR17 publication-title: J Nucl Med doi: 10.2967/jnumed.118.223834 – volume: 44 start-page: 2465 year: 2023 ident: 421_CR23 publication-title: Hum Brain Mapp doi: 10.1002/hbm.26224 – volume: 267 start-page: 78 year: 2015 ident: 421_CR3 publication-title: Exp Neurol doi: 10.1016/j.expneurol.2015.02.032 – volume: 297 start-page: 565 year: 2020 ident: 421_CR29 publication-title: Radiology doi: 10.1148/radiol.2020200073 – volume: 17 start-page: 58 year: 2020 ident: 421_CR16 publication-title: Fluids Barriers CNS doi: 10.1186/s12987-020-00218-z – volume: 74 start-page: 1057 year: 2020 ident: 421_CR10 publication-title: J Alzheimers Dis doi: 10.3233/JAD-190706 – volume: 93 start-page: 1847 year: 2013 ident: 421_CR1 publication-title: Physiol Rev doi: 10.1152/physrev.00004.2013 – volume: 40 start-page: 2583 year: 2015 ident: 421_CR4 publication-title: Neurochem Res doi: 10.1007/s11064-015-1581-6 – volume: 12 start-page: 34 year: 2019 ident: 421_CR20 publication-title: Front Mol Neurosci doi: 10.3389/fnmol.2019.00034 – volume: 301 start-page: 166 year: 2021 ident: 421_CR7 publication-title: Radiology doi: 10.1148/radiol.2021204426 – volume: 47 start-page: S102 year: 2009 ident: 421_CR27 publication-title: Neuroimage doi: 10.1016/S1053-8119(09)70884-5 – volume: 33 start-page: 102926 year: 2022 ident: 421_CR12 publication-title: NeuroImage Clin doi: 10.1016/j.nicl.2021.102926 – volume: 62 start-page: 774 year: 2012 ident: 421_CR25 publication-title: FreeSurfer. NeuroImage doi: 10.1016/j.neuroimage.2012.01.021 – volume: 16 start-page: 1158 year: 2019 ident: 421_CR30 publication-title: J Am Coll Radiol doi: 10.1016/j.jacr.2019.04.005 – volume: 52 start-page: 112 year: 2001 ident: 421_CR6 publication-title: Microsc Res Tech doi: 10.1002/1097-0029(20010101)52:1<112::AID-JEMT13>3.0.CO;2-5 – volume: 21 start-page: 8217 year: 2020 ident: 421_CR5 publication-title: Int J Mol Sci doi: 10.3390/ijms21218217 – volume: 57 start-page: 323 year: 2019 ident: 421_CR15 publication-title: Magn Reson Imaging doi: 10.1016/j.mri.2018.12.010 – volume: 176 start-page: 564 year: 2019 ident: 421_CR13 publication-title: Am J Psychiatry doi: 10.1176/appi.ajp.2019.18070825 – volume: 89 start-page: 108 year: 2020 ident: 421_CR11 publication-title: Neurobiol Aging doi: 10.1016/j.neurobiolaging.2020.01.005 – volume: 54 start-page: 2033 year: 2011 ident: 421_CR26 publication-title: Neuroimage doi: 10.1016/j.neuroimage.2010.09.025 – volume: 118 start-page: e2025000118 year: 2021 ident: 421_CR18 publication-title: Proc Natl Acad Sci U S A doi: 10.1073/pnas.2025000118 – volume: 38 start-page: 103368 year: 2023 ident: 421_CR21 publication-title: Neuroimage Clin doi: 10.1016/j.nicl.2023.103368 |
| SSID | ssj0001999568 |
| Score | 2.2888901 |
| Snippet | We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w) sequences in 61... Abstract We compared choroid plexus (ChP) manual segmentation on non-contrast-enhanced (non-CE) sequences and reference standard CE T1- weighted (T1w)... |
| SourceID | doaj pubmedcentral proquest pubmed crossref springer |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 33 |
| SubjectTerms | Choroid plexus Choroid Plexus - diagnostic imaging Diagnostic Radiology Gadolinium-based contrast media Humans Image segmentation Imaging Internal Medicine Interventional Radiology Magnetic Resonance Imaging Medicine Medicine & Public Health Multiple sclerosis Multiple Sclerosis - diagnostic imaging Neuroradiology Radiology Reproducibility of Results Signal-To-Noise Ratio Technical Note Ultrasound |
| SummonAdditionalLinks | – databaseName: ProQuest Central dbid: BENPR link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Jb9QwFH6CKUJc2JdAQUbiBlHHsePlhGjVCg4dVRVIvUXehqaqkmEyrfj5PDvJjIalF66Jbdl-iz_bz98DeMeMCgEdXx7QknLu5gFNqvQ5L6T0Mpi5Uy4lm5CzmTo70yfDgVs3hFWOPjE5at-6eEa-h8sSVbg5YOXHxY88Zo2Kt6tDCo3bsBOZyvgEdvYPZyenm1MWHV9uqvG1jBJ7HUcMLnNcmvKosDTXWytSIu7_G9r8M2jyt5vTtCAdPfjfoTyE-wMUJZ963XkEt0LzGO4eD5ftT-Di4LxdtrUni8vw86ojvSMjdUPGKETSYUUcVN0RlBCxgUTODsTAwZO2IT03beT1IMenX4i5xsZwKCSFx5tuhU1dpEiw5il8Ozr8evA5H1Iz5E5M1Sqnc8kEk4iFVGkj5X5QLHIVMqunwsqClzZMuWdWWivDVARHrfVzx4TxnCIkeQaTpm3CCyAslAYnw6LnFZzOlWKW60hL40snDS0zoKN4Kjfwlsf0GZdV2r8oUfUirVCkVRJppTN4v66z6Fk7biy9H6W-LhkZt9OHdvm9Ggy4ckwb6qTXRXDca29o4YNQWlphnOYig91R2NXgBrpqI-kM3q5_owHHWxnThPYqlSk4KxC2ZfC8V7F1T1jcfiNCzUBtKd9WV7f_NPV5IgmnU-wbwpIMPox6uunXv-fi5c3DeAX3imQ68U3XLkxQj8JruOOuV3W3fDNY3y_razfP priority: 102 providerName: ProQuest – databaseName: SpringerLINK dbid: C24 link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB5BQYgL70egICNxg4g4dvw4wooKDq0QAqk3y6_Qraqk2myr_vyOnWTRQkGCa2JHY_sb-3M88xngNbMqRpz4yoieVHLfRnSpJpS8ljLIaFuvfL5sQh4cqMND_WVKChvmaPf5SDLP1NmtlXg3cCTPssQ1pUxIo6W-DjcaqnTC9WLKcch_VnTK1lRzhsyVVbdWoSzWfxXD_D1Q8pfT0rwI7d39P_PvwZ2JdJL3I0ruw7XYPYBb-9Ox-kM4Xhz1q34ZyOlJvDgbyDhlkWVH5nhDMmBFbMpyIDgWxEWS1DmQ7cZA-o6MKrRJwYPsf_1M7Dl-DI0jORDeDmv81HGO-eoewfe9j98Wn8rpEobSi0qtS9pKJphE1qMal8T1o2JJlZA5XQkna964WPHAnHROxkpET50LrWfCBk6RfDyGna7v4lMgLDYWt3cO51jBaasUc1wnAZrQeGlpUwCdB8X4SaE8XZRxYvJORQkzdqLBTjS5E40u4M2mzumoz_HX0h_SWG9KJm3t_KBf_TCTqxrPtKVeBl1Hz4MOltYhCqWlE9ZrLgrYnZFiJocfDLImqrBxDFvxavMaXTWdv9gu9me5TM1ZjQStgCcjsDaWsLTRRi5agNqC3Jap22-65VGWA6cV2oYEpIC3M_J-2vXnvnj2b8Wfw-06gzdlc-3CDuIqvoCb_ny9HFYvswdeAnkBK8s priority: 102 providerName: Springer Nature |
| Title | Choroid plexus volume in multiple sclerosis can be estimated on structural MRI avoiding contrast injection |
| URI | https://link.springer.com/article/10.1186/s41747-024-00421-9 https://www.ncbi.nlm.nih.gov/pubmed/38409562 https://www.proquest.com/docview/2931889935 https://www.proquest.com/docview/2932432910 https://pubmed.ncbi.nlm.nih.gov/PMC10897123 https://doaj.org/article/c39a1c7d92ec4d9da12de6897b6ac946 |
| Volume | 8 |
| WOSCitedRecordID | wos001171692600001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVAON databaseName: Directory of Open Access Journals (DOAJ) customDbUrl: eissn: 2509-9280 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001999568 issn: 2509-9280 databaseCode: DOA dateStart: 20170101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 2509-9280 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001999568 issn: 2509-9280 databaseCode: M~E dateStart: 20170101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Nursing & Allied Health Database customDbUrl: eissn: 2509-9280 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001999568 issn: 2509-9280 databaseCode: 7RV dateStart: 20190201 isFulltext: true titleUrlDefault: https://search.proquest.com/nahs providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 2509-9280 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001999568 issn: 2509-9280 databaseCode: BENPR dateStart: 20190201 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 2509-9280 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001999568 issn: 2509-9280 databaseCode: PIMPY dateStart: 20190201 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVAVX databaseName: SpringerOpen customDbUrl: eissn: 2509-9280 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0001999568 issn: 2509-9280 databaseCode: C24 dateStart: 20171201 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Jb9QwFLagIMQFsZZAGRmJG0SNY8fLkY6moocZjUaAhlPkLWqqKqmaacWJ386zkwwd1guXSImd6Pkt9uf4-TNCb6iW3kPHl3qIpJTZykNIFS5luRBOeF1ZaeNhE2KxkOu1Wt446ivkhPX0wL3iDi1VmljhVO4tc8ppkjvPpRKGa6tYJNsG1HNjMhX_rqiwY1OOu2QkP-wYYG-RwpCUBkclqdoZiSJh_-9Q5q_Jkj-tmMaB6PghejAgSPy-l_wRuuWbx-jefFgjf4LOpqftZVs7fHHuv151uO9_cN3gMXkQd_AiyFR3GBSLjceBagOgq3e4bXBPKRvoOPB8dYL1NXwMJMExq113G_jUWUzgap6iT8ezj9MP6XCiQmp5JjcpqQTlVACEkYUJTPle0kAxSI3KuBE5K4zPmKNGGCN8xr0lxrjKUq4dI4AknqG9pm38c4SpLzTM1Qx0mJyRSkpqmApsMq6wQpMiQWTUbmkHuvFw6sV5Gacdkpe9RUqwSBktUqoEvd2-c9GTbfy19lEw2rZmIMqOD8B9ysF9yn-5T4IORpOXQ_R2JUAgIqFxFFrxelsMcRcWU3Tj26tYJ2c0B7SVoP3eQ7aS0DBrBmCZILnjOzui7pY09Wnk9iYZyAZoIkHvRjf7IdefdfHif-jiJbqfx_gIG7YO0B54m3-F7trrTd1dTtBtsfocrms5QXeOZovlCu6mOZvE0IPr_NsMSpYn8-WX7yl8MF8 |
| linkProvider | Directory of Open Access Journals |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Jb9QwFLaqgoAL-xIoYCQ4QdQ4TrwcEIJC1VE7I1QV1JvrbehUVTI00wJ_it_Is5PMaFh664Fr4lj2y_cW28_fQ-g51cJ7MHypB01KCzv2oFKlS4ucc8e9HlthY7EJPhqJ_X35cQX97O_ChLTK3iZGQ-1qG_bI18EtEQGLA1q-mX5NQ9WocLral9BoYbHtf3yDJVvzevAe_u-LPN_8sLexlXZVBVLLMjFLyZhTRjm4cVGawBbvBQ00e9TIjBmeF6XxWeGo4cZwnzFviTFubCnTriB5IDoAk38J7DgJKWR89_NiT0eGe6Kiv5sj2HpTQMTPU3CEaVAPksol_xfLBPwttv0zRfO3c9ro_jZv_G-Cu4mud4E2fttqxi204qvb6MqwSyW4g442DuuTeuLw9Nh_P21wa6bxpMJ9jiVu4EMQ4qTBgD9sPA6MJBDhe4frCrfMu4G1BA93B1ifQWcgOhyT_3Uzg66OYp5bdRd9upCZ3kOrVV35BwhTX2oQvgG_wgoyFoKaQgbSHVdarkmZINLDQdmOlT0UBzlWcXUmmGohpABCKkJIyQS9nH8zbTlJzm39LqBs3jLwiccH9ckX1ZknZanUxHInc28LJ50mufNMSG6YtrJgCVrrwaU6I9eoBbIS9Gz-GsxTOHPSla9PY5u8oKArWYLut5Cej4SGzQWIvxMklsC-NNTlN9XkMFKgkwzGBkFXgl71erEY179l8fD8aTxFV7f2hjtqZzDafoSu5VFtw-21NbQKmPKP0WV7Nps0J0-i3mN0cNH68guyapFw |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELagoIpLeUOggJG4QdQ4dvw4wsKKCrqqEEi9WX6l3apKVptt1Z_P2EkWFgoS4ho_NLZn7M-Zmc8IvaJGhgAbXx7AknLm6gAmVfmclUJ4EUztpEuPTYjZTB4dqcOfsvhTtPvokuxzGiJLU7PaW_i6N3HJ9zoGQFrkcL7kUetIrq6jG9EjFa9fkyHfIf1lUTFzU47ZMlc23TiREnH_VWjz96DJXzyn6UCa3v7_odxBOwMYxW977bmLroXmHto-GNzt99Hp5KRdtnOPF2fh8rzD_VaG5w0e4xBxBw1hWPMOwxphG3Bk7QAUHDxuG9yz00ZmD3zwZR-bC-gMBMUpQN50K-jqNMWCNQ_Qt-mHr5OP-fA4Q-54IVc5qQXlVAAakpWNpPtB0shWSK0quBUlq2womKdWWCtCwYMj1vraUW48IwBKHqKtpm3CY4RpqAxc-yzsvZyRWkpqmYrENL5ywpAqQ2RcIO0G5vL4gMaZTjcYyXU_iRomUadJ1CpDr9dtFj1vx19rv4vrvq4ZObfTh3Z5rAcT1o4qQ5zwqgyOeeUNKX3gUgnLjVOMZ2h31Bo9bASdBjRFJAyOwiherovBhKNfxjShPU91SkZLAG4ZetQr2VoSGi_ggFEzJDfUb0PUzZJmfpJowkkBsgEwydCbUQt_yPXnuXjyb9VfoO3D91P9eX_26Sm6VSY9jglfu2gLVCw8QzfdxWreLZ8nw_wOCFs3lA |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Choroid+plexus+volume+in+multiple+sclerosis+can+be+estimated+on+structural+MRI+avoiding+contrast+injection&rft.jtitle=European+radiology+experimental&rft.au=Visani%2C+Valentina&rft.au=Pizzini%2C+Francesca+B.&rft.au=Natale%2C+Valerio&rft.au=Tamanti%2C+Agnese&rft.date=2024-02-27&rft.pub=Springer+Vienna&rft.eissn=2509-9280&rft.volume=8&rft_id=info:doi/10.1186%2Fs41747-024-00421-9&rft.externalDocID=PMC10897123 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2509-9280&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2509-9280&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2509-9280&client=summon |