Safety, effectiveness, and adherence of a short and all-oral treatment regimen for the treatment of rifampicin-resistant tuberculosis in Niger: a study protocol of a pragmatic randomised clinical trial with stratified block randomisation

Background Rifampicin-resistant tuberculosis (RR-TB) treatment requires combination treatment, which frequently causes serious adverse events and globally results in not much more than 60% treatment success. In Niger, a high cure rate was obtained with a RR-TB treatment strategy based on a second-li...

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Vydané v:	Current controlled trials in cardiovascular medicine Ročník 23; číslo 1; s. 1011 - 14
Hlavní autori:	Souleymane, Mahamadou Bassirou, Decroo, Tom, Soumana, Alphazazi, Maman Lawan, Ibrahim, Gagara-Issoufou, Assiatou, Halidou-Moussa, Souleymane, Ortuño-Gutiérrez, Nimer, Adehossi, Eric, Mamadou, Saïdou, Van Deun, Armand, Piubello, Alberto
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	London BioMed Central 13.12.2022 BioMed Central Ltd Springer Nature B.V BMC
Predmet:	All oral treatment Antitubercular agents Antitubercular Agents - adverse effects Audiometry Biomedicine Care and treatment Clinical trials Contraindications Corporate sponsorship Diagnosis Dosage and administration Drugs Evaluation Health Sciences Hearing loss Humans Informed consent Laboratories Linezolid - adverse effects Medicine Medicine & Public Health New anti-tuberculosis drugs Niger Patient compliance Patient outcomes Patients Randomized Controlled Trials as Topic Rifampicin resistance tuberculosis Rifampin - adverse effects Statistics for Life Sciences Study Protocol Success Testing Tuberculosis Tuberculosis, Multidrug-Resistant - diagnosis Tuberculosis, Multidrug-Resistant - drug therapy Tuberculosis, Pulmonary - diagnosis Niger New anti-tuberculosis drugs All oral treatment Niger Rifampicin resistance tuberculosis
ISSN:	1745-6215, 1745-6215
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