Immunomodulatory agents for COVID-19 treatment: possible mechanism of action and immunopathology features

The novel coronavirus pandemic has emerged as one of the significant medical-health challenges of the current century. The World Health Organization has named this new virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the first detection of SARS-CoV-2 in November 2019 in Wuha...

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Bibliographic Details
Published in:	Molecular and cellular biochemistry Vol. 477; no. 3; pp. 711 - 726
Main Authors:	Rommasi, Foad, Nasiri, Mohammad Javad, Mirsaeidi, Mehdi
Format:	Journal Article
Language:	English
Published:	New York Springer US 01.03.2022 Springer Springer Nature B.V
Subjects:	ACE2 Alveoli Analysis Angiotensin Angiotensin-converting enzyme 2 Anosmia Antagonists Antibodies, Monoclonal, Humanized - immunology Antibodies, Monoclonal, Humanized - pharmacology Antiviral Agents - immunology Antiviral Agents - pharmacology Azetidines - immunology Azetidines - pharmacology Biochemistry Biological products Biomedical and Life Sciences Blood vessels Cardiology Care and treatment Chemical compounds Clinical trials Coronaviruses Cough COVID-19 COVID-19 - etiology COVID-19 Drug Treatment Cytokine storm Cytokines Dexamethasone - immunology Dexamethasone - pharmacology Drugs Endothelial cells Epidemics Famotidine - immunology Famotidine - pharmacology Fever Health aspects Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - immunology Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology Immune system Immunomodulating Agents - pharmacology Immunomodulation Immunomodulators Immunosuppressive agents Inflammation Infliximab - immunology Infliximab - pharmacology Interleukin 1 Receptor Antagonist Protein - immunology Interleukin 1 Receptor Antagonist Protein - pharmacology Interleukins Life Sciences Medical Biochemistry Medical research Medicine, Experimental Melatonin - immunology Melatonin - pharmacology Monoclonal antibodies Olfaction disorders Oncology Pandemics Patients Peptidyl-dipeptidase A Pharmacology Physicians Purines - immunology Purines - pharmacology Pyrazoles - immunology Pyrazoles - pharmacology Respiratory diseases Respiratory distress syndrome Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 Signal transduction Signaling Signs and symptoms Sulfonamides - immunology Sulfonamides - pharmacology Viral diseases Viruses Inflammatory responses COVID-19 treatment SARS-CoV-2 Pathophysiology Cytokine storm Immunosuppressive agents
ISSN:	0300-8177, 1573-4919, 1573-4919
Online Access:	Get full text
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