Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations

The B vitamins are components of one-carbon metabolism (OCM) that contribute to DNA synthesis and methylation. Homocysteine, a by-product of OCM, has been associated with coronary heart disease, stroke and neurological disease. To investigate genetic factors that affect circulating vitamin B6, vitam...

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Bibliographic Details
Published in:	American journal of human genetics Vol. 84; no. 4; p. 477
Main Authors:	Tanaka, Toshiko, Scheet, Paul, Giusti, Betti, Bandinelli, Stefania, Piras, Maria Grazia, Usala, Gianluca, Lai, Sandra, Mulas, Antonella, Corsi, Anna Maria, Vestrini, Anna, Sofi, Francesco, Gori, Anna Maria, Abbate, Rosanna, Guralnik, Jack, Singleton, Andrew, Abecasis, Goncalo R, Schlessinger, David, Uda, Manuela, Ferrucci, Luigi
Format:	Journal Article
Language:	English
Published:	United States 01.04.2009
Subjects:	Adult Aged Aged, 80 and over Alkaline Phosphatase - genetics Female Folic Acid - blood Fucosyltransferases - genetics Galactoside 2-alpha-L-fucosyltransferase Genome-Wide Association Study Homocysteine - blood Humans Male Methylenetetrahydrofolate Reductase (NADPH2) - genetics Middle Aged Neoplasm Proteins - genetics Polymorphism, Single Nucleotide Receptors, Cell Surface - genetics Transcobalamins - genetics Vitamin B 12 - blood Vitamin B 6 - blood
ISSN:	1537-6605, 1537-6605
Online Access:	Get more information
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