The effects of tidal volume size and driving pressure levels on pulmonary complement activation: an observational study in critically ill patients

Background Mechanical ventilation can induce or even worsen lung injury, at least in part via overdistension caused by too large volumes or too high pressures. The complement system has been suggested to play a causative role in ventilator-induced lung injury. Aims and methods This was a single-cent...

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Bibliographic Details
Published in:	Intensive care medicine experimental Vol. 8; no. Suppl 1; pp. 74 - 11
Main Authors:	de Beer, Friso M., Wieske, Luuk, van Mierlo, Gerard, Wouters, Diana, Zeerleder, Sacha, Bos, Lieuwe D., Juffermans, Nicole P., Schultz, Marcus J., van der Poll, Tom, Lagrand, Wim K., Horn, Janneke
Format:	Journal Article
Language:	English
Published:	Cham Springer International Publishing 18.12.2020 Springer Nature B.V SpringerOpen
Subjects:	Bronchoalveolar lavage Critical care Critical Care Medicine Driving pressure Injuries Intensive Intensive care Lungs Mechanical ventilation Medicine Medicine & Public Health Observational studies Pneumonia Respiration Tidal volume Ventilators Intensive care Complement activation Driving pressure Bronchoalveolar lavage Complement component 5 Tidal volume Critical care Complement Mechanical ventilation C5a
ISSN:	2197-425X, 2197-425X
Online Access:	Get full text
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