Evolving cognition of the JAK-STAT signaling pathway: autoimmune disorders and cancer

The Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathway is an evolutionarily conserved mechanism of transmembrane signal transduction that enables cells to communicate with the exterior environment. Various cytokines, interferons, growth factors, and other specific...

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Bibliographic Details
Published in:	Signal transduction and targeted therapy Vol. 8; no. 1; pp. 204 - 24
Main Authors:	Xue, Chen, Yao, Qinfan, Gu, Xinyu, Shi, Qingmiao, Yuan, Xin, Chu, Qingfei, Bao, Zhengyi, Lu, Juan, Li, Lanjuan
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 19.05.2023 Nature Publishing Group
Subjects:	631/250/580 692/53 Autoimmune diseases Autoimmune Diseases - drug therapy Autoimmune Diseases - genetics Cancer Research Cell Biology Clinical trials Cognition Cytokines - metabolism Drug development Growth factors Humans Immune response Immunosuppressive agents Internal Medicine Janus kinase Janus Kinase Inhibitors Janus Kinases - metabolism Kinases Malignancy Medicine Medicine & Public Health Neoplasms - drug therapy Neoplasms - genetics Neoplasms - metabolism Oncology Pathology Review Review Article Signal transduction Signal Transduction - genetics STAT Transcription Factors - genetics STAT Transcription Factors - metabolism
ISSN:	2059-3635, 2095-9907, 2059-3635
Online Access:	Get full text
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