COVID-19 pneumonia: ARDS or not?

The lung’s gas volume is high, the recruitability is minimal, and the hypoxemia is likely due to the loss of hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. [...]severe hypoxemia is primarily due to ventilation/perfusion (VA/Q) mismatch. [...]some of these hypoxem...

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Vydáno v:	Critical care (London, England) Ročník 24; číslo 1; s. 154 - 3
Hlavní autoři:	Gattinoni, Luciano, Chiumello, Davide, Rossi, Sandra
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London BioMed Central 16.04.2020 BioMed Central Ltd Springer Nature B.V BMC
Témata:	ARDS Betacoronavirus - isolation & purification Clinical Laboratory Techniques Coronavirus Infections - diagnosis Coronavirus Infections - diagnostic imaging Coronavirus Infections - therapy Coronaviruses COVID-19 COVID-19 Testing Critical care Critical Care Medicine Edema Editorial Emergency Medicine Humans Hypoxemia Intensive Intubation Mechanical ventilation Medicine Medicine & Public Health Pandemics Pneumonia Pneumonia, Viral - diagnostic imaging Pneumonia, Viral - therapy Respiratory distress syndrome Respiratory therapy SARS-CoV-2 Thrombosis Tomography, X-Ray Computed Ventilators United Kingdom COVID-19 Mechanical ventilation ARDS
ISSN:	1364-8535, 1466-609X, 1364-8535, 1466-609X, 1366-609X
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Popis
Shrnutí:	The lung’s gas volume is high, the recruitability is minimal, and the hypoxemia is likely due to the loss of hypoxic pulmonary vasoconstriction and impaired regulation of pulmonary blood flow. [...]severe hypoxemia is primarily due to ventilation/perfusion (VA/Q) mismatch. [...]some of these hypoxemic patients receive CPAP or non-invasive ventilation before ICU admission and present with very high respiratory drives, vigorous inspiratory efforts, and highly negative intrathoracic pressures. [...]in addition to viral pneumonia, those patients likely have self-inflicted ventilator-induced lung injury [4]. Acute Respiratory Distress Syndrome N, Brower RG, Matthay MA, Morris A, Schoenfeld D, Thompson BT, Wheeler A. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
Bibliografie:	SourceType-Scholarly Journals-1 content type line 14 ObjectType-Editorial-2 ObjectType-Commentary-1 content type line 23
ISSN:	1364-8535 1466-609X 1364-8535 1466-609X 1366-609X
DOI:	10.1186/s13054-020-02880-z