Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China
Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Methods Retrospective case series...
Saved in:
| Published in: | Critical care (London, England) Vol. 24; no. 1; pp. 188 - 9 |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
London
BioMed Central
30.04.2020
BioMed Central Ltd Springer Nature B.V BMC |
| Subjects: | |
| ISSN: | 1364-8535, 1466-609X, 1364-8535, 1466-609X, 1366-609X |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Abstract | Background
In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients.
Methods
Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed.
Results
A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness.
Conclusions
A period of 7–13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. |
|---|---|
| AbstractList | Background
In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients.
Methods
Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed.
Results
A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness.
Conclusions
A period of 7–13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed. A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness. A period of 7-13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed. A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness. A period of 7-13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. Abstract Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Methods Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed. Results A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness. Conclusions A period of 7–13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients.BACKGROUNDIn December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients.Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed.METHODSRetrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed.A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness.RESULTSA total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness.A period of 7-13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19.CONCLUSIONSA period of 7-13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Methods Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed. Results A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness. Conclusions A period of 7-13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. Keywords: Coronavirus, Infection, Pneumonia Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was not thoroughly described. We described the clinical courses and prognosis in COVID-19 patients. Methods Retrospective case series of COVID-19 patients from Zhongnan Hospital of Wuhan University in Wuhan and Xishui Hospital, Hubei Province, China, up to February 10, 2020. Epidemiological, demographic, and clinical data were collected. The clinical course of survivors and non-survivors were compared. Risk factors for death were analyzed. Results A total of 107 discharged patients with COVID-19 were enrolled. The clinical course of COVID-19 presented as a tri-phasic pattern. Week 1 after illness onset was characterized by fever, cough, dyspnea, lymphopenia, and radiological multi-lobar pulmonary infiltrates. In severe cases, thrombocytopenia, acute kidney injury, acute myocardial injury, and adult respiratory distress syndrome were observed. During week 2, in mild cases, fever, cough, and systemic symptoms began to resolve and platelet count rose to normal range, but lymphopenia persisted. In severe cases, leukocytosis, neutrophilia, and deteriorating multi-organ dysfunction were dominant. By week 3, mild cases had clinically resolved except for lymphopenia. However, severe cases showed persistent lymphopenia, severe acute respiratory dyspnea syndrome, refractory shock, anuric acute kidney injury, coagulopathy, thrombocytopenia, and death. Older age and male sex were independent risk factors for poor outcome of the illness. Conclusions A period of 7–13 days after illness onset is the critical stage in the COVID-19 course. Age and male gender were independent risk factors for death of COVID-19. |
| ArticleNumber | 188 |
| Audience | Academic |
| Author | Yin, Yimei Prowle, John Wang, Dawei Liu, Xing Jian, Mingzhi Li, Yirong Hu, Chang Peng, Zhiyong Zhou, Shuliang Zhang, Xingguo Hu, Bo Xu, Haibo |
| Author_xml | – sequence: 1 givenname: Dawei surname: Wang fullname: Wang, Dawei organization: Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University – sequence: 2 givenname: Yimei surname: Yin fullname: Yin, Yimei organization: Department of Ultrasound Medicine, Zhongnan Hospital of Wuhan University – sequence: 3 givenname: Chang surname: Hu fullname: Hu, Chang organization: Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University – sequence: 4 givenname: Xing surname: Liu fullname: Liu, Xing organization: Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University – sequence: 5 givenname: Xingguo surname: Zhang fullname: Zhang, Xingguo organization: Department of Critical Care Medicine, Xishui Hospital – sequence: 6 givenname: Shuliang surname: Zhou fullname: Zhou, Shuliang organization: Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University – sequence: 7 givenname: Mingzhi surname: Jian fullname: Jian, Mingzhi organization: Department of Health Education, Center for Disease Control and Prevention – sequence: 8 givenname: Haibo surname: Xu fullname: Xu, Haibo organization: Department of Radiology, Zhongnan Hospital of Wuhan University – sequence: 9 givenname: John surname: Prowle fullname: Prowle, John organization: Adult Critical Care Unit, The Royal London Hospital, Barts Health NHS Trust – sequence: 10 givenname: Bo surname: Hu fullname: Hu, Bo organization: Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University – sequence: 11 givenname: Yirong surname: Li fullname: Li, Yirong email: liyirong838@163.com organization: Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University – sequence: 12 givenname: Zhiyong surname: Peng fullname: Peng, Zhiyong email: Pengzy5@hotmail.com organization: Department of Critical Care Medicine, Zhongnan Hospital of Wuhan University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32354360$$D View this record in MEDLINE/PubMed |
| BookMark | eNp9Ustq3DAUNSWlebQ_0EURdJPFONXLsrUpDEMfgUCh6WMpZFkaK3ikqWRP6C_0q3snkzSZUIIwMtfnnOtz7zkuDkIMtiheE3xGSCPeZcJwxUtMMTyNrErxrDgiTPCyqVh18OD9sDjO-QpjUjeCvSgOGWUVZwIfFX8Wgw_e6AGZOKVskQ4ditNo4sqi6BDBNVrr0dswZuSDs2a0Hbr2Y4_G3qIQN3ZLTTHojU9TnqHL-dfLchF_lHSGOp9Nr9MSKC7FFRqvI-pjXvtRD1s59HPqdZihRe-Dflk8d1C2r27vk-L7xw_fFp_Liy-fzhfzi9IIXI8lFYxr3ZJOOEu1k4LLllHMDeG6I7glba07WUnadrbuHG8r2TS4dg5L1vKas5PifKfbRX2l1smvdPqtovbqphDTUuk0ejNYZXkjoQOtGe64EwYUTCW1lJLW1mENWu93WuupXdnOwJiSHvZE978E36tl3KiaSFqJ7c-c3gqk-GuyeVQrmJkdBh1snLKiTNaiASQG6NtH0CtYWYBRKcoxp5xTzO5RSw0GYGMR-pqtqJqDEU5ZUzWAOvsPCk5nV95AzJyH-h7hzUOj_xzeJQkAzQ5gUsw5WacMbHn0cevbD4pgtQ2t2oVWQWjVTWiVACp9RL1Tf5LEdqQM4LC06X4aT7D-AjuB_NA |
| CitedBy_id | crossref_primary_10_1111_tid_13539 crossref_primary_10_1186_s13054_020_03065_4 crossref_primary_10_3390_diagnostics12020509 crossref_primary_10_3390_vaccines10122043 crossref_primary_10_1080_0092623X_2021_2000535 crossref_primary_10_1111_all_14647 crossref_primary_10_1161_JAHA_121_021046 crossref_primary_10_1186_s43163_021_00186_7 crossref_primary_10_3389_fimmu_2021_801410 crossref_primary_10_3390_diseases8040041 crossref_primary_10_1007_s42399_020_00515_6 crossref_primary_10_1097_PHH_0000000000001257 crossref_primary_10_1016_j_clnesp_2021_03_012 crossref_primary_10_1080_07853890_2020_1790643 crossref_primary_10_1186_s13054_020_03260_3 crossref_primary_10_1007_s12640_021_00389_z crossref_primary_10_1111_all_14657 crossref_primary_10_1186_s13054_020_03077_0 crossref_primary_10_3201_eid2705_204507 crossref_primary_10_14814_phy2_14800 crossref_primary_10_1111_imj_15140 crossref_primary_10_1371_journal_pcbi_1008451 crossref_primary_10_1002_clc_23540 crossref_primary_10_7189_jogh_11_10001 crossref_primary_10_31146_1682_8658_ecg_179_7_143_151 crossref_primary_10_3390_v17030429 crossref_primary_10_1080_13813455_2020_1856141 crossref_primary_10_3390_pathogens9121052 crossref_primary_10_1017_S0950268821000376 crossref_primary_10_1186_s13054_021_03504_w crossref_primary_10_3390_ijerph191912203 crossref_primary_10_1097_MD_0000000000032919 crossref_primary_10_1155_2020_3280908 crossref_primary_10_1080_07853890_2022_2054026 crossref_primary_10_1080_17434440_2021_1915764 crossref_primary_10_1016_j_thromres_2020_08_017 crossref_primary_10_3389_fmed_2021_588013 crossref_primary_10_1016_j_numecd_2020_09_004 crossref_primary_10_1080_21645515_2024_2324549 crossref_primary_10_1016_j_intimp_2020_107159 crossref_primary_10_7554_eLife_63195 crossref_primary_10_3389_fped_2020_607647 crossref_primary_10_3390_jcm9051371 crossref_primary_10_1371_journal_pone_0241541 crossref_primary_10_3390_cancers13246294 crossref_primary_10_1186_s12879_022_07031_z crossref_primary_10_1186_s13054_020_02992_6 crossref_primary_10_7759_cureus_14279 crossref_primary_10_1371_journal_pone_0249655 crossref_primary_10_3390_ijerph17218049 crossref_primary_10_1016_j_mayocp_2020_10_022 crossref_primary_10_1016_j_csbj_2020_12_033 crossref_primary_10_1111_ijlh_13298 crossref_primary_10_1097_SHK_0000000000001738 crossref_primary_10_1007_s00405_021_06900_8 crossref_primary_10_3389_fphar_2020_570721 crossref_primary_10_3390_pathogens11050563 crossref_primary_10_4081_mrm_2020_713 crossref_primary_10_1007_s10072_020_04801_y crossref_primary_10_1016_j_ajem_2020_10_022 crossref_primary_10_1126_scitranslmed_abj7790 crossref_primary_10_1016_j_ajem_2020_10_013 crossref_primary_10_1183_13993003_02108_2020 crossref_primary_10_1111_ans_16260 crossref_primary_10_1108_JICA_08_2023_0066 crossref_primary_10_1186_s12879_020_05252_8 crossref_primary_10_1186_s40001_021_00513_x crossref_primary_10_7861_clinmed_21_2_s36 crossref_primary_10_1080_17476348_2020_1804365 crossref_primary_10_3390_jcm9103218 crossref_primary_10_1016_j_clinimag_2021_06_012 crossref_primary_10_1177_09612033241266875 crossref_primary_10_1186_s12882_021_02244_x crossref_primary_10_1111_dth_13549 crossref_primary_10_1371_journal_pone_0247461 crossref_primary_10_1371_journal_pone_0255154 crossref_primary_10_1002_clc_23465 crossref_primary_10_1016_j_amjcard_2020_06_004 crossref_primary_10_1016_j_sleep_2020_08_010 crossref_primary_10_1093_jleuko_qiaf056 crossref_primary_10_1002_jcla_23412 crossref_primary_10_1016_j_intimp_2020_106950 crossref_primary_10_3389_fphar_2021_607408 crossref_primary_10_1159_000512211 crossref_primary_10_1007_s13318_020_00668_8 crossref_primary_10_4103_jtccm_jtccm_7_21 crossref_primary_10_1007_s00430_020_00696_w crossref_primary_10_1080_20477724_2022_2160892 crossref_primary_10_3390_ijerph19095099 crossref_primary_10_1155_2021_4303380 crossref_primary_10_1177_2040622321998860 crossref_primary_10_1016_j_ajem_2020_05_063 crossref_primary_10_7748_ns_2021_e11667 crossref_primary_10_1002_rmv_2195 crossref_primary_10_1089_mdr_2020_0619 crossref_primary_10_3390_pathogens10010005 crossref_primary_10_3389_fmed_2020_594495 crossref_primary_10_3390_ijerph19106034 crossref_primary_10_1016_j_cmi_2020_12_018 crossref_primary_10_1111_jdi_13431 crossref_primary_10_2459_JCM_0000000000001064 crossref_primary_10_1097_CRD_0000000000000422 crossref_primary_10_1159_000512209 crossref_primary_10_1016_j_jiph_2022_12_019 crossref_primary_10_7748_nop_2021_e1311 crossref_primary_10_1080_03007995_2020_1853510 crossref_primary_10_12688_f1000research_151333_2 crossref_primary_10_12688_f1000research_151333_1 crossref_primary_10_1007_s10787_022_01050_7 crossref_primary_10_1016_j_dsx_2021_102308 crossref_primary_10_1016_j_jinf_2020_06_060 crossref_primary_10_1016_j_ihj_2020_12_002 crossref_primary_10_1016_j_clineuro_2020_106183 crossref_primary_10_9778_cmajo_20200159 crossref_primary_10_3390_geriatrics6010030 crossref_primary_10_1016_j_phrs_2020_105107 crossref_primary_10_1016_j_avsg_2022_04_048 crossref_primary_10_1186_s12916_021_02058_6 crossref_primary_10_1016_j_ijid_2020_12_023 crossref_primary_10_1016_j_jiph_2021_02_001 crossref_primary_10_1111_ijlh_13381 crossref_primary_10_1111_jocn_15688 crossref_primary_10_1016_j_numecd_2020_12_009 crossref_primary_10_63096_medtigo3062323 crossref_primary_10_1016_j_crmeth_2025_101022 crossref_primary_10_1186_s13054_020_03051_w crossref_primary_10_5812_ijem_113220 crossref_primary_10_1002_eji_202350433 crossref_primary_10_12873_411cabral crossref_primary_10_1080_14787210_2021_1902805 crossref_primary_10_34067_KID_0006362020 crossref_primary_10_1371_journal_pone_0241955 crossref_primary_10_1016_j_arcmed_2020_07_005 crossref_primary_10_1177_2151459320972674 crossref_primary_10_24060_2076_3093_202010_3_233_240 crossref_primary_10_3390_microorganisms11030774 crossref_primary_10_1177_20543581211027759 crossref_primary_10_1002_cncr_33160 crossref_primary_10_25122_jml_2021_0341 crossref_primary_10_1007_s11255_020_02740_3 crossref_primary_10_3390_ijerph191911990 crossref_primary_10_1038_s41598_021_90111_y crossref_primary_10_1186_s13048_020_00734_4 crossref_primary_10_3390_jcm9092685 crossref_primary_10_1016_j_pharmthera_2020_107745 crossref_primary_10_1155_2021_6660930 crossref_primary_10_3389_fimmu_2022_899559 crossref_primary_10_1371_journal_pone_0241827 crossref_primary_10_1111_1744_9987_13895 crossref_primary_10_1111_ijn_13112 crossref_primary_10_3389_fphar_2020_607689 crossref_primary_10_1016_j_jinf_2020_05_024 crossref_primary_10_24171_j_phrp_2021_0186 crossref_primary_10_1136_jim_2020_001555 crossref_primary_10_1038_s41598_021_89182_8 crossref_primary_10_7759_cureus_26771 crossref_primary_10_1111_hdi_12861 crossref_primary_10_1016_j_virol_2022_06_006 crossref_primary_10_3389_fmed_2020_585003 crossref_primary_10_1038_s43856_021_00006_2 crossref_primary_10_1002_edm2_338 crossref_primary_10_13105_wjma_v9_i1_74 crossref_primary_10_3889_oamjms_2023_11583 crossref_primary_10_1007_s10072_020_04978_2 crossref_primary_10_1016_j_imu_2023_101188 crossref_primary_10_1186_s13054_020_03134_8 crossref_primary_10_1016_j_dsx_2020_10_014 crossref_primary_10_3233_HAB_220006 crossref_primary_10_1016_j_jcrc_2020_11_006 crossref_primary_10_1093_cid_ciaa1911 crossref_primary_10_1111_aji_13518 crossref_primary_10_1007_s11739_021_02860_3 crossref_primary_10_37689_acta_ape_2022AO0163345 crossref_primary_10_1186_s41927_020_00165_0 crossref_primary_10_7759_cureus_26909 crossref_primary_10_1017_cjn_2021_148 crossref_primary_10_1016_j_micpath_2020_104504 crossref_primary_10_3390_diagnostics12092144 crossref_primary_10_1155_2023_9529563 crossref_primary_10_1371_journal_pone_0238905 crossref_primary_10_1016_j_hjdsi_2020_100512 crossref_primary_10_1371_journal_pone_0254581 crossref_primary_10_1016_j_ijsu_2022_106830 crossref_primary_10_1155_2022_9119930 crossref_primary_10_1097_ALN_0000000000003521 crossref_primary_10_1016_j_ijid_2021_03_008 crossref_primary_10_3390_jcm9072244 crossref_primary_10_1016_j_cmi_2020_10_017 crossref_primary_10_1590_1806_9282_66_s2_112 crossref_primary_10_4103_jpbs_jpbs_460_21 crossref_primary_10_1016_j_nmni_2021_100905 crossref_primary_10_1155_2023_3505657 crossref_primary_10_1186_s13054_020_03171_3 crossref_primary_10_3389_fnut_2024_1458106 crossref_primary_10_1371_journal_pone_0243124 crossref_primary_10_1016_j_chest_2020_10_054 crossref_primary_10_1016_j_phrs_2020_105250 crossref_primary_10_1097_MD_0000000000023353 crossref_primary_10_1016_j_apmr_2020_11_005 crossref_primary_10_37689_acta_ape_2024AR002532 crossref_primary_10_1136_bmjopen_2020_047033 crossref_primary_10_1111_jan_14558 crossref_primary_10_3390_ijerph17165974 crossref_primary_10_1111_ajt_16280 crossref_primary_10_1186_s13054_020_03009_y crossref_primary_10_3389_fimmu_2021_710217 |
| Cites_doi | 10.1016/S0140-6736(20)30154-9 10.1101/2020.01.30.927806 10.1056/NEJMoa2002032 10.1056/NEJMc2001272 10.1101/2020.02.10.20021675 10.1056/NEJMoa2001282 10.1016/S0140-6736(20)30183-5 10.1001/jama.2012.5669 10.1038/s41422-020-0282-0 10.1056/NEJMoa2001316 10.1016/S0140-6736(20)30566-3 10.1056/NEJMc2001468 10.1038/s41586-020-2012-7 10.1001/jama.2020.1585 10.1038/s41564-020-0688-y 10.1016/S0140-6736(20)30211-7 10.1056/NEJMoa2001191 10.1101/2020.01.26.919985 10.1056/NEJMoa2001017 10.1016/S0140-6736(20)30251-8 |
| ContentType | Journal Article |
| Copyright | The Author(s) 2020 COPYRIGHT 2020 BioMed Central Ltd. 2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: The Author(s) 2020 – notice: COPYRIGHT 2020 BioMed Central Ltd. – notice: 2020. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | C6C AAYXX CITATION CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 8FI 8FJ 8FK ABUWG AFKRA AZQEC BENPR CCPQU COVID DWQXO FYUFA GHDGH K9. M0S M1P PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM DOA |
| DOI | 10.1186/s13054-020-02895-6 |
| DatabaseName | Springer Nature OA Free Journals CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Proquest Health and Medical Complete ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials ProQuest Central ProQuest One Community College Coronavirus Research Database ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Publicly Available Content Database ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Central China ProQuest Central ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) ProQuest Central Korea Health & Medical Research Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest One Academic Eastern Edition Coronavirus Research Database ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic Publicly Available Content Database |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1364-8535 1466-609X 1366-609X |
| EndPage | 9 |
| ExternalDocumentID | oai_doaj_org_article_e489f962730d4f6c93bc59a99927ef0a PMC7192564 A627423858 32354360 10_1186_s13054_020_02895_6 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | China United Kingdom |
| GeographicLocations_xml | – name: China – name: United Kingdom |
| GrantInformation_xml | – fundername: National Major Science and Technology Projects of China grantid: 2020ZX09201007 funderid: http://dx.doi.org/10.13039/501100013076 – fundername: National Natural Science Foundation of China grantid: 81701941; 81772046; 81971816 funderid: http://dx.doi.org/10.13039/501100001809 – fundername: National Natural Science Foundation of China grantid: 81701941 – fundername: National Major Science and Technology Projects of China grantid: 2020ZX09201007 – fundername: National Natural Science Foundation of China grantid: 81772046 – fundername: National Natural Science Foundation of China grantid: 81971816 – fundername: ; grantid: 81701941; 81772046; 81971816 – fundername: ; grantid: 2020ZX09201007 |
| GroupedDBID | --- 0R~ 29F 2WC 4.4 53G 5GY 5VS 6J9 6PF 7X7 88E 8FI 8FJ AAFWJ AAJSJ AASML AAWTL ABUWG ACGFS ACJQM ADBBV ADUKV AEGXH AENEX AFKRA AFPKN AHBYD AHMBA AHYZX ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIAM AOIJS BAPOH BAWUL BCNDV BENPR BFQNJ BMC BPHCQ BVXVI C6C CCPQU CS3 DIK E3Z EBD EBLON EBS EMOBN F5P FYUFA GROUPED_DOAJ GX1 HMCUK HYE IAO IHR INH INR ITC KQ8 M1P OK1 PHGZM PHGZT PIMPY PJZUB PPXIY PQQKQ PROAC PSQYO PUEGO RBZ ROL RPM RSV SJN SMD SOJ SV3 TR2 U2A UKHRP WOQ YOC .6V AAYXX AFFHD CITATION -5E -5G -BR 3V. ACRMQ ADINQ ALIPV C24 CGR CUY CVF ECM EIF NPM 7XB 8FK AZQEC COVID DWQXO K9. PKEHL PQEST PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c607t-2634aab1d6fe2af9649b3204c14ad10b1b7ad9592bde7df4b598807ff093b4743 |
| IEDL.DBID | 7X7 |
| ISICitedReferencesCount | 233 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000531320100002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1364-8535 1466-609X |
| IngestDate | Fri Oct 03 12:44:18 EDT 2025 Tue Nov 04 01:59:16 EST 2025 Fri Sep 05 12:39:24 EDT 2025 Tue Oct 14 12:40:55 EDT 2025 Sat Nov 29 13:19:30 EST 2025 Sat Nov 29 10:24:34 EST 2025 Thu Jan 02 22:59:27 EST 2025 Tue Nov 18 22:04:53 EST 2025 Sat Nov 29 06:02:03 EST 2025 Sat Sep 06 07:25:16 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Keywords | Infection Pneumonia Coronavirus |
| Language | English |
| License | Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c607t-2634aab1d6fe2af9649b3204c14ad10b1b7ad9592bde7df4b598807ff093b4743 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23 |
| OpenAccessLink | https://www.proquest.com/docview/2404244203?pq-origsite=%requestingapplication% |
| PMID | 32354360 |
| PQID | 2404244203 |
| PQPubID | 44362 |
| PageCount | 9 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_e489f962730d4f6c93bc59a99927ef0a pubmedcentral_primary_oai_pubmedcentral_nih_gov_7192564 proquest_miscellaneous_2397685640 proquest_journals_2404244203 gale_infotracmisc_A627423858 gale_infotracacademiconefile_A627423858 pubmed_primary_32354360 crossref_citationtrail_10_1186_s13054_020_02895_6 crossref_primary_10_1186_s13054_020_02895_6 springer_journals_10_1186_s13054_020_02895_6 |
| PublicationCentury | 2000 |
| PublicationDate | 2020-04-30 |
| PublicationDateYYYYMMDD | 2020-04-30 |
| PublicationDate_xml | – month: 04 year: 2020 text: 2020-04-30 day: 30 |
| PublicationDecade | 2020 |
| PublicationPlace | London |
| PublicationPlace_xml | – name: London – name: England |
| PublicationTitle | Critical care (London, England) |
| PublicationTitleAbbrev | Crit Care |
| PublicationTitleAlternate | Crit Care |
| PublicationYear | 2020 |
| Publisher | BioMed Central BioMed Central Ltd Springer Nature B.V BMC |
| Publisher_xml | – name: BioMed Central – name: BioMed Central Ltd – name: Springer Nature B.V – name: BMC |
| References | 2895_CR12 2895_CR23 2895_CR11 2895_CR22 2895_CR14 2895_CR13 2895_CR10 2895_CR21 2895_CR20 2895_CR3 2895_CR2 2895_CR1 2895_CR7 2895_CR6 2895_CR19 2895_CR5 VM Ranieri (2895_CR15) 2012; 307 2895_CR4 2895_CR16 2895_CR9 2895_CR18 2895_CR8 2895_CR17 |
| References_xml | – ident: 2895_CR6 doi: 10.1016/S0140-6736(20)30154-9 – ident: 2895_CR19 doi: 10.1101/2020.01.30.927806 – ident: 2895_CR1 doi: 10.1056/NEJMoa2002032 – ident: 2895_CR7 doi: 10.1056/NEJMc2001272 – ident: 2895_CR9 doi: 10.1101/2020.02.10.20021675 – ident: 2895_CR16 – ident: 2895_CR14 – ident: 2895_CR23 doi: 10.1056/NEJMoa2001282 – ident: 2895_CR10 doi: 10.1016/S0140-6736(20)30183-5 – volume: 307 start-page: 2526 issue: 23 year: 2012 ident: 2895_CR15 publication-title: JAMA doi: 10.1001/jama.2012.5669 – ident: 2895_CR22 doi: 10.1038/s41422-020-0282-0 – ident: 2895_CR5 doi: 10.1056/NEJMoa2001316 – ident: 2895_CR21 – ident: 2895_CR13 doi: 10.1016/S0140-6736(20)30566-3 – ident: 2895_CR8 doi: 10.1056/NEJMc2001468 – ident: 2895_CR4 doi: 10.1038/s41586-020-2012-7 – ident: 2895_CR12 doi: 10.1001/jama.2020.1585 – ident: 2895_CR17 doi: 10.1038/s41564-020-0688-y – ident: 2895_CR11 doi: 10.1016/S0140-6736(20)30211-7 – ident: 2895_CR18 doi: 10.1056/NEJMoa2001191 – ident: 2895_CR20 doi: 10.1101/2020.01.26.919985 – ident: 2895_CR2 doi: 10.1056/NEJMoa2001017 – ident: 2895_CR3 doi: 10.1016/S0140-6736(20)30251-8 |
| SSID | ssj0017863 |
| Score | 2.6770325 |
| Snippet | Background
In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of... In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of COVID-19 was... Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and prognosis of... Abstract Background In December 2019, coronavirus disease 2019 (COVID-19) outbreak was reported from Wuhan, China. Information on the clinical course and... |
| SourceID | doaj pubmedcentral proquest gale pubmed crossref springer |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 188 |
| SubjectTerms | Acute Kidney Injury - virology Adult Adult respiratory distress syndrome Age Factors Aged Aged, 80 and over Betacoronavirus Body temperature China Comparative analysis Coronavirus Coronavirus Infections - diagnosis Coronavirus Infections - mortality Coronavirus Infections - therapy Coronaviruses Cough - virology COVID-19 Critical care Critical Care Medicine Data collection Disease transmission Dyspnea Emergency Medicine Epidemiology Female Fever Fever - virology Genomes Heart - virology Hospitals Humans Hypertension Illnesses Infection Intensive Laboratories Lymphopenia - virology Male Medical prognosis Medical records Medicine Medicine & Public Health Middle Aged Neutrophils Pandemics Patient Discharge Patient outcomes Pneumonia Pneumonia, Viral - diagnosis Pneumonia, Viral - mortality Pneumonia, Viral - therapy Prognosis Respiratory Distress Syndrome - virology Retrospective Studies Risk Factors SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Sex Factors Thrombocytopenia - virology Young Adult |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQhRAXxJvQgoyExIGNmsTv41JRcYAKUSi9WbbjaFeqkmpf_Q_8amac7NIUAReuazuyPWP7m52Zbwh5XWvGA7xzuTFNzLnzRe5K4XMlal7UAkB-So8--6hOTvT5ufl8rdQXxoT19MD9xh1Grk2DFWJYUfNGBsN8EMYBrqlUbIoEjQpltsbU4D9QWrJtioyWh0u4qQXP0VRCz5rI5egZSmz9v9_J1x6lmwGTN7ym6TE6vk_uDSiSTvvZPyC3YvuQ3Pk0-MkfkR8D3ecFDR1GaVDX1rRbr0C9Iu0aCtYYHRhVl7SPx4o1xf9kKQBC2nabiEMXANM388V6OaGn0y-n-VF3llcTipm8SLAEQzA7ha6uOjob6o_g5-j39cy1E5pqcz8m347ffz36kA9VF_IgC7XKK8m4c76sZRMrB1vPjWdVwUPJXV0WvvTK1UaYytdR1Q33wsAdoJqmANFwACRPyF7btfEZoaUPlfalDl4K3jimvQTr0WmDIJNJn5FyKwQbBkpyrIxxYZNpoqXtBWdBcDYJzsqMvN2NuewJOf7a-x3KdtcTybTTD6BidlAx-y8Vy8gb1AyLRx6mF9yQuQCLRPIsO5XJ362FzsjBqCcc1TBu3uqWHa6KpQVIhcmGVcEy8mrXjCMx_K2N3Rr6IGrUQvIiI097VdwtiVVMcCahRY2UdLTmcUs7nyUicQXwHj6akclWnX9N6897-vx_7Ok-uVul44h-uQOyt1qs4wtyO2xW8-XiZTrMPwEycEmo priority: 102 providerName: Directory of Open Access Journals – databaseName: SpringerLink Contemporary dbid: RSV link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnR3JjtMw1IIBIS7sS2BARkLiQKNJ4iX2sYwYcYARmsIwN8t2HFpplKCmLf_AV_OemxQyLBJc4_es2Hlr3kbI80ox7kHPpVrXIeXWZanNhUtLUfGsEmDkx_Lo07fl8bE6O9Pv-6Kwbsh2H0KSUVJHtlbyoANpK3iK7g5Gx0QqL5MroO4UDmw4mZ3uYgelkmwoj_kt3kgFxU79v8rjnxTSxWTJCxHTqIiObv7fEW6RG73hSadbSrlNLoXmDrn2rg-t3yXf-g6h59S3mNhBbVPRdr2CnQNtawoOHO2bsHZ0m8IVKoq_cSnYkLRpNwFRl2DZbxbLdTehs-nJLD1sT9NiQrH4F3syAQoWtNDV15bO-5EluB39tJ7bZkLjOO975OPR6w-Hb9J-UEPqZVau0kIybq3LK1mHwtZacu1YkXGfc1vlmctdaSstdOGqUFY1d0KD2CjrOtPMcbBh7pO9pm3CQ0Jz5wvlcuWdFLy2TDkJDqdVGu1SJl1C8uHbGd93McdhGucmejNKmu0lG7hkEy_ZyIS83OF82fbw-Cv0KySJHST2344P2uVn07OzCVzpGucWsazitfRwDi-0BWu7KEOd2YS8QIIyKCXg9bztix3gkNhvy0xlDJEroRKyP4IE7vbj5YEkTS9dOgNWGNYnFhlLyLPdMmJixlwT2jXAoKGphORZQh5sKXh3JFYwwZmElXJE26Mzj1eaxTz2Hi_BI4BNEzIZKPzHa_35Th_9G_hjcr2ITIJBu32yt1quwxNy1W9Wi275NHL7d574TdY priority: 102 providerName: Springer Nature |
| Title | Clinical course and outcome of 107 patients infected with the novel coronavirus, SARS-CoV-2, discharged from two hospitals in Wuhan, China |
| URI | https://link.springer.com/article/10.1186/s13054-020-02895-6 https://www.ncbi.nlm.nih.gov/pubmed/32354360 https://www.proquest.com/docview/2404244203 https://www.proquest.com/docview/2397685640 https://pubmed.ncbi.nlm.nih.gov/PMC7192564 https://doaj.org/article/e489f962730d4f6c93bc59a99927ef0a |
| Volume | 24 |
| WOSCitedRecordID | wos000531320100002&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVADU databaseName: BioMedCentral customDbUrl: eissn: 1364-8535 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017863 issn: 1364-8535 databaseCode: RBZ dateStart: 19970101 isFulltext: true titleUrlDefault: https://www.biomedcentral.com/search/ providerName: BioMedCentral – providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1364-8535 dateEnd: 20231231 omitProxy: false ssIdentifier: ssj0017863 issn: 1364-8535 databaseCode: DOA dateStart: 19980101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1364-8535 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017863 issn: 1364-8535 databaseCode: 7X7 dateStart: 20150101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1364-8535 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017863 issn: 1364-8535 databaseCode: BENPR dateStart: 20150101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1364-8535 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017863 issn: 1364-8535 databaseCode: PIMPY dateStart: 20150101 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVAVX databaseName: SpringerLink Contemporary customDbUrl: eissn: 1364-8535 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0017863 issn: 1364-8535 databaseCode: RSV dateStart: 19970401 isFulltext: true titleUrlDefault: https://link.springer.com/search?facet-content-type=%22Journal%22 providerName: Springer Nature |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpR3bbtMw1IINIV64DwKjMhISD9RaLrbjPKFu2gQSq6oWSnmKbCehlaZk9MY_8NWc47odGWIvvERKbKc59bn63Ah5U6iEW5BzLMuqknFtQqYjYVgqCh4WApR8lx49_pT2-2oyyQb-wG3hwyq3PNEx6qKxeEZ-BJIHc7LiMHl_-YNh1yj0rvoWGrfJPrbNRjxPJzuDK0qV66QWJZIzEEtimzSj5NECeLfgDI0n9LUJJluCydXv_5tL_yGmrodQXvOjOvF09uB_AXtI7nvFlPY2mPSI3Crrx-TuuXe9PyG_fAXRC2obDPygui5os1rCj5S0qSgYeNQXaV3QTYhXWVA85qWgY9K6WZe4dA6a_3o2Xy26dNQbjthJM2Zxl2JyMNZsgiWY8EKXPxs69S1N8HX062qq6y517b6fki9np59PPjDfyIFZGaZLFsuEa22iQlZlrKtM8swkcchtxHURhSYyqS4ykcWmKNOi4kZkwFbSqgqzxHDQcQ7IXt3U5XNCI2NjZSJljRS80okyEgxSrTLUWxNpAhJtdzG3vso5Ntu4yJ21o2S-2fkcdj53O5_LgLzbrbnc1Pi4cfYxIsduJtbndg-a-ffck3tecpVV2NcoCQteSQtwWJFp0MbjtKxCHZC3iFo5chH4PKt9MgQAifW48p50LnQlVEAOWzOB-m17eItVuec-i_wKpQLyejeMKzGiri6bFcxBRVQJycOAPNvg8g6kJE4ETySMpC0sb8HcHqlnU1ebPAWLAV4akO6WHq4-69__6YuboXhJ7sWOUtGJd0j2lvNV-YrcsevlbDHvOJp3V9Uh-8en_cGw445W4G7w8XzwDe6Go_FvLdlfng |
| linkProvider | ProQuest |
| linkToHtml | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1Jb9QwFLZKQcCFfQkUMBKIA2M1i-04B4SGQtWq0wrRUnoztuPQSlVSZmnFX-DH8Bt5z5NMmSJ664FrvCjPedsXv4WQF6XKuAM7x4qi8owbGzOTCMtyUfK4FODkh_To3UG-taX29oqPC-RXlwuDYZWdTgyKumwc_iNfBsuDOVlpnL09-s6waxTernYtNKZsseF_nABkG71Zfw_f92Warn7YWVljbVcB5mScj1kqM26MTUpZ-dRUheSFzdKYu4SbMoltYnNTFqJIbenzsuJWFMDjeVUB9rccDC7se4lcBj2eI9jL92YAL8lV6NyWZJIzMIOiS9JRcnkEtkJwhmAN7_YEk3OGMPQL-Nsq_GEWz4Zsnrm3DeZw9eb_dpC3yI3W8ab9qaTcJgu-vkOubrahBXfJz7ZC6iF1DQa2UFOXtJmMgShPm4oCgKVtEdoRnYaw-ZLib2wKPjStm2OPS4eAbI4PhpNRj273P22zlWaXpT2Kyc9YkwqWYEIPHZ80dL9t2YLb0S-TfVP3aGhnfo98vpCTuE8W66b2DwlNrEuVTZSzUvDKZMpKANxGFeiXZ9JGJOm4Rru2ijs2EznUAc0pqaecpoHTdOA0LSPyerbmaFrD5NzZ75AZZzOx_nh40Ay_6Vadac9VUWHfpiwueSUd0OFEYQBtpLmvYhORV8jKGrUkvJ4zbbIHEIn1xnRfhhABJVREluZmgnZz88MdF-tWu470KQtH5PlsGFdixGDtmwnMQUdbCcnjiDyYys6MpCzNBM8kjORzUjVH8_xIfbAfaq_ngIhg04j0Ovk7fa1_n-mj86l4Rq6t7WwO9GB9a-MxuZ4GLYEXlktkcTyc-CfkijseH4yGT4O-oeTrRcvlb89btoI |
| linkToPdf | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwELdgoIkXvj8CA4yExAONlsSOYz-WQQViVBOFsTfLn7TSlExtWv4H_mp8TlrW8SEhXuu7NOeez3e9u98h9NxyQk2451IhvEup0lmq8lKnVWlpZsvg5Mf26OPDajzmJyfi6FwXf6x2X6cku54GQGmq2_0z67sjztn-IljekqYQ-kCmrEzZZXSFQiE9xOuT400eoeKMrFtlfsu3dR1F1P5fbfO5y-li4eSF7Gm8lEY3_l-cm-h675DiYadBt9AlV99Gux_6lPsd9L1HDj3FpoGCD6xqi5tlG77F4cbjENjhHpx1gbvSLmcx_L2Lg2-J62blgHUePP7VbL5cDPBk-HGSHjTHaTHA0BQMWE2BBRpdcPutwdN-lAk8Dn9ZTlU9wHHM9130efTm08HbtB_gkBqWVW1aMEKV0rll3hXKC0aFJkVGTU6VzTOd60pZUYpCW1dZT3UpgjmpvM8E0TT4NvfQTt3U7gHCuTYF1zk3mpXUK8I1C4Go4gL8VcJ0gvL17yhNj24OQzZOZYxyOJPdJsuwyTJusmQJernhOeuwPf5K_QrUY0MJuNzxg2b-VfbHXDrKhYd5RiSz1DMT5DClUMELLyrnM5WgF6BcEqxHeD2j-iaIICTgcMkhi6lzXvIE7W1RhlNvtpfX6il7q7OQwTuDvsUiIwl6tlkGTqikq12zDDTggPKS0SxB9ztt3ohEClJSwsJKtaXnWzJvr9SzacQkr0KkEB6aoMFa23--1p_39OG_kT9Fu0evR_Lw3fj9I3StiOcF8np7aKedL91jdNWs2tli_iQagR9uQ1me |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Clinical+course+and+outcome+of+107+patients+infected+with+the+novel+coronavirus%2C+SARS-CoV-2%2C+discharged+from+two+hospitals+in+Wuhan%2C+China&rft.jtitle=Critical+care+%28London%2C+England%29&rft.au=Wang%2C+Dawei&rft.au=Yin%2C+Yimei&rft.au=Hu%2C+Chang&rft.au=Liu%2C+Xing&rft.date=2020-04-30&rft.pub=BioMed+Central+Ltd&rft.issn=1364-8535&rft.volume=24&rft.issue=1&rft_id=info:doi/10.1186%2Fs13054-020-02895-6&rft.externalDocID=A627423858 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1364-8535&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1364-8535&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1364-8535&client=summon |