Effects of dietary methionine and cysteine restriction on plasma biomarkers, serum fibroblast growth factor 21, and adipose tissue gene expression in women with overweight or obesity: a double-blind randomized controlled pilot study

Background Dietary restriction of methionine and cysteine is a well-described model that improves metabolic health in rodents. To investigate the translational potential in humans, we evaluated the effects of dietary methionine and cysteine restriction on cardiometabolic risk factors, plasma and uri...

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Bibliographic Details
Published in:	Journal of translational medicine Vol. 18; no. 1; pp. 122 - 15
Main Authors:	Olsen, Thomas, Øvrebø, Bente, Haj-Yasein, Nadia, Lee, Sindre, Svendsen, Karianne, Hjorth, Marit, Bastani, Nasser E., Norheim, Frode, Drevon, Christian A., Refsum, Helga, Vinknes, Kathrine J.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 11.03.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adipose Tissue Amino acids Biological markers Biomarkers Biomedical and Life Sciences Biomedicine Body fat Body weight Cysteine Cystine Diet Dietary intervention Dietary restrictions Double-blind studies Fasting Fibroblast Growth Factors Gene Expression Genes Genetic aspects Genetic markers Genetic research Health Health aspects Humans Insulin Medicine/Public Health Messenger RNA Methionine Methionine restriction mRNA expression Nutrition & metabolism Obesity Obesity - genetics Overweight Overweight - genetics Pilot Projects Plasma biomarkers RNA Rodents Translational research Women Norway Dietary intervention Translational research Adipose tissue Plasma biomarkers Methionine restriction mRNA expression
ISSN:	1479-5876, 1479-5876
Online Access:	Get full text
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