Severe periodontitis enhances macrophage activation via increased serum lipopolysaccharide

In periodontitis, overgrowth of Gram-negative bacteria and access of lipopolysaccharide (LPS) to circulation may activate macrophages leading to foam cell formation. We investigated whether periodontal treatment affects proatherogenic properties of low-density lipoprotein (LDL) and, thus, macrophage...

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Bibliographic Details

Published in:	Arteriosclerosis, thrombosis, and vascular biology Vol. 24; no. 11; p. 2174
Main Authors:	Pussinen, Pirkko J, Vilkuna-Rautiainen, Tiina, Alfthan, Georg, Palosuo, Timo, Jauhiainen, Matti, Sundvall, Jouko, Vesanen, Marja, Mattila, Kimmo, Asikainen, Sirkka
Format:	Journal Article
Language:	English
Published:	United States 01.11.2004
Subjects:	Animals Cell Line Cholesterol, LDL - metabolism Female Humans Lipopolysaccharides - blood Macrophage Activation - physiology Macrophages - metabolism Male Mice Middle Aged Periodontitis - pathology
ISSN:	1524-4636, 1524-4636
Online Access:	Get more information
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