Platelets reduce anoikis and promote metastasis by activating YAP1 signaling

Thrombocytosis is present in more than 30% of patients with solid malignancies and correlates with worsened patient survival. Tumor cell interaction with various cellular components of the tumor microenvironment including platelets is crucial for tumor growth and metastasis. Although it is known tha...

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Veröffentlicht in:Nature communications Jg. 8; H. 1; S. 310 - 15
Hauptverfasser: Haemmerle, Monika, Taylor, Morgan L., Gutschner, Tony, Pradeep, Sunila, Cho, Min Soon, Sheng, Jianting, Lyons, Yasmin M., Nagaraja, Archana S., Dood, Robert L., Wen, Yunfei, Mangala, Lingegowda S., Hansen, Jean M., Rupaimoole, Rajesha, Gharpure, Kshipra M., Rodriguez-Aguayo, Cristian, Yim, Sun Young, Lee, Ju-Seog, Ivan, Cristina, Hu, Wei, Lopez-Berestein, Gabriel, Wong, Stephen T., Karlan, Beth Y., Levine, Douglas A., Liu, Jinsong, Afshar-Kharghan, Vahid, Sood, Anil K.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: London Nature Publishing Group UK 21.08.2017
Nature Publishing Group
Nature Portfolio
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ISSN:2041-1723, 2041-1723
Online-Zugang:Volltext
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