Bone metastases from a 1p/19q codeleted and IDH1-mutant anaplastic oligodendroglioma: a case report

Background Oligodendroglioma is a rare type of primary brain tumor which, like other malignant gliomas, metastasizes very rarely even when in high-grade form. Case report A 36-year-old white man diagnosed 29 months previously as having 1p/19q codeleted anaplastic oligodendroglioma presented bilatera...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Journal of medical case reports Ročník 13; číslo 1; s. 202 - 5
Hlavní autoři: Burgy, Mickaël, Chenard, Marie-Pierre, Noël, Georges, Bourahla, Khalil, Schott, Roland
Médium: Journal Article
Jazyk:angličtina
Vydáno: London BioMed Central 28.06.2019
BioMed Central Ltd
BMC
Témata:
Adult
Anaplastic oligodendroglioma
Base Sequence
Bone marrow biopsy
Bone metastases
Bone Neoplasms - genetics
Bone Neoplasms - secondary
Brain Neoplasms - genetics
Brain Neoplasms - pathology
Brain tumors
Cancer metastasis
Care and treatment
Case Report
CAT scans
Chromosomes, Human, Pair 1
Diagnosis
Diagnostic imaging
Family Medicine
Gene mutation
General Practice
Genetic aspects
Gliomas
Humans
Internal Medicine
Isocitrate Dehydrogenase - genetics
Male
Medicine
Medicine & Public Health
Metastatic oligodendroglioma
Oligodendroglioma
Oligodendroglioma - genetics
Oligodendroglioma - secondary
Primary Care Medicine
Public Health
Sequence Deletion
Surgical Oncology
Tomography
Tumors
Vincristine
Metastatic oligodendroglioma
Bone metastases
Anaplastic oligodendroglioma
ISSN:1752-1947, 1752-1947
On-line přístup:Získat plný text
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!
Popis
Shrnutí:Background Oligodendroglioma is a rare type of primary brain tumor which, like other malignant gliomas, metastasizes very rarely even when in high-grade form. Case report A 36-year-old white man diagnosed 29 months previously as having 1p/19q codeleted anaplastic oligodendroglioma presented bilateral cruralgia and lower limb motor deficits. A computed tomography scan showed multiple osteoblastic bone lesions. The presence of oligodendroglial cells was revealed by bone marrow biopsy and confirmed by immunohistochemical analyses. A positon emission tomography-computed tomography scan confirmed the exclusive involvement of bones. Conclusion This case joins less than 20 other reported cases of oligodendroglioma bone marrow metastasis, and is one of only a handful of cases of diffuse bone metastases beyond the axial skeleton. To the best of our knowledge, the early relapse of 1p/19q codeleted anaplastic oligodendroglioma with this distribution of metastases has never been described in the literature.
Bibliografie:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:1752-1947
1752-1947
DOI:10.1186/s13256-019-2061-4