Regulated cell death pathways in doxorubicin-induced cardiotoxicity

Doxorubicin is a chemotherapeutic drug used for the treatment of various malignancies; however, patients can experience cardiotoxic effects and this has limited the use of this potent drug. The mechanisms by which doxorubicin kills cardiomyocytes has been elusive and despite extensive research the e...

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Bibliographic Details
Published in:	Cell death & disease Vol. 12; no. 4; pp. 339 - 15
Main Authors:	Christidi, Effimia, Brunham, Liam R.
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.04.2021 Springer Nature B.V Nature Publishing Group
Subjects:	631/80/304 692/699/75/74 Animals Antibodies Apoptosis Apoptosis - drug effects Autophagy Autophagy - drug effects Biochemistry Biomedical and Life Sciences Cardiomyocytes Cardiotoxicity Cardiotoxicity - metabolism Cell Biology Cell Culture Cell death Chemotherapy Doxorubicin Doxorubicin - pharmacology Ferroptosis Humans Immunology Life Sciences Myocytes, Cardiac - drug effects Myocytes, Cardiac - metabolism Necroptosis Necroptosis - drug effects Phagocytosis Pyroptosis Review Review Article
ISSN:	2041-4889, 2041-4889
Online Access:	Get full text
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