The genomic landscape of Mongolian hepatocellular carcinoma

Mongolia has the highest incidence of hepatocellular carcinoma (HCC) in the world, but its causative factors and underlying tumor biology remain unknown. Here, we describe molecular characteristics of HCC from 76 Mongolian patients by whole-exome and transcriptome sequencing. We present a comprehens...

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Vydáno v:	Nature communications Ročník 11; číslo 1; s. 4383 - 13
Hlavní autoři:	Candia, Julián, Bayarsaikhan, Enkhjargal, Tandon, Mayank, Budhu, Anuradha, Forgues, Marshonna, Tovuu, Lkhagva-Ochir, Tudev, Undarmaa, Lack, Justin, Chao, Ann, Chinburen, Jigjidsuren, Wang, Xin Wei
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 01.09.2020 Nature Publishing Group Nature Portfolio
Témata:	45/23 45/91 631/208/191/2018 631/67/1504/1610/4029 631/67/69 Aged Biomarkers, Tumor - genetics Cancer Carcinogenesis - genetics Carcinoma, Hepatocellular - epidemiology Carcinoma, Hepatocellular - genetics Carcinoma, Hepatocellular - surgery Carcinoma, Hepatocellular - virology DNA Mutational Analysis Etiology Exome Sequencing Female Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Hepatectomy Hepatitis Hepatitis D - epidemiology Hepatitis D - genetics Hepatitis D - surgery Hepatitis D - virology Hepatitis Delta Virus - isolation & purification Hepatocellular carcinoma Humanities and Social Sciences Humans Incidence Liver - pathology Liver - surgery Liver - virology Liver cancer Liver Neoplasms - epidemiology Liver Neoplasms - genetics Liver Neoplasms - surgery Liver Neoplasms - virology Male Middle Aged Molecular modelling Mongolia - epidemiology multidisciplinary Mutation p53 Protein Prognosis Science Science (multidisciplinary) Mongolia
ISSN:	2041-1723, 2041-1723
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