Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke

The concept of the neurovascular unit emphasizes the importance of cell-cell signaling between neural, glial, and vascular compartments. In neurogenesis, for example, brain endothelial cells play a key role by supplying trophic support to neural progenitors. Here, we describe a surprising phenomenon...

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Vydáno v:	Nature communications Ročník 13; číslo 1; s. 7812 - 14
Hlavní autoři:	Li, Wenlu, Mandeville, Emiri T., Durán-Laforet, Violeta, Fukuda, Norito, Yu, Zhanyang, Zheng, Yi, Held, Aaron, Park, Ji-Hyun, Nakano, Takafumi, Tanaka, Masayoshi, Shi, Jingfei, Esposito, Elga, Niu, Wanting, Xing, Changhong, Hayakawa, Kazuhide, Lizasoain, Ignacio, van Leyen, Klaus, Ji, Xunming, Wainger, Brian J., Moro, Maria A., Lo, Eng H.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	London Nature Publishing Group UK 19.12.2022 Nature Publishing Group Nature Portfolio
Témata:	14/28 631/378/2596/1308 631/378/2607 692/699/375/534 Animal models Animals ASCL1 protein Astrocytes Brain Brain damage Cell differentiation Cell signaling Cell Transdifferentiation Cells, Cultured Conversion Deprivation Endothelial Cells Endothelium Glucose Humanities and Social Sciences Ischemia Male Mice multidisciplinary Neural Stem Cells Neurogenesis Neuronal-glial interactions Neuroplasticity Oxygen Progenitor cells Science Science (multidisciplinary) Stroke
ISSN:	2041-1723, 2041-1723
On-line přístup:	Získat plný text
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