Platelets in Patients with Premature Coronary Artery Disease Exhibit Upregulation of miRNA340 and miRNA624

Coronary artery disease (CAD) is the leading cause of human morbidity and mortality worldwide, underscoring the need to improve diagnostic strategies. Platelets play a major role, not only in the process of acute thrombosis during plaque rupture, but also in the formation of atherosclerosis itself....

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Bibliographic Details
Published in:	PloS one Vol. 6; no. 10; p. e25946
Main Authors:	Sondermeijer, Brigitte M., Bakker, Annemieke, Halliani, Amalia, de Ronde, Maurice W. J., Marquart, Arnoud A., Tijsen, Anke J., Mulders, Ties A., Kok, Maayke G. M., Battjes, Suzanne, Maiwald, Steffi, Sivapalaratnam, Suthesh, Trip, Mieke D., Moerland, Perry D., Meijers, Joost C. M., Creemers, Esther E., Pinto-Sietsma, Sara-Joan
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 13.10.2011 Public Library of Science (PLoS)
Subjects:	Adult Arteriosclerosis Atherosclerosis Bioinformatics Biology Biomarkers Blood platelets Blood Platelets - metabolism Cardiac patients Cardiology Cardiovascular disease Care and treatment Case-Control Studies Cohort Studies Coronary artery Coronary artery disease Coronary Artery Disease - genetics Coronary heart disease Coronary vessels Data collection Diagnostic systems Disease control Disease prevention DNA microarrays Epidemiology Family medical history Gene expression Gene Expression Profiling Genetic Association Studies Health aspects Heart attacks Heart diseases Heart failure Humans Male Medical research Medicine MicroRNA MicroRNAs MicroRNAs - genetics MicroRNAs - metabolism Middle Aged miRNA Morbidity Mortality Patients Platelets Reproducibility of Results Ribonucleic acid Risk assessment RNA Teaching hospitals Thromboembolism Thrombosis Up-Regulation - genetics Netherlands
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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