Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies

Since they were first derived more than three decades ago, embryonic stem cells have been proposed as a source of replacement cells in regenerative medicine, but their plasticity and unlimited capacity for self-renewal raises concerns about their safety, including tumour formation ability, potential...

Full description

Saved in:

Bibliographic Details
Published in:	The Lancet (British edition) Vol. 385; no. 9967; pp. 509 - 516
Main Authors:	Schwartz, Steven D, Regillo, Carl D, Lam, Byron L, Eliott, Dean, Rosenfeld, Philip J, Gregori, Ninel Z, Hubschman, Jean-Pierre, Davis, Janet L, Heilwell, Gad, Spirn, Marc, Maguire, Joseph, Gay, Roger, Bateman, Jane, Ostrick, Rosaleen M, Morris, Debra, Vincent, Matthew, Anglade, Eddy, Del Priore, Lucian V, Lanza, Robert
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 07.02.2015 Elsevier Limited
Subjects:	Adult Aged Aged, 80 and over Cell Differentiation Dystrophy Embryonic Stem Cells - cytology Embryonic Stem Cells - transplantation Eye Female Follow-Up Studies Humans Internal Medicine Macular degeneration Macular Degeneration - therapy Male Middle Aged Pigmentation Pigments Prospective Studies Quality of Life Retina Retinal Pigment Epithelium - cytology Retinal Pigment Epithelium - transplantation Safety Stem cells Transplants & implants Treatment Outcome Visual Acuity Young Adult
ISSN:	0140-6736, 1474-547X, 1474-547X
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!