Characterization of the phenotypic consequences of the Duffy-null genotype

•rs2814778-CC is only reproducibly associated with changes in white blood cell count and not with any disease outcomes.•Race is not an accurate predictor of Duffy-null–associated benign neutropenia; genetic screening of rs2814778 is needed. [Display omitted] A wealth of research focused on African A...

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Vydané v:	Blood advances Ročník 9; číslo 6; s. 1452 - 1462
Hlavní autori:	Hysong, Micah R., Shuey, Megan M., Huffman, Jennifer E., Auer, Paul, Reiner, Alexander, Raffield, Laura M.
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States Elsevier Inc 25.03.2025 The American Society of Hematology Elsevier
Predmet:	Duffy Blood-Group System - genetics Genotype Humans Leukocyte Count Neutropenia - genetics Phagocytes, Granulocytes, and Myelopoiesis Phenotype Polymorphism, Single Nucleotide Receptors, Cell Surface - genetics
ISSN:	2473-9529, 2473-9537, 2473-9537
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