HAlign-II: efficient ultra-large multiple sequence alignment and phylogenetic tree reconstruction with distributed and parallel computing

Background Multiple sequence alignment (MSA) plays a key role in biological sequence analyses, especially in phylogenetic tree construction. Extreme increase in next-generation sequencing results in shortage of efficient ultra-large biological sequence alignment approaches for coping with different...

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Bibliographic Details
Published in:	Algorithms for molecular biology Vol. 12; no. 1; pp. 25 - 10
Main Authors:	Wan, Shixiang, Zou, Quan
Format:	Journal Article
Language:	English
Published:	London BioMed Central 29.09.2017 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Algorithms Alignment Analysis Bioinformatics Biological analysis Biological effects Biomedical and Life Sciences Cellular and Medical Topics Computational Biology/Bioinformatics Computer memory Computer networks Computing costs Computing time Datasets Deoxyribonucleic acid Design Distributed computing Distributed processing DNA DNA sequencing Efficiency Fault tolerance Fourier transforms Genomes International conferences Internet Internet server software Life Sciences Methods Multiple sequence alignment Nucleotide sequence Phylogenetic trees Phylogenetics Phylogeny Physiological Proteins Servers Software Software development tools Source code Spark Technology application China Phylogenetic trees Spark Multiple sequence alignment Distributed computing
ISSN:	1748-7188, 1748-7188
Online Access:	Get full text
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