Mortality after hospital admission for heart failure: improvement over time, equally strong in women as in men
Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000–31.12.2002 and between 01.01.2008–31.12.2010, were constructed...
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| Published in: | BMC public health Vol. 20; no. 1; pp. 36 - 10 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
| Language: | English |
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BioMed Central
10.01.2020
BioMed Central Ltd Springer Nature B.V BMC |
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| ISSN: | 1471-2458, 1471-2458 |
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| Abstract | Background
To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands.
Methods
Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000–31.12.2002 and between 01.01.2008–31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time.
Results
We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74–75 and 78–79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008–10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25–54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women.
Conclusions
Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. |
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| AbstractList | To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands.
Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000-31.12.2002 and between 01.01.2008-31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time.
We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74-75 and 78-79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008-10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25-54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women.
Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. Abstract Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000–31.12.2002 and between 01.01.2008–31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time. Results We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74–75 and 78–79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008–10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25–54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women. Conclusions Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000-31.12.2002 and between 01.01.2008-31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time. We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74-75 and 78-79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008-10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25-54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women. Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000–31.12.2002 and between 01.01.2008–31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time. Results We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74–75 and 78–79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008–10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25–54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women. Conclusions Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands.BACKGROUNDTo assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands.Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000-31.12.2002 and between 01.01.2008-31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time.METHODSTwo nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000-31.12.2002 and between 01.01.2008-31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time.We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74-75 and 78-79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008-10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25-54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women.RESULTSWe identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74-75 and 78-79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008-10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25-54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women.Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men.CONCLUSIONSMortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000–31.12.2002 and between 01.01.2008–31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time. Results We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74–75 and 78–79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008–10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25–54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women. Conclusions Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two nationwide cohorts of patients, hospitalized for new onset heart failure between 01.01.2000-31.12.2002 and between 01.01.2008-31.12.2010, were constructed by linkage of the Dutch Hospital Discharge Registry and the National Cause of Death registry. 30-day, 1-year and 5 -year overall and cause-specific mortality rates stratified by age and sex were assessed and compared over time. Results We identified 40,230 men and 41,582 women. In both cohorts, men were on average younger than women (74-75 and 78-79 years, respectively) and more often had comorbid conditions (37 and 30%, respectively). In the 2008-10 cohort, mortality rates for men were 13, 32 and 64% for respectively 30-day, 1-year and 5-year mortality and 14, 33 and 66% for women. Mortality rates increased considerably with age similarly in men and women (e.g. from 10.5% in women aged 25-54 to 46.1% in those aged 85 and older after 1 year). Between the two time periods, mortality rates dropped across all ages, equally strong in women as in men. The 1-year absolute risk of death declined by 4.0% (from 36.1 to 32.1%) in men and 3.2% (from 36.2 to 33.0%) in women. Conclusions Mortality after hospitalization for new onset HF remains high, however, both short-term and long-term survival is improving over time. This improvement was similar across all ages and equally strong in women as in men. Keywords: Prognosis, Heart failure, Mortality, Trends, Sex, Age |
| ArticleNumber | 36 |
| Audience | Academic |
| Author | Visseren, F. L. J. den Ruijter, H. M. Rutten, F. H. Buddeke, J. van Dis, I. Valstar, G. B. Bots, M. L. Vaartjes, I. |
| Author_xml | – sequence: 1 givenname: J. surname: Buddeke fullname: Buddeke, J. organization: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Dutch Heart Foundation – sequence: 2 givenname: G. B. surname: Valstar fullname: Valstar, G. B. organization: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University – sequence: 3 givenname: I. surname: van Dis fullname: van Dis, I. organization: Dutch Heart Foundation – sequence: 4 givenname: F. L. J. surname: Visseren fullname: Visseren, F. L. J. organization: Department of Vascular Medicine, University Medical Center Utrecht, Utrecht University – sequence: 5 givenname: F. H. surname: Rutten fullname: Rutten, F. H. organization: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University – sequence: 6 givenname: H. M. surname: den Ruijter fullname: den Ruijter, H. M. organization: Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University – sequence: 7 givenname: I. surname: Vaartjes fullname: Vaartjes, I. organization: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Dutch Heart Foundation – sequence: 8 givenname: M. L. surname: Bots fullname: Bots, M. L. email: m.l.bots@umcutrecht.nl organization: Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31924185$$D View this record in MEDLINE/PubMed |
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| Keywords | Heart failure Prognosis Trends Mortality Age Sex |
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| References | SS Rathore (7934_CR4) 2005; 149 V De Groot (7934_CR14) 2003; 56 GC Fonarow (7934_CR15) 2009; 104 SW Joffe (7934_CR8) 2013; 2 Meta-analysis Global Group in Chronic Heart Failure (MAGGIC) (7934_CR9) 2012; 33 7934_CR12 Carla Koopman (7934_CR17) 2016; 11 PS Jhund (7934_CR19) 2009; 119 I Vaartjes (7934_CR6) 2010; 10 Y Gerber (7934_CR1) 2015; 175 DJ Nieuwkamp (7934_CR24) 2014; 9 V Sundararajan (7934_CR13) 2004; 57 A van Oeffelen (7934_CR10) 2014; 100 FJV Schlösser (7934_CR25) 2010; 251 K MacIntyre (7934_CR3) 2000; 102 HL Koek (7934_CR11) 2007; 65 AH Merry (7934_CR21) 2009; 24 AAM Van Oeffelen (7934_CR18) 2015; 10 VL Roger (7934_CR7) 2004; 292 F Najafi (7934_CR5) 2007; 9 SM Dunlay (7934_CR2) 2017; 14 TE Owan (7934_CR20) 2006; 355 DS Lee (7934_CR22) 2005; 43 EI De Bruin (7934_CR23) 2003 Carla Koopman (7934_CR16) 2013; 34 |
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To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands.
Methods
Two nationwide... To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Two nationwide cohorts of patients,... Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two nationwide... To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Two nationwide cohorts of patients,... To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands.BACKGROUNDTo assess the trend in age-... Abstract Background To assess the trend in age- and sex-stratified mortality after hospitalization for heart failure (HF) in the Netherlands. Methods Two... |
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| SubjectTerms | Adult Age Age Distribution Age groups Aged Aged, 80 and over Biostatistics Cancer Cardiovascular disease Chronic Disease epidemiology Chronic obstructive pulmonary disease Codes Cohort Studies Comorbidity Congestive heart failure Death Demographic aspects Environmental Health Epidemiology Female Gender differences Heart attacks Heart failure Heart Failure - mortality Heart Failure - therapy Hospital patients Hospitalization Hospitalization - statistics & numerical data Hospitals Humans Male Medical prognosis Medicine Medicine & Public Health Men Middle Aged Mortality Mortality - trends Netherlands Netherlands - epidemiology Patient outcomes Prognosis Public Health Research Article Sex Sex Distribution Sexes Short term Survival Time Trends Vaccine Women Womens health |
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| Title | Mortality after hospital admission for heart failure: improvement over time, equally strong in women as in men |
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