Needle-free delivery of measles virus vaccine to the lower respiratory tract of non-human primates elicits optimal immunity and protection

Needle-free measles virus vaccination by aerosol inhalation has many potential benefits. The current standard route of vaccination is subcutaneous injection, whereas measles virus is an airborne pathogen. However, the target cells that support replication of live-attenuated measles virus vaccines in...

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Bibliographic Details
Published in:	npj vaccines Vol. 2; no. 1; pp. 22 - 11
Main Authors:	de Swart, Rik L., de Vries, Rory D., Rennick, Linda J., van Amerongen, Geert, McQuaid, Stephen, Verburgh, R. Joyce, Yüksel, Selma, de Jong, Alwin, Lemon, Ken, Nguyen, D. Tien, Ludlow, Martin, Osterhaus, Albert D. M. E., Duprex, W. Paul
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 01.08.2017 Nature Publishing Group Nature Portfolio
Subjects:	631/250/590/1867 692/699/255/2514 Aerosols Biomedical and Life Sciences Biomedicine Drug administration Hypodermic needles Immunity (Disease) Immunization Immunogenicity Infectious Diseases Inhalation Injection Lymph nodes Lymphocytes Measles Medical Microbiology Pathogens Public Health Respiratory tract Vaccine Vaccines Virology
ISSN:	2059-0105, 2059-0105
Online Access:	Get full text
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