Intestinal epithelial cell transported TLR2 ligand stimulates Ly6C+ monocyte differentiation in a G-CSF dependent manner

Microflora-induced TLR signaling in the intestinal epithelium is essential for a proper intestinal barrier function. Because of the close interactions of this epithelial layer with underlying mononuclear phagocytes, we hypothesized that epithelial TLR signaling may affect the differentiation of myel...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	Immunobiology (1979) Ročník 220; číslo 11; s. 1255 - 1265
Hlavní autoři:	Hiemstra, Ida H., Vrijland, Kim, Hogenboom, Marye M., Bouma, Gerd, Kraal, Georg, den Haan, Joke M.M.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier GmbH 01.11.2015
Témata:	Advanced Basic Science Allergy and Immunology Animals Antigens, Ly - metabolism Cell Differentiation - drug effects Cells, Cultured Dendritic cell Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Granulocyte Colony-Stimulating Factor - biosynthesis Granulocyte Colony-Stimulating Factor - pharmacology Intestinal epithelial cells Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Intestinal Mucosa - microbiology Leukocyte Count Ligands Lipopeptides - pharmacology Mice Microflora Monocyte differentiation Monocytes - drug effects Monocytes - physiology Toll-Like Receptor 2 - agonists Toll-Like Receptor 2 - metabolism Transcytosis Dendritic cell M-CSF GM-CSF Intestinal epithelial cells Microflora Flt3L BM TLR G-CSF Monocyte differentiation DC granulocyte macrophage colony-stimulating factor FMS-like tyrosine kinase 3 ligand granulocyte colony-stimulating factor bone marrow toll-like receptor dendritic cell macrophage colony-stimulating factor
ISSN:	0171-2985, 1878-3279
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!