Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation

Global gene expression profiling has been widely used in lung cancer research to identify clinically relevant molecular subtypes as well as to predict prognosis and therapy response. So far, the value of these multigene signatures in clinical practice is unclear, and the biologic importance of indiv...

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Bibliographic Details
Published in:	Clinical cancer research Vol. 19; no. 1; p. 194
Main Authors:	Botling, Johan, Edlund, Karolina, Lohr, Miriam, Hellwig, Birte, Holmberg, Lars, Lambe, Mats, Berglund, Anders, Ekman, Simon, Bergqvist, Michael, Pontén, Fredrik, König, André, Fernandes, Oswaldo, Karlsson, Mats, Helenius, Gisela, Karlsson, Christina, Rahnenführer, Jörg, Hengstler, Jan G, Micke, Patrick
Format:	Journal Article
Language:	English
Published:	United States 01.01.2013
Subjects:	Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Cell Adhesion Molecule-1 Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Cluster Analysis Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Immunoglobulins - genetics Immunoglobulins - metabolism Lung Neoplasms - genetics Lung Neoplasms - mortality Lung Neoplasms - pathology Male Middle Aged Neoplasm Staging Prognosis Reproducibility of Results
ISSN:	1078-0432, 1557-3265, 1557-3265
Online Access:	Get more information
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