Biomarker discovery in non-small cell lung cancer: integrating gene expression profiling, meta-analysis, and tissue microarray validation

Global gene expression profiling has been widely used in lung cancer research to identify clinically relevant molecular subtypes as well as to predict prognosis and therapy response. So far, the value of these multigene signatures in clinical practice is unclear, and the biologic importance of indiv...

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Vydáno v:	Clinical cancer research Ročník 19; číslo 1; s. 194
Hlavní autoři:	Botling, Johan, Edlund, Karolina, Lohr, Miriam, Hellwig, Birte, Holmberg, Lars, Lambe, Mats, Berglund, Anders, Ekman, Simon, Bergqvist, Michael, Pontén, Fredrik, König, André, Fernandes, Oswaldo, Karlsson, Mats, Helenius, Gisela, Karlsson, Christina, Rahnenführer, Jörg, Hengstler, Jan G, Micke, Patrick
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.01.2013
Témata:	Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Cell Adhesion Molecule-1 Cell Adhesion Molecules - genetics Cell Adhesion Molecules - metabolism Cluster Analysis Female Gene Expression Profiling Gene Expression Regulation, Neoplastic Humans Immunoglobulins - genetics Immunoglobulins - metabolism Lung Neoplasms - genetics Lung Neoplasms - mortality Lung Neoplasms - pathology Male Middle Aged Neoplasm Staging Prognosis Reproducibility of Results
ISSN:	1078-0432, 1557-3265, 1557-3265
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