Early-life stress impairs postnatal oligodendrogenesis and adult emotional behaviour through activity-dependent mechanisms

Exposure to stress during early life (infancy/childhood) has long-term effects on the structure and function of the prefrontal cortex (PFC), and increases the risk for adult depression and anxiety disorders. However, little is known about the molecular and cellular mechanisms of these effects. Here,...

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Bibliographic Details
Published in:	Molecular psychiatry Vol. 25; no. 6; pp. 1159 - 1174
Main Authors:	Teissier, Anne, Le Magueresse, Corentin, Olusakin, Jimmy, Andrade da Costa, Belmira L S, De Stasi, Angela M, Bacci, Alberto, Imamura Kawasawa, Yuka, Vaidya, Vidita A, Gaspar, Patricia
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.06.2020
Subjects:	Animal behavior Animals Anxiety disorders Behavior, Animal Cell Proliferation Children Emotional behavior Emotions Excitability Female Gene expression Genomes Immediate-early proteins Juveniles Long-term effects Male Maternal Deprivation Mice Myelin Oligodendrocytes Oligodendroglia - pathology Pattern recognition Physiology Prefrontal cortex Prefrontal Cortex - pathology Prefrontal Cortex - physiopathology Pregnancy Short term memory Stress Stress, Psychological Structure-function relationships Temporal lobe Weaning
ISSN:	1359-4184, 1476-5578, 1476-5578
Online Access:	Get full text
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